GR34667B - Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων. - Google Patents

Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων.

Info

Publication number
GR34667B
GR34667B GR670134667A GR670134667A GR34667B GR 34667 B GR34667 B GR 34667B GR 670134667 A GR670134667 A GR 670134667A GR 670134667 A GR670134667 A GR 670134667A GR 34667 B GR34667 B GR 34667B
Authority
GR
Greece
Prior art keywords
cat
alkylamino
alkoxy
preparation
substituted
Prior art date
Application number
GR670134667A
Other languages
Greek (el)
English (en)
Original Assignee
Merck & Co, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co, Inc filed Critical Merck & Co, Inc
Publication of GR34667B publication Critical patent/GR34667B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48Y being a hydrogen or a carbon atom
    • C07C275/50Y being a hydrogen or an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/10Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR670134667A 1966-10-03 1967-09-22 Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων. GR34667B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58393766A 1966-10-03 1966-10-03

Publications (1)

Publication Number Publication Date
GR34667B true GR34667B (el) 1968-06-05

Family

ID=24335223

Family Applications (1)

Application Number Title Priority Date Filing Date
GR670134667A GR34667B (el) 1966-10-03 1967-09-22 Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων.

Country Status (19)

Country Link
US (1) US3517050A (member.php)
AT (2) AT279590B (member.php)
BE (1) BE704574A (member.php)
BR (1) BR6793319D0 (member.php)
CH (1) CH512422A (member.php)
CS (1) CS170496B2 (member.php)
CY (1) CY650A (member.php)
DE (1) DE1643460A1 (member.php)
DK (1) DK120955B (member.php)
ES (1) ES345582A1 (member.php)
FI (1) FI48064C (member.php)
FR (2) FR1573841A (member.php)
GB (1) GB1182007A (member.php)
GR (1) GR34667B (member.php)
MY (1) MY7300079A (member.php)
NL (1) NL149484B (member.php)
NO (1) NO121787B (member.php)
SE (1) SE332182B (member.php)
YU (1) YU32921B (member.php)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923855A (en) * 1972-07-13 1975-12-02 Merck & Co Inc 2-sulfonyloxyethyl 3-trifluoromethylphenoxy-4{40 -chlorophenyl acetate
US4110351A (en) * 1973-04-02 1978-08-29 Richardson-Merrell Inc. Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts
DK115374A (member.php) 1974-03-04 1975-11-03 Byk Gulden Lomberg Chem Fab
IL48707A0 (en) * 1974-12-30 1976-02-29 Synthelabo Novel phenylacetic acid derivatives,their preparation and pharmaceutical compositions containing them
FR2424247A2 (fr) * 1978-04-27 1979-11-23 Science Union & Cie Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
US6624194B1 (en) * 1999-06-04 2003-09-23 Metabolex, Inc. Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US7576131B2 (en) * 1999-06-04 2009-08-18 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
JP2004521124A (ja) * 2001-02-09 2004-07-15 メルク エンド カムパニー インコーポレーテッド 糖尿病および脂質障害用の2−アリールオキシ−2−アリールアルカン酸類
MXPA05013981A (es) * 2003-06-20 2006-03-02 Metabolex Inc Resolucion de derivados de acido a- (fenoxi) fenilacetico.
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
CN100525757C (zh) * 2003-06-20 2009-08-12 麦它波莱克斯股份有限公司 α-(苯氧基)苯乙酸衍生物的拆分
USD492579S1 (en) 2003-10-15 2004-07-06 The Gates Corporation Pulley
CA2555814A1 (en) 2004-02-18 2005-09-01 Metabolex, Inc. Alpha-(trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents
WO2005115384A2 (en) * 2004-05-25 2005-12-08 Metabolex, Inc. Bicyclic, substituted triazoles as modulators of ppar and methods of their preparation
CN1997633A (zh) * 2004-05-25 2007-07-11 麦它波莱克斯股份有限公司 作为ppar调节剂的取代的三唑及其制备方法
US8288438B2 (en) 2005-03-21 2012-10-16 Metabolex, Inc. Methods for avoiding edema in the treatment or prevention of PPARγ-responsive diseases, including cancer
US7432394B2 (en) * 2005-09-23 2008-10-07 Metabolex, Inc. Resolution of α-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
WO2009121940A1 (en) * 2008-04-03 2009-10-08 Janssen Pharmaceutica Nv Process for the preparation of (-)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester
US9023856B2 (en) 2011-11-04 2015-05-05 Cymabay Therapeutics, Inc. Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent
US9060987B2 (en) 2011-11-04 2015-06-23 Cymabay Therapeutics, Inc. Methods for treating gout flares
EP2847152A4 (en) * 2012-05-10 2016-03-23 Cellix Bio Private Ltd COMPOSITIONS AND METHOD FOR THE TREATMENT OF METABOLIC SYNDROME
WO2014113022A1 (en) * 2013-01-18 2014-07-24 Cymabay Therapeutics, Inc. Dcc mediated coupling for halofenate manufacture

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES251290A1 (es) * 1958-08-21 1960-04-01 Parke Davis & Co Un procedimiento para la producciën de alcohilaminas arilsustituidas

Also Published As

Publication number Publication date
YU185167A (en) 1975-06-30
NL149484B (nl) 1976-05-17
CH512422A (de) 1971-09-15
FR1573841A (member.php) 1969-07-11
FR8372M (member.php) 1971-02-22
AT279590B (de) 1970-03-10
ES345582A1 (es) 1970-02-01
AT282617B (de) 1970-07-10
CS170496B2 (member.php) 1976-08-27
FI48064B (member.php) 1974-02-28
YU32921B (en) 1975-12-31
NO121787B (member.php) 1971-04-13
GB1182007A (en) 1970-02-25
FI48064C (fi) 1974-06-10
DE1643460A1 (de) 1971-01-28
BR6793319D0 (pt) 1973-05-24
NL6712584A (member.php) 1968-04-04
CY650A (en) 1972-07-12
DK120955B (da) 1971-08-09
MY7300079A (en) 1973-12-31
US3517050A (en) 1970-06-23
SE332182B (member.php) 1971-02-01
BE704574A (member.php) 1968-04-02

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