GR3036896T3 - A novel asymmetric synthesis of r and s warfarin and its analogs - Google Patents

A novel asymmetric synthesis of r and s warfarin and its analogs

Info

Publication number
GR3036896T3
GR3036896T3 GR20010401766T GR20010401766T GR3036896T3 GR 3036896 T3 GR3036896 T3 GR 3036896T3 GR 20010401766 T GR20010401766 T GR 20010401766T GR 20010401766 T GR20010401766 T GR 20010401766T GR 3036896 T3 GR3036896 T3 GR 3036896T3
Authority
GR
Greece
Prior art keywords
formula
group
warfarin
analogs
compound
Prior art date
Application number
GR20010401766T
Other languages
English (en)
Inventor
Hui-Yin Li
Andrea Jane Robinson
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of GR3036896T3 publication Critical patent/GR3036896T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GR20010401766T 1995-07-13 2001-10-16 A novel asymmetric synthesis of r and s warfarin and its analogs GR3036896T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US112795P 1995-07-13 1995-07-13
US64712696A 1996-05-09 1996-05-09
PCT/US1996/011489 WO1997003062A1 (en) 1995-07-13 1996-07-10 A novel asymmetric synthesis of r and s warfarin and its analogs

Publications (1)

Publication Number Publication Date
GR3036896T3 true GR3036896T3 (en) 2002-01-31

Family

ID=26668597

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401766T GR3036896T3 (en) 1995-07-13 2001-10-16 A novel asymmetric synthesis of r and s warfarin and its analogs

Country Status (14)

Country Link
EP (1) EP0839142B1 (el)
JP (1) JP4063320B2 (el)
AT (1) ATE205488T1 (el)
AU (1) AU6675696A (el)
CA (1) CA2226752C (el)
DE (1) DE69615200T2 (el)
DK (1) DK0839142T3 (el)
ES (1) ES2163036T3 (el)
GR (1) GR3036896T3 (el)
HR (1) HRP960332A2 (el)
IL (1) IL122924A0 (el)
MX (1) MX9800371A (el)
PT (1) PT839142E (el)
WO (1) WO1997003062A1 (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3064800A (en) * 1999-01-21 2000-08-07 Darwin Discovery Limited The therapeutic use of r-warfarin as anticoagulant
US6673944B2 (en) 2001-02-28 2004-01-06 Taro Pharmaceutical Industries, Ltd. Preparation of warfarin sodium from warfarin acid
US6610862B2 (en) 2001-02-28 2003-08-26 Taro Pharmaceutical Industries Ltd. Preparation of warfarin sodium from warfarin sodium-2-propanol clathrate by solvent expulsion

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171892A (en) * 1991-07-02 1992-12-15 E. I. Du Pont De Nemours And Company Chiral phospholanes via chiral 1,4-diol cyclic sulfates

Also Published As

Publication number Publication date
ATE205488T1 (de) 2001-09-15
ES2163036T3 (es) 2002-01-16
DE69615200T2 (de) 2002-06-06
HRP960332A2 (en) 1998-02-28
DK0839142T3 (da) 2001-10-29
JP4063320B2 (ja) 2008-03-19
IL122924A0 (en) 1998-08-16
AU6675696A (en) 1997-02-10
CA2226752A1 (en) 1997-01-30
JPH11509203A (ja) 1999-08-17
DE69615200D1 (de) 2001-10-18
PT839142E (pt) 2001-12-28
EP0839142B1 (en) 2001-09-12
WO1997003062A1 (en) 1997-01-30
MX9800371A (es) 1998-11-29
EP0839142A1 (en) 1998-05-06
CA2226752C (en) 2002-02-19

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