DK0839142T3 - Hidtil ukendt asymmetrisk syntese af R- og S-warfarin og dens analoger - Google Patents

Hidtil ukendt asymmetrisk syntese af R- og S-warfarin og dens analoger

Info

Publication number
DK0839142T3
DK0839142T3 DK96926709T DK96926709T DK0839142T3 DK 0839142 T3 DK0839142 T3 DK 0839142T3 DK 96926709 T DK96926709 T DK 96926709T DK 96926709 T DK96926709 T DK 96926709T DK 0839142 T3 DK0839142 T3 DK 0839142T3
Authority
DK
Denmark
Prior art keywords
formula
group
warfarin
analogs
asymmetric synthesis
Prior art date
Application number
DK96926709T
Other languages
Danish (da)
English (en)
Inventor
Hui-Yin Li
Andrea Jane Robinson
Original Assignee
Du Pont Pharm Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co
Application granted granted Critical
Publication of DK0839142T3 publication Critical patent/DK0839142T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK96926709T 1995-07-13 1996-07-10 Hidtil ukendt asymmetrisk syntese af R- og S-warfarin og dens analoger DK0839142T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US112795P 1995-07-13 1995-07-13
US64712696A 1996-05-09 1996-05-09
PCT/US1996/011489 WO1997003062A1 (en) 1995-07-13 1996-07-10 A novel asymmetric synthesis of r and s warfarin and its analogs

Publications (1)

Publication Number Publication Date
DK0839142T3 true DK0839142T3 (da) 2001-10-29

Family

ID=26668597

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96926709T DK0839142T3 (da) 1995-07-13 1996-07-10 Hidtil ukendt asymmetrisk syntese af R- og S-warfarin og dens analoger

Country Status (14)

Country Link
EP (1) EP0839142B1 (el)
JP (1) JP4063320B2 (el)
AT (1) ATE205488T1 (el)
AU (1) AU6675696A (el)
CA (1) CA2226752C (el)
DE (1) DE69615200T2 (el)
DK (1) DK0839142T3 (el)
ES (1) ES2163036T3 (el)
GR (1) GR3036896T3 (el)
HR (1) HRP960332A2 (el)
IL (1) IL122924A0 (el)
MX (1) MX9800371A (el)
PT (1) PT839142E (el)
WO (1) WO1997003062A1 (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043003A1 (en) * 1999-01-21 2000-07-27 Darwin Discovery Limited The therapeutic use of r-warfarin as anticoagulant
US6610862B2 (en) 2001-02-28 2003-08-26 Taro Pharmaceutical Industries Ltd. Preparation of warfarin sodium from warfarin sodium-2-propanol clathrate by solvent expulsion
US6673944B2 (en) 2001-02-28 2004-01-06 Taro Pharmaceutical Industries, Ltd. Preparation of warfarin sodium from warfarin acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171892A (en) * 1991-07-02 1992-12-15 E. I. Du Pont De Nemours And Company Chiral phospholanes via chiral 1,4-diol cyclic sulfates

Also Published As

Publication number Publication date
HRP960332A2 (en) 1998-02-28
CA2226752C (en) 2002-02-19
PT839142E (pt) 2001-12-28
DE69615200T2 (de) 2002-06-06
ATE205488T1 (de) 2001-09-15
MX9800371A (es) 1998-11-29
EP0839142A1 (en) 1998-05-06
JPH11509203A (ja) 1999-08-17
EP0839142B1 (en) 2001-09-12
WO1997003062A1 (en) 1997-01-30
ES2163036T3 (es) 2002-01-16
DE69615200D1 (de) 2001-10-18
IL122924A0 (en) 1998-08-16
JP4063320B2 (ja) 2008-03-19
CA2226752A1 (en) 1997-01-30
GR3036896T3 (en) 2002-01-31
AU6675696A (en) 1997-02-10

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