GR3035279T3 - Novel imidazole lipoxygenase inhibitors - Google Patents

Novel imidazole lipoxygenase inhibitors

Info

Publication number
GR3035279T3
GR3035279T3 GR20010400096T GR20010400096T GR3035279T3 GR 3035279 T3 GR3035279 T3 GR 3035279T3 GR 20010400096 T GR20010400096 T GR 20010400096T GR 20010400096 T GR20010400096 T GR 20010400096T GR 3035279 T3 GR3035279 T3 GR 3035279T3
Authority
GR
Greece
Prior art keywords
halo
alkyl
pct
substituted
alkoxy
Prior art date
Application number
GR20010400096T
Other languages
English (en)
Inventor
Takashi Mano
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3035279T3 publication Critical patent/GR3035279T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR20010400096T 1995-09-18 2001-01-22 Novel imidazole lipoxygenase inhibitors GR3035279T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500767 1995-09-18
PCT/IB1996/000744 WO1997011079A1 (en) 1995-09-18 1996-07-24 Novel imidazole lipoxygenase inhibitors

Publications (1)

Publication Number Publication Date
GR3035279T3 true GR3035279T3 (en) 2001-04-30

Family

ID=11004367

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400096T GR3035279T3 (en) 1995-09-18 2001-01-22 Novel imidazole lipoxygenase inhibitors

Country Status (11)

Country Link
US (1) US6037355A (el)
EP (1) EP0863905B1 (el)
JP (1) JP3110049B2 (el)
AT (1) ATE197796T1 (el)
CA (1) CA2232267C (el)
DE (1) DE69611101T2 (el)
DK (1) DK0863905T3 (el)
ES (1) ES2152539T3 (el)
GR (1) GR3035279T3 (el)
PT (1) PT863905E (el)
WO (1) WO1997011079A1 (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344563B1 (en) * 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
RS20090211A (en) 2006-11-27 2010-10-31 Pfizer Products Inc. Pyrazole analogs
CA2931552A1 (en) * 2013-12-19 2015-06-25 Archer Daniels Midland Company Sulfonates of furan-2,5-dimethanol and (tetrahydrofuran-2,5-diyl)dimethanol and derivatives thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911853A1 (en) * 1990-06-21 1992-01-01 Ici Plc Heterocyclene derivatives
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
AU7070494A (en) * 1993-06-02 1994-12-20 Zeneca Limited Bicyclic ether derivatives and their use as 5-lipoxygenase inhibitors
BR9406822A (pt) * 1993-06-14 1996-03-26 Pfizer Inibidores imidazol de lipoxigenase
US5459271A (en) * 1993-07-20 1995-10-17 Merck Frosst Canada, Inc. Arylbicyclooctanes as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
MX9802103A (es) 1998-08-30
DK0863905T3 (da) 2001-01-02
WO1997011079A1 (en) 1997-03-27
US6037355A (en) 2000-03-14
JP3110049B2 (ja) 2000-11-20
ES2152539T3 (es) 2001-02-01
PT863905E (pt) 2001-03-30
EP0863905B1 (en) 2000-11-29
ATE197796T1 (de) 2000-12-15
CA2232267C (en) 2002-06-11
EP0863905A1 (en) 1998-09-16
JPH10511115A (ja) 1998-10-27
DE69611101D1 (de) 2001-01-04
DE69611101T2 (de) 2001-04-05
CA2232267A1 (en) 1997-03-27

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Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees