DE69611101D1 - Imidazol lipoxygenase inhibitoren - Google Patents

Imidazol lipoxygenase inhibitoren

Info

Publication number
DE69611101D1
DE69611101D1 DE69611101T DE69611101T DE69611101D1 DE 69611101 D1 DE69611101 D1 DE 69611101D1 DE 69611101 T DE69611101 T DE 69611101T DE 69611101 T DE69611101 T DE 69611101T DE 69611101 D1 DE69611101 D1 DE 69611101D1
Authority
DE
Germany
Prior art keywords
halo
alkyl
pct
substituted
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69611101T
Other languages
English (en)
Other versions
DE69611101T2 (de
Inventor
Takashi Mano
W Stevens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69611101D1 publication Critical patent/DE69611101D1/de
Publication of DE69611101T2 publication Critical patent/DE69611101T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69611101T 1995-09-18 1996-07-24 Imidazol lipoxygenase inhibitoren Expired - Fee Related DE69611101T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500767 1995-09-18
PCT/IB1996/000744 WO1997011079A1 (en) 1995-09-18 1996-07-24 Novel imidazole lipoxygenase inhibitors

Publications (2)

Publication Number Publication Date
DE69611101D1 true DE69611101D1 (de) 2001-01-04
DE69611101T2 DE69611101T2 (de) 2001-04-05

Family

ID=11004367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69611101T Expired - Fee Related DE69611101T2 (de) 1995-09-18 1996-07-24 Imidazol lipoxygenase inhibitoren

Country Status (11)

Country Link
US (1) US6037355A (de)
EP (1) EP0863905B1 (de)
JP (1) JP3110049B2 (de)
AT (1) ATE197796T1 (de)
CA (1) CA2232267C (de)
DE (1) DE69611101T2 (de)
DK (1) DK0863905T3 (de)
ES (1) ES2152539T3 (de)
GR (1) GR3035279T3 (de)
PT (1) PT863905E (de)
WO (1) WO1997011079A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344563B1 (en) * 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
EP2097407A1 (de) 2006-11-27 2009-09-09 Pfizer Products Inc. Pyrazolanaloga
KR20160098290A (ko) * 2013-12-19 2016-08-18 아처 다니엘 미드랜드 캄파니 푸란-2,5-디메탄올 및 (테트라하이드로푸란-2,5-디일)디메탄올의 설포네이트 및 그 유도체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462830B1 (de) * 1990-06-21 1995-10-18 Zeneca Limited Zyklische Ether-Derivate
IE911853A1 (en) * 1990-06-21 1992-01-01 Ici Plc Heterocyclene derivatives
JPH09504775A (ja) * 1993-06-02 1997-05-13 ゼネカ・リミテッド 二環式エーテル誘導体および５−リポキシゲナーゼ阻害物質としてのそれらの使用
CA2163667C (en) * 1993-06-14 1998-12-15 Rodney W. Stevens Imidazole lipoxygenase inhibitors
US5459271A (en) * 1993-07-20 1995-10-17 Merck Frosst Canada, Inc. Arylbicyclooctanes as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
EP0863905B1 (de) 2000-11-29
CA2232267A1 (en) 1997-03-27
ES2152539T3 (es) 2001-02-01
US6037355A (en) 2000-03-14
GR3035279T3 (en) 2001-04-30
CA2232267C (en) 2002-06-11
WO1997011079A1 (en) 1997-03-27
DK0863905T3 (da) 2001-01-02
DE69611101T2 (de) 2001-04-05
MX9802103A (es) 1998-08-30
JPH10511115A (ja) 1998-10-27
JP3110049B2 (ja) 2000-11-20
EP0863905A1 (de) 1998-09-16
PT863905E (pt) 2001-03-30
ATE197796T1 (de) 2000-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee