GR3025759T3 - COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6 - Google Patents

COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6

Info

Publication number
GR3025759T3
GR3025759T3 GR970403410T GR970403410T GR3025759T3 GR 3025759 T3 GR3025759 T3 GR 3025759T3 GR 970403410 T GR970403410 T GR 970403410T GR 970403410 T GR970403410 T GR 970403410T GR 3025759 T3 GR3025759 T3 GR 3025759T3
Authority
GR
Greece
Prior art keywords
cell
epitope
cd44v6
cells
hermes
Prior art date
Application number
GR970403410T
Other languages
English (en)
Inventor
Sirpa Jalkanen
Marko Salmi
Original Assignee
Biotie Therapies Jalkanen Sirp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22141703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3025759(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotie Therapies Jalkanen Sirp filed Critical Biotie Therapies Jalkanen Sirp
Publication of GR3025759T3 publication Critical patent/GR3025759T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70585—CD44
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GR970403410T 1993-06-18 1997-12-23 COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6 GR3025759T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7806393A 1993-06-18 1993-06-18
PCT/FI1994/000264 WO1995000658A1 (en) 1993-06-18 1994-06-16 COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6

Publications (1)

Publication Number Publication Date
GR3025759T3 true GR3025759T3 (en) 1998-03-31

Family

ID=22141703

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970403410T GR3025759T3 (en) 1993-06-18 1997-12-23 COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6

Country Status (13)

Country Link
US (1) US5616468A (el)
EP (1) EP0703989B1 (el)
JP (1) JPH08511419A (el)
AT (1) ATE159953T1 (el)
AU (1) AU678487B2 (el)
CA (1) CA2165461A1 (el)
DE (1) DE69406664T2 (el)
DK (1) DK0703989T3 (el)
ES (1) ES2110764T3 (el)
GR (1) GR3025759T3 (el)
IL (1) IL110070A0 (el)
WO (1) WO1995000658A1 (el)
ZA (1) ZA944383B (el)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4134982A1 (de) * 1991-10-23 1993-04-29 Kernforschungsz Karlsruhe Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression
KR100268772B1 (ko) * 1992-06-09 2000-10-16 마르쿠 잘카넨 인간에 있어서 임파구 결합을 매개하는 신규 내피 세포 분자
UA58482C2 (uk) * 1994-06-08 2003-08-15 Бьорінгер Інгельхайм Інтернаціональ Гмбх Моноклональне антитіло vff-18 проти сd44v6 і його фрагменти
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
DE19545472A1 (de) * 1995-12-06 1997-06-12 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Plattenepithelkarzinomen
UY24389A1 (es) * 1995-12-06 2001-10-25 Karlsruhe Forschzent Composición farmacéutica para el tratamiento de carcinoma de epitelio plano
DE19653607A1 (de) 1996-12-20 1998-06-25 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen
US8048416B2 (en) 1999-10-08 2011-11-01 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7947496B2 (en) 1999-10-08 2011-05-24 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7189397B2 (en) * 1999-10-08 2007-03-13 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20090004103A1 (en) * 1999-10-08 2009-01-01 Young David S F Cytotoxicity mediation of cells evidencing surface expression of CD44
US8071072B2 (en) 1999-10-08 2011-12-06 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20050100542A1 (en) * 1999-10-08 2005-05-12 Young David S. Cytotoxicity mediation of cells evidencing surface expression of CD44
US6972324B2 (en) * 2001-05-18 2005-12-06 Boehringer Ingelheim Pharmaceuticals, Inc. Antibodies specific for CD44v6
US8980568B2 (en) 2001-10-11 2015-03-17 Aviva Biosciences Corporation Methods and compositions for detecting non-hematopoietic cells from a blood sample
US8986944B2 (en) 2001-10-11 2015-03-24 Aviva Biosciences Corporation Methods and compositions for separating rare cells from fluid samples
US20040110933A1 (en) * 2002-09-13 2004-06-10 Dyax Corporation CD44-binding ligands
ES2533002T3 (es) * 2004-03-10 2015-04-06 Creighton University Receptores estrogénicos y métodos de uso
WO2005095987A2 (en) * 2004-03-26 2005-10-13 University Of Miami Salivary soluble cd44: a molecular marker for head and neck cancer
US20080057505A1 (en) * 2006-07-14 2008-03-06 Ping Lin Methods and compositions for detecting rare cells from a biological sample
WO2008008515A2 (en) * 2006-07-14 2008-01-17 Aviva Biosciences Corporation Methods and compositions for detecting rare cells from a biological sample
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
EA201391387A1 (ru) * 2011-03-24 2014-01-30 Неурим Фармасьютикалс (1991) Лтд. Нейропротекторные пептиды
JP6671363B2 (ja) 2014-07-15 2020-03-25 イッサム リサーチ ディヴェロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミティッド Ｃｄ４４の単離されたポリペプチドおよびその使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014510A1 (de) 1990-05-07 1991-11-14 Kernforschungsz Karlsruhe Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie
DE4134982A1 (de) 1991-10-23 1993-04-29 Kernforschungsz Karlsruhe Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression

Also Published As

Publication number Publication date
ES2110764T3 (es) 1998-02-16
JPH08511419A (ja) 1996-12-03
AU678487B2 (en) 1997-05-29
DE69406664D1 (de) 1997-12-11
DK0703989T3 (da) 1998-02-09
AU6972694A (en) 1995-01-17
IL110070A0 (en) 1994-10-07
ATE159953T1 (de) 1997-11-15
US5616468A (en) 1997-04-01
WO1995000658A1 (en) 1995-01-05
EP0703989B1 (en) 1997-11-05
EP0703989A1 (en) 1996-04-03
CA2165461A1 (en) 1995-01-05
DE69406664T2 (de) 1998-06-04
ZA944383B (en) 1995-03-03

Similar Documents

Publication Publication Date Title
ZA944383B (en) Compositions and diagnostic methods using monoclonal antibodies against CD44v6
Bukovský et al. The localization of Thy-1.1, MRC OX 2 and Ia antigens in the rat ovary and fallopian tube.
Meigel et al. Dermal architecture and collagen type distribution
Heyderman et al. A new monoclonal antibody to epithelial membrane antigen (EMA)-E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2
Natali et al. Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions
Weiss et al. An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function
Bardin et al. S‐Endo 1, a pan‐endothelial monoclonal antibody recognizing a novel human endothelial antigen
Ellis et al. A monoclonal antibody, NCRC‐11, raised to human breast carcinoma. 1. Production and immunohistological characterization
Hamilton et al. Characterization of a human endocrine tissue and tumor-associated Ewing's sarcoma antigen
Bordessoule et al. Immunohistological patterns of myeloid antigens: tissue distribution of CD13, CD14, CD16, CD31, CD36, CD65, CD66 and CD67
Jungbluth et al. T311—an anti-tyrosinase monoclonal antibody for the detection of melanocytic lesions in paraffin embedded tissues
Cagnano et al. Expression of ligands to NKp46 in benign and malignant melanocytes
Rochaix et al. PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen
Posnett et al. A membrane antigen (HC1) selectively present on hairy cell leukemia cells, endothelial cells, and epidermal basal cells.
Lifschitz-Mercer et al. Epidermoid cyst of the spleen: a cytokeratin profile with comparison to other squamous epithelia
Lohi et al. Expression of type IV collagen α1 (IV)–α6 (IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas
Georgolios et al. THE ROLE OF CD�� ADHESION MOLECULE IN ORAL CAVITY CANCER
Fujimura et al. Aminopeptidase A expression in cervical neoplasia and its relationship to neoplastic transformation and progression
Tatemoto et al. Immunohistochemical observations on binding of monoclonal antibody to epithelial membrane antigen in epithelial tumors of the oral cavity and skin
Castagna et al. Mammary cancer antigen recognized by monoclonal antibody B72. 3 in apocrine metaplasia of the human breast
Labat-Robert et al. Modifications of fibronectin in age-related diseases: diabetes and cancer
Goepel et al. Tenascin—a marker for the malignant potential of preinvasive breast cancers
Schaider et al. CD44 and variants in melanocytic skin neoplasms
Toto et al. Product definition of pleomorphic adenoma of minor salivary glands
Kobayashi et al. A case of Bednar tumor