GR3023858T3 - Oligoribonucleotide- and ribozyme-analoguer with terminal 3',3'- and 5',5'-bonds respectively - Google Patents

Oligoribonucleotide- and ribozyme-analoguer with terminal 3',3'- and 5',5'-bonds respectively

Info

Publication number
GR3023858T3
GR3023858T3 GR970401499T GR970401499T GR3023858T3 GR 3023858 T3 GR3023858 T3 GR 3023858T3 GR 970401499 T GR970401499 T GR 970401499T GR 970401499 T GR970401499 T GR 970401499T GR 3023858 T3 GR3023858 T3 GR 3023858T3
Authority
GR
Greece
Prior art keywords
terminal
oligoribonucleotide
analoguer
ribozyme
bonds respectively
Prior art date
Application number
GR970401499T
Other languages
English (en)
Inventor
H Prof Dr Seliger
Flavio Ramalho Dr Ortigao
Hannelore Roesch
Rudi Roesch
Bernd Krist
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6468696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3023858(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3023858T3 publication Critical patent/GR3023858T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
GR970401499T 1992-09-24 1997-06-20 Oligoribonucleotide- and ribozyme-analoguer with terminal 3',3'- and 5',5'-bonds respectively GR3023858T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4231949 1992-09-24

Publications (1)

Publication Number Publication Date
GR3023858T3 true GR3023858T3 (en) 1997-09-30

Family

ID=6468696

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970401499T GR3023858T3 (en) 1992-09-24 1997-06-20 Oligoribonucleotide- and ribozyme-analoguer with terminal 3',3'- and 5',5'-bonds respectively

Country Status (14)

Country Link
US (1) US6420546B1 (el)
EP (1) EP0593901B2 (el)
JP (1) JP3653102B2 (el)
AT (1) ATE151773T1 (el)
AU (1) AU665113B2 (el)
CA (1) CA2106819C (el)
DE (1) DE59306170D1 (el)
DK (1) DK0593901T3 (el)
ES (1) ES2103408T3 (el)
FI (1) FI115400B (el)
GR (1) GR3023858T3 (el)
HU (1) HU219638B (el)
NO (1) NO307656B1 (el)
NZ (1) NZ248739A (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646042A (en) * 1992-08-26 1997-07-08 Ribozyme Pharmaceuticals, Inc. C-myb targeted ribozymes
US5998203A (en) 1996-04-16 1999-12-07 Ribozyme Pharmaceuticals, Inc. Enzymatic nucleic acids containing 5'-and/or 3'-cap structures
ATE267247T1 (de) * 1996-05-24 2004-06-15 Aventis Pharma Gmbh Reagenz und verfahren zur inhibierung der n-ras expression
US7572582B2 (en) 1997-09-12 2009-08-11 Exiqon A/S Oligonucleotide analogues
JP2003525017A (ja) * 1998-04-20 2003-08-26 リボザイム・ファーマシューティカルズ・インコーポレーテッド 遺伝子発現を調節しうる新規な化学組成を有する核酸分子
DE19935303A1 (de) 1999-07-28 2001-02-08 Aventis Pharma Gmbh Oligonukleotide zur Inhibierung der Expression von humanem eg5
AU2001296305B2 (en) 2000-09-26 2007-12-06 Duke University RNA aptamers and methods for identifying the same
AU2002312059B2 (en) 2001-05-25 2009-01-15 Duke University Modulators of pharmacological agents
KR101147147B1 (ko) 2004-04-01 2012-05-25 머크 샤프 앤드 돔 코포레이션 Rna 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
AU2005238490B2 (en) 2004-04-22 2010-11-18 Tobira Therapeutics, Inc. Improved modulators of coagulation factors
US7923207B2 (en) 2004-11-22 2011-04-12 Dharmacon, Inc. Apparatus and system having dry gene silencing pools
US20060166234A1 (en) 2004-11-22 2006-07-27 Barbara Robertson Apparatus and system having dry control gene silencing compositions
US7935811B2 (en) 2004-11-22 2011-05-03 Dharmacon, Inc. Apparatus and system having dry gene silencing compositions
EP1820804A1 (en) * 2006-02-20 2007-08-22 Humboldt-Universität zu Berlin Lipidated oligonucleotides
US8252755B2 (en) 2006-09-22 2012-08-28 Dharmacon, Inc. Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
US7845686B2 (en) * 2007-12-17 2010-12-07 S & B Technical Products, Inc. Restrained pipe joining system for plastic pipe
US8188060B2 (en) 2008-02-11 2012-05-29 Dharmacon, Inc. Duplex oligonucleotides with enhanced functionality in gene regulation
EP2781523A1 (en) 2013-03-18 2014-09-24 Miltenyi Biotec GmbH Lipophilic oligonucleotide analogs
WO2019006455A1 (en) 2017-06-30 2019-01-03 Solstice Biologics, Ltd. AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF
US11104941B2 (en) * 2018-09-28 2021-08-31 Bioo Scientific Corporation 5′ adapter comprising an internal 5′-5′ linkage

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3916871A1 (de) * 1989-05-24 1990-11-29 Boehringer Mannheim Gmbh Modifiziertes phosphoramidit-verfahren zur herstellung von modifizierten nukleinsaeuren
US5399676A (en) * 1989-10-23 1995-03-21 Gilead Sciences Oligonucleotides with inverted polarity
DK0464638T3 (da) * 1990-07-02 1997-10-13 Hoechst Ag Oligonukleotidanaloge med terminale 3-3- eller 5-5-internukleotidbindinger.
US5672697A (en) * 1991-02-08 1997-09-30 Gilead Sciences, Inc. Nucleoside 5'-methylene phosphonates
FI115214B (fi) * 1992-01-22 2005-03-31 Hoechst Ag Menetelmä oligonukleotidianalogien valmistamiseksi ja niiden käyttö
US5646261A (en) * 1992-01-22 1997-07-08 Hoechst Aktiengesellschaft 3'-derivatized oligonucleotide analogs with non-nucleotidic groupings, their preparation and use

Also Published As

Publication number Publication date
NZ248739A (en) 1995-08-28
JP3653102B2 (ja) 2005-05-25
DK0593901T3 (da) 1997-10-27
ATE151773T1 (de) 1997-05-15
CA2106819C (en) 2007-04-17
AU665113B2 (en) 1995-12-14
AU4755193A (en) 1994-03-31
NO933397D0 (no) 1993-09-23
HU9302697D0 (en) 1993-12-28
NO307656B1 (no) 2000-05-08
FI115400B (fi) 2005-04-29
CA2106819A1 (en) 1994-03-25
FI934154A0 (fi) 1993-09-22
EP0593901A2 (de) 1994-04-27
FI934154A (fi) 1994-03-25
NO933397L (no) 1994-03-25
ES2103408T3 (es) 1997-09-16
JPH06189753A (ja) 1994-07-12
HU219638B (hu) 2001-06-28
EP0593901B2 (de) 2008-04-09
EP0593901A3 (en) 1994-09-28
EP0593901B1 (de) 1997-04-16
DE59306170D1 (de) 1997-05-22
US6420546B1 (en) 2002-07-16
HUT66458A (en) 1994-11-28

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