GR3002593T3 - Process for intermediates to leukotriene antagonists - Google Patents

Process for intermediates to leukotriene antagonists

Info

Publication number
GR3002593T3
GR3002593T3 GR91401212T GR910401212T GR3002593T3 GR 3002593 T3 GR3002593 T3 GR 3002593T3 GR 91401212 T GR91401212 T GR 91401212T GR 910401212 T GR910401212 T GR 910401212T GR 3002593 T3 GR3002593 T3 GR 3002593T3
Authority
GR
Greece
Prior art keywords
intermediates
leukotriene antagonists
leukotriene
antagonists
dihydroxyphenones
Prior art date
Application number
GR91401212T
Other languages
English (en)
Inventor
Winston Stanley Marshall
Sandra Kay Sigmund
Celia Ann Whitesitt
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3002593T3 publication Critical patent/GR3002593T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR91401212T 1987-06-19 1991-08-22 Process for intermediates to leukotriene antagonists GR3002593T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6490087A 1987-06-19 1987-06-19

Publications (1)

Publication Number Publication Date
GR3002593T3 true GR3002593T3 (en) 1993-01-25

Family

ID=22058969

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91401212T GR3002593T3 (en) 1987-06-19 1991-08-22 Process for intermediates to leukotriene antagonists

Country Status (10)

Country Link
EP (1) EP0295882B1 (el)
JP (1) JPS6416740A (el)
KR (1) KR960002601B1 (el)
AT (1) ATE66453T1 (el)
CA (1) CA1300170C (el)
DE (1) DE3864324D1 (el)
ES (1) ES2029019T3 (el)
GR (1) GR3002593T3 (el)
HU (1) HU202814B (el)
IL (1) IL86748A (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100383215B1 (ko) * 2000-09-25 2003-05-12 한국생명공학연구원 신균주 ｍｔ90049(ｋｃｔｃ 18043ｐ)와 이 균주로부터생산된 신규 화합물과 신규 화합물의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
EP0167286A1 (en) * 1984-06-04 1986-01-08 Celanese Corporation Process for producing 4-hydroxyacetophenone

Also Published As

Publication number Publication date
ATE66453T1 (de) 1991-09-15
KR890000390A (ko) 1989-03-14
EP0295882B1 (en) 1991-08-21
ES2029019T3 (es) 1992-07-16
JPS6416740A (en) 1989-01-20
KR960002601B1 (ko) 1996-02-23
DE3864324D1 (de) 1991-09-26
IL86748A (en) 1992-06-21
IL86748A0 (en) 1988-11-30
CA1300170C (en) 1992-05-05
HUT47235A (en) 1989-02-28
EP0295882A1 (en) 1988-12-21
HU202814B (en) 1991-04-29

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