GR26072B - METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE. - Google Patents

METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE.

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Publication number
GR26072B
GR26072B GR610126072A GR610126072A GR26072B GR 26072 B GR26072 B GR 26072B GR 610126072 A GR610126072 A GR 610126072A GR 610126072 A GR610126072 A GR 610126072A GR 26072 B GR26072 B GR 26072B
Authority
GR
Greece
Prior art keywords
benzodiazepine
preparation
fluoresced
products
substituent
Prior art date
Application number
GR610126072A
Other languages
Greek (el)
Original Assignee
F. Hoffmann - La Roche Und Co Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann - La Roche Und Co Aktiengesellschaft filed Critical F. Hoffmann - La Roche Und Co Aktiengesellschaft
Priority to GR610126072A priority Critical patent/GR26072B/en
Publication of GR26072B publication Critical patent/GR26072B/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

έθοδος διά την παρασκευήν φθοριούχων παραγώγων της βενζοδιαζεπίνης διακρινομένη έκ τούτου, ότι έν αλογονίδιον του γενικού τύπου (Ι) είς τον οποίον τοΧ δηλεί αλογονον, το R1 είναι υδρογόνον ή αλκύλιον, και ο είς έκ των διά R3 σημειουμένων υποκαταστάστων δηλοί μίαν τροφθορομεθυλικήν ομάδα, ο δέν άλλος υποκαταστάτης είναι υδρογόνον, φέρομεν είς αντίδρασιν μετ'αμμωνίας ή μιάς πρωτοταγούς αμίνης και,εάν είναι επιθυμητόν, το λαμβανόμενον προιόν τηςαντιδράσεως μετατρέπομεν τη βοηθεία ενός οξέος είς έν διά προσθήκης οξέος άλας. Process for the preparation of benzodiazepine fluorinated derivatives, characterized in that a halide of general formula (I) in which X denotes halogen, R1 is hydrogen or alkyl, and one of the R3-labeled substituents denotes a substituent No other substituent is hydrogen, reacted with ammonia or a primary amine and, if desired, the reaction product obtained is converted, with the aid of an acid, to an acid addition salt.

GR610126072A 1961-01-12 1961-01-12 METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE. GR26072B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR610126072A GR26072B (en) 1961-01-12 1961-01-12 METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR610126072A GR26072B (en) 1961-01-12 1961-01-12 METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE.

Publications (1)

Publication Number Publication Date
GR26072B true GR26072B (en) 1964-05-14

Family

ID=36865005

Family Applications (1)

Application Number Title Priority Date Filing Date
GR610126072A GR26072B (en) 1961-01-12 1961-01-12 METHOD FOR THE PREPARATION OF FLUORESCED PRODUCTS OF BENZODIAZEPINE.

Country Status (1)

Country Link
GR (1) GR26072B (en)

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