GR1000083B - Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια. - Google Patents

Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια.

Info

Publication number
GR1000083B
GR1000083B GR880100104A GR880100104A GR1000083B GR 1000083 B GR1000083 B GR 1000083B GR 880100104 A GR880100104 A GR 880100104A GR 880100104 A GR880100104 A GR 880100104A GR 1000083 B GR1000083 B GR 1000083B
Authority
GR
Greece
Prior art keywords
peptides
mycetobacterial
recompositions
products derived
proteins
Prior art date
Application number
GR880100104A
Other languages
English (en)
Other versions
GR880100104A (en
Inventor
Richard Houghten
Thomas Shinnick
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of GR880100104A publication Critical patent/GR880100104A/el
Publication of GR1000083B publication Critical patent/GR1000083B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Περιγράφονται εξ ανασυνδυασμού πρωτείναι των 540 ριζών αμινοξέων και των 517 ριζών αμινοξέων κωδικοποιούμεναι υπό του γενόματος του MYCOBACTERIUM TUBERCULOSIS. Ως επίσης και φορείς δια τον πολλαπλασιασμόν/αναπαραγωγήν της αλληλουχίας DNA αυτών και έκφρασιν των πρωτεϊνών. Περιγράφονται επίσης πεπτίδια αντιστοιχούντα ουσιαστικώς εις την αλληλουχίαν των πρωτεϊνών τούτων και μέθοδοι χρησιμοποιήσεως των, ως επίσης και πολυμερή περιέχοντα πενταπεπτίδια πρωτείνης 517 ως επαναλαμβανομένας μονάδας. ω
GR880100104A 1987-02-26 1988-02-25 Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια. GR1000083B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/019,529 US4952395A (en) 1987-02-26 1987-02-26 Mycobacterial recombinants and peptides

Publications (2)

Publication Number Publication Date
GR880100104A GR880100104A (en) 1988-12-16
GR1000083B true GR1000083B (el) 1990-11-29

Family

ID=21793686

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100104A GR1000083B (el) 1987-02-26 1988-02-25 Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια.

Country Status (8)

Country Link
US (1) US4952395A (el)
CA (1) CA1340423C (el)
ES (1) ES2009238A6 (el)
GR (1) GR1000083B (el)
NZ (1) NZ223632A (el)
PT (1) PT86838B (el)
WO (1) WO1988006591A1 (el)
ZA (1) ZA881344B (el)

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US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus
FR2645878B1 (fr) * 1989-04-17 1994-02-25 Institut Nal Sante Recherc Medic Sequences nucleotidiques d'actinomycetales, applications a la synthese ou a la detection d'acides nucleiques, produits d'expression de ces sequences et application en tant que compositions immunogenes
SE9001105D0 (sv) * 1990-03-27 1990-03-27 Astra Ab New methods foer diagnosis of tuberculosis
US5776693A (en) * 1990-06-08 1998-07-07 Institut Pasteur Specific detection of the mycobacterium tuberculosis
GB9111291D0 (en) * 1991-05-24 1991-07-17 Medical Res Council Diagnostic peptides
FR2694754B1 (fr) * 1992-08-12 1994-09-16 Bio Merieux Fragments d'ADN de mycobactéries, amorces d'amplification, sondes d'hybridation, réactifs et procédé de détection de détection de mycobactéries.
US6991797B2 (en) * 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US5955077A (en) * 1993-07-02 1999-09-21 Statens Seruminstitut Tuberculosis vaccine
US7300660B2 (en) * 1993-11-23 2007-11-27 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
CN1103781C (zh) 1993-11-23 2003-03-26 加利福尼亚大学 丰富的细胞外产物和其生产与使用方法
US6752993B1 (en) 1993-11-23 2004-06-22 The Regents Of The University Of California Abundant extracellular product vaccines and methods for their production and use
PT751957E (pt) * 1994-03-21 2004-07-30 Univ Utrecht Fragmentos peptidicos de proteinas de stress microbianas e composicao farmaceutica a base destes fragmentos para o tratamento e a prevencao de doencas inflamatorias
US5874405A (en) * 1994-12-16 1999-02-23 Birnbaum; Gary Heat shock protein peptides that share sequences with cyclic nucleotide phosphodiesterase and methods for modulating autoimmune central nervous system disease
US6458366B1 (en) * 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6338852B1 (en) 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6013660A (en) * 1996-10-02 2000-01-11 The Regents Of The University Of California Externally targeted prophylactic and chemotherapeutic method and agents
US7157089B1 (en) 1996-11-26 2007-01-02 Stressgen Biotechnologies Corporation Immune responses using compositions containing stress proteins
US6982085B2 (en) * 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
US6613881B1 (en) 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
ATE327259T1 (de) 1997-08-05 2006-06-15 Stressgen Biotechnologies Corp Immunantwort gegen hpv antigene hervorgerufen von zusammensetzungen die ein hpv antigen und ein stressprotein enthalten oder einem expressionsvektor fähig zur expression dieser proteine
US20040013685A1 (en) * 1997-11-10 2004-01-22 Peter Andersen Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US6497880B1 (en) 1998-12-08 2002-12-24 Stressgen Biotechnologies Corporation Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6495347B1 (en) 1999-07-08 2002-12-17 Stressgen Biotechnologies Corporation Induction of a Th1-like response in vitro
AU7033400A (en) * 1999-08-30 2001-03-26 Jehad Mikhaiel Charo Induction of cytotoxic t lymphocyte response by hla class ia restricted epitopesof mycobacterial heat shock protein 65
US7632803B2 (en) 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US7592304B2 (en) 1999-10-01 2009-09-22 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
CA2386841A1 (en) * 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
ATE438408T1 (de) 2000-01-14 2009-08-15 Whitehead Biomedical Inst Induktion zytotoxischer lymphozyten durch hitzeschockprotein-fusionsproteine hängt von der atp-bindungsdomäne in hsp ab und is cd4+ unabhängig
AU2001241738A1 (en) * 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
ATE526994T1 (de) * 2000-06-20 2011-10-15 Corixa Corp Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten
PT1296711E (pt) 2000-06-26 2006-08-31 Stressgen Biotechnologies Corp E7 de vph para o tratamento do virus do papiloma humano
AU2001271963A1 (en) * 2000-07-10 2002-01-21 Colorado State University Research Foundation Mid-life vaccine and methods for boosting anti-mycobacterial immunity
WO2002048175A2 (en) * 2000-12-13 2002-06-20 Argonex Pharmaceuticals Mhc class i associated peptides for prevention and treatment of tuberculosis
WO2002062959A2 (en) 2001-02-05 2002-08-15 Stressgen Biotechnologies Corp. Hepatitis b virus treatment
WO2003070187A2 (en) 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US20060142251A1 (en) * 2002-11-15 2006-06-29 Gunther Harth Anti-microbial agents derived from methionine sulfoximine analogues
PL239045B1 (pl) * 2018-01-09 2021-11-02 Inst Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk Epitop specyficzny dla zakaźnych Streptococcus agalactiae oraz sposób wykrywania zakażenia pacjenta szczepem Streptococcus agalactiae

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US3853833A (en) * 1971-04-27 1974-12-10 Hormone Res Foundation Synthetic human growth-promoting and lactogenic hormones and method of producing same
US4575484A (en) * 1980-05-05 1986-03-11 Montefiore Medical Center, Inc. Binding assay for the detection of mycobacteria
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US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
GB8404280D0 (en) * 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4689397A (en) * 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
NL8701163A (nl) * 1986-09-09 1988-04-05 Nederlanden Staat Gebruik van een peptide voor de bereiding van preparaten voor het verlichten, het behandelen en de diagnose van autoimmuunziekten, in het bijzonder arthritische toestanden, verbindingen die met dit peptide verwant zijn, alsmede farmaceutische en diagnostische preparaten en testkits.
AU1548388A (en) * 1987-02-02 1988-08-24 Whitehead Institute For Biomedical Research Mycobacterium tuberculosis genes and encoding protein antigens

Also Published As

Publication number Publication date
US4952395A (en) 1990-08-28
ZA881344B (en) 1988-08-26
ES2009238A6 (es) 1989-09-16
WO1988006591A1 (en) 1988-09-07
CA1340423C (en) 1999-03-09
PT86838A (pt) 1988-03-01
PT86838B (pt) 1992-05-29
NZ223632A (en) 1991-03-26
GR880100104A (en) 1988-12-16

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