GR1000083B - Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια. - Google Patents
Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια.Info
- Publication number
- GR1000083B GR1000083B GR880100104A GR880100104A GR1000083B GR 1000083 B GR1000083 B GR 1000083B GR 880100104 A GR880100104 A GR 880100104A GR 880100104 A GR880100104 A GR 880100104A GR 1000083 B GR1000083 B GR 1000083B
- Authority
- GR
- Greece
- Prior art keywords
- peptides
- mycetobacterial
- recompositions
- products derived
- proteins
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- -1 radical amino acids Chemical class 0.000 abstract 2
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Περιγράφονται εξ ανασυνδυασμού πρωτείναι των 540 ριζών αμινοξέων και των 517 ριζών αμινοξέων κωδικοποιούμεναι υπό του γενόματος του MYCOBACTERIUM TUBERCULOSIS. Ως επίσης και φορείς δια τον πολλαπλασιασμόν/αναπαραγωγήν της αλληλουχίας DNA αυτών και έκφρασιν των πρωτεϊνών. Περιγράφονται επίσης πεπτίδια αντιστοιχούντα ουσιαστικώς εις την αλληλουχίαν των πρωτεϊνών τούτων και μέθοδοι χρησιμοποιήσεως των, ως επίσης και πολυμερή περιέχοντα πενταπεπτίδια πρωτείνης 517 ως επαναλαμβανομένας μονάδας. ω
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/019,529 US4952395A (en) | 1987-02-26 | 1987-02-26 | Mycobacterial recombinants and peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
GR880100104A GR880100104A (en) | 1988-12-16 |
GR1000083B true GR1000083B (el) | 1990-11-29 |
Family
ID=21793686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR880100104A GR1000083B (el) | 1987-02-26 | 1988-02-25 | Μυκητοβακτηριακα προιοντα εξ ανασυνθεσεως και πεπτιδια. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4952395A (el) |
CA (1) | CA1340423C (el) |
ES (1) | ES2009238A6 (el) |
GR (1) | GR1000083B (el) |
NZ (1) | NZ223632A (el) |
PT (1) | PT86838B (el) |
WO (1) | WO1988006591A1 (el) |
ZA (1) | ZA881344B (el) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8703107A (nl) * | 1987-12-22 | 1989-07-17 | Nederlanden Staat | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
WO1994029459A1 (en) | 1993-06-04 | 1994-12-22 | Whitehead Institute For Biomedical Research | Stress proteins and uses therefor |
DE68924162T2 (de) * | 1988-06-15 | 1996-04-25 | Whitehead Biomedical Inst | Stressproteine und verwendungen dafür. |
ZA898883B (en) * | 1988-11-25 | 1990-08-29 | Akzo Nv | Anti-hcg antibodies |
US5114844A (en) * | 1989-03-14 | 1992-05-19 | Yeda Research And Development Co., Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus |
FR2645878B1 (fr) * | 1989-04-17 | 1994-02-25 | Institut Nal Sante Recherc Medic | Sequences nucleotidiques d'actinomycetales, applications a la synthese ou a la detection d'acides nucleiques, produits d'expression de ces sequences et application en tant que compositions immunogenes |
SE9001105D0 (sv) * | 1990-03-27 | 1990-03-27 | Astra Ab | New methods foer diagnosis of tuberculosis |
US5776693A (en) * | 1990-06-08 | 1998-07-07 | Institut Pasteur | Specific detection of the mycobacterium tuberculosis |
GB9111291D0 (en) * | 1991-05-24 | 1991-07-17 | Medical Res Council | Diagnostic peptides |
FR2694754B1 (fr) * | 1992-08-12 | 1994-09-16 | Bio Merieux | Fragments d'ADN de mycobactéries, amorces d'amplification, sondes d'hybridation, réactifs et procédé de détection de détection de mycobactéries. |
US6991797B2 (en) * | 1993-07-02 | 2006-01-31 | Statens Serum Institut | M. tuberculosis antigens |
US5955077A (en) * | 1993-07-02 | 1999-09-21 | Statens Seruminstitut | Tuberculosis vaccine |
US7300660B2 (en) * | 1993-11-23 | 2007-11-27 | The Regents Of The University Of California | Abundant extracellular products and methods for their production and use |
CN1103781C (zh) | 1993-11-23 | 2003-03-26 | 加利福尼亚大学 | 丰富的细胞外产物和其生产与使用方法 |
US6752993B1 (en) | 1993-11-23 | 2004-06-22 | The Regents Of The University Of California | Abundant extracellular product vaccines and methods for their production and use |
PT751957E (pt) * | 1994-03-21 | 2004-07-30 | Univ Utrecht | Fragmentos peptidicos de proteinas de stress microbianas e composicao farmaceutica a base destes fragmentos para o tratamento e a prevencao de doencas inflamatorias |
US5874405A (en) * | 1994-12-16 | 1999-02-23 | Birnbaum; Gary | Heat shock protein peptides that share sequences with cyclic nucleotide phosphodiesterase and methods for modulating autoimmune central nervous system disease |
US6458366B1 (en) * | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
US6290969B1 (en) | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6592877B1 (en) * | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6338852B1 (en) | 1995-09-01 | 2002-01-15 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
US6013660A (en) * | 1996-10-02 | 2000-01-11 | The Regents Of The University Of California | Externally targeted prophylactic and chemotherapeutic method and agents |
US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
US6982085B2 (en) * | 1997-04-02 | 2006-01-03 | Statens Serum Institut | TB diagnostic based on antigens from M. tuberculosis |
US7037510B2 (en) | 1997-04-18 | 2006-05-02 | Statens Serum Institut | Hybrids of M. tuberculosis antigens |
US6555653B2 (en) | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
US6613881B1 (en) | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
ATE327259T1 (de) | 1997-08-05 | 2006-06-15 | Stressgen Biotechnologies Corp | Immunantwort gegen hpv antigene hervorgerufen von zusammensetzungen die ein hpv antigen und ein stressprotein enthalten oder einem expressionsvektor fähig zur expression dieser proteine |
US20040013685A1 (en) * | 1997-11-10 | 2004-01-22 | Peter Andersen | Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis |
US6497880B1 (en) | 1998-12-08 | 2002-12-24 | Stressgen Biotechnologies Corporation | Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus |
US6465633B1 (en) | 1998-12-24 | 2002-10-15 | Corixa Corporation | Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis |
US8143386B2 (en) * | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
US6495347B1 (en) | 1999-07-08 | 2002-12-17 | Stressgen Biotechnologies Corporation | Induction of a Th1-like response in vitro |
AU7033400A (en) * | 1999-08-30 | 2001-03-26 | Jehad Mikhaiel Charo | Induction of cytotoxic t lymphocyte response by hla class ia restricted epitopesof mycobacterial heat shock protein 65 |
US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
CA2386841A1 (en) * | 1999-10-07 | 2001-04-12 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
ATE438408T1 (de) | 2000-01-14 | 2009-08-15 | Whitehead Biomedical Inst | Induktion zytotoxischer lymphozyten durch hitzeschockprotein-fusionsproteine hängt von der atp-bindungsdomäne in hsp ab und is cd4+ unabhängig |
AU2001241738A1 (en) * | 2000-02-25 | 2001-09-03 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
ATE526994T1 (de) * | 2000-06-20 | 2011-10-15 | Corixa Corp | Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten |
PT1296711E (pt) | 2000-06-26 | 2006-08-31 | Stressgen Biotechnologies Corp | E7 de vph para o tratamento do virus do papiloma humano |
AU2001271963A1 (en) * | 2000-07-10 | 2002-01-21 | Colorado State University Research Foundation | Mid-life vaccine and methods for boosting anti-mycobacterial immunity |
WO2002048175A2 (en) * | 2000-12-13 | 2002-06-20 | Argonex Pharmaceuticals | Mhc class i associated peptides for prevention and treatment of tuberculosis |
WO2002062959A2 (en) | 2001-02-05 | 2002-08-15 | Stressgen Biotechnologies Corp. | Hepatitis b virus treatment |
WO2003070187A2 (en) | 2002-02-15 | 2003-08-28 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
US20060142251A1 (en) * | 2002-11-15 | 2006-06-29 | Gunther Harth | Anti-microbial agents derived from methionine sulfoximine analogues |
PL239045B1 (pl) * | 2018-01-09 | 2021-11-02 | Inst Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk | Epitop specyficzny dla zakaźnych Streptococcus agalactiae oraz sposób wykrywania zakażenia pacjenta szczepem Streptococcus agalactiae |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3853833A (en) * | 1971-04-27 | 1974-12-10 | Hormone Res Foundation | Synthetic human growth-promoting and lactogenic hormones and method of producing same |
US4575484A (en) * | 1980-05-05 | 1986-03-11 | Montefiore Medical Center, Inc. | Binding assay for the detection of mycobacteria |
US4489158A (en) * | 1980-05-05 | 1984-12-18 | Montefiore Hospital And Medical Center, Inc. | Binding assay for the detection of mycobacteria |
US4431187A (en) * | 1982-06-25 | 1984-02-14 | Brunswick Corporation | Golf club shaft |
US4703008A (en) * | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
GB8404280D0 (en) * | 1984-02-17 | 1984-03-21 | Stanford J L | Biological preparations |
US4689397A (en) * | 1985-08-12 | 1987-08-25 | Scripps Clinic And Research Foundation | Synthetic polypeptides for detecting mycobacterial infections |
NL8701163A (nl) * | 1986-09-09 | 1988-04-05 | Nederlanden Staat | Gebruik van een peptide voor de bereiding van preparaten voor het verlichten, het behandelen en de diagnose van autoimmuunziekten, in het bijzonder arthritische toestanden, verbindingen die met dit peptide verwant zijn, alsmede farmaceutische en diagnostische preparaten en testkits. |
AU1548388A (en) * | 1987-02-02 | 1988-08-24 | Whitehead Institute For Biomedical Research | Mycobacterium tuberculosis genes and encoding protein antigens |
-
1987
- 1987-02-26 US US07/019,529 patent/US4952395A/en not_active Expired - Lifetime
-
1988
- 1988-02-24 NZ NZ223632A patent/NZ223632A/en unknown
- 1988-02-25 PT PT86838A patent/PT86838B/pt not_active IP Right Cessation
- 1988-02-25 CA CA000559844A patent/CA1340423C/en not_active Expired - Fee Related
- 1988-02-25 WO PCT/US1988/000598 patent/WO1988006591A1/en active IP Right Grant
- 1988-02-25 GR GR880100104A patent/GR1000083B/el not_active IP Right Cessation
- 1988-02-25 ZA ZA881344A patent/ZA881344B/xx unknown
- 1988-02-26 ES ES8800574A patent/ES2009238A6/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4952395A (en) | 1990-08-28 |
ZA881344B (en) | 1988-08-26 |
ES2009238A6 (es) | 1989-09-16 |
WO1988006591A1 (en) | 1988-09-07 |
CA1340423C (en) | 1999-03-09 |
PT86838A (pt) | 1988-03-01 |
PT86838B (pt) | 1992-05-29 |
NZ223632A (en) | 1991-03-26 |
GR880100104A (en) | 1988-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Right expired |