GEP20125595B - Milnacipran for long-term treatment of fibromyalgia syndrome - Google Patents
Milnacipran for long-term treatment of fibromyalgia syndromeInfo
- Publication number
- GEP20125595B GEP20125595B GEAP200610664A GEAP2006010664A GEP20125595B GE P20125595 B GEP20125595 B GE P20125595B GE AP200610664 A GEAP200610664 A GE AP200610664A GE AP2006010664 A GEAP2006010664 A GE AP2006010664A GE P20125595 B GEP20125595 B GE P20125595B
- Authority
- GE
- Georgia
- Prior art keywords
- milnacipran
- long
- term treatment
- fibromyalgia syndrome
- fibromyalgia
- Prior art date
Links
- 208000001640 Fibromyalgia Diseases 0.000 title abstract 3
- GJJFMKBJSRMPLA-HIFRSBDPSA-N (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide Chemical compound C=1C=CC=CC=1[C@@]1(C(=O)N(CC)CC)C[C@@H]1CN GJJFMKBJSRMPLA-HIFRSBDPSA-N 0.000 title abstract 2
- 229960000600 milnacipran Drugs 0.000 title abstract 2
- 238000011866 long-term treatment Methods 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72172205P | 2005-09-28 | 2005-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GEP20125595B true GEP20125595B (en) | 2012-08-10 |
Family
ID=37900431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GEAP200610664A GEP20125595B (en) | 2005-09-28 | 2006-09-27 | Milnacipran for long-term treatment of fibromyalgia syndrome |
Country Status (24)
Country | Link |
---|---|
US (1) | US7994220B2 (pt-PT) |
EP (2) | EP1928446A4 (pt-PT) |
JP (3) | JP2009510080A (pt-PT) |
KR (1) | KR20080055967A (pt-PT) |
CN (1) | CN101355930A (pt-PT) |
AU (1) | AU2006294645B2 (pt-PT) |
BR (1) | BRPI0617541A2 (pt-PT) |
CA (1) | CA2624018A1 (pt-PT) |
CR (1) | CR9882A (pt-PT) |
EC (1) | ECSP088407A (pt-PT) |
GE (1) | GEP20125595B (pt-PT) |
IL (2) | IL190284A (pt-PT) |
MA (1) | MA31720B1 (pt-PT) |
MY (1) | MY145340A (pt-PT) |
NI (1) | NI200800099A (pt-PT) |
NO (1) | NO20081951L (pt-PT) |
NZ (2) | NZ567271A (pt-PT) |
RU (1) | RU2437661C2 (pt-PT) |
SG (3) | SG10201807899PA (pt-PT) |
SV (1) | SV2008002855A (pt-PT) |
TN (1) | TNSN08129A1 (pt-PT) |
UA (1) | UA94721C2 (pt-PT) |
WO (1) | WO2007038620A2 (pt-PT) |
ZA (1) | ZA200803469B (pt-PT) |
Families Citing this family (20)
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US6602911B2 (en) * | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
WO2003077897A1 (en) * | 2002-03-15 | 2003-09-25 | Cypress Bioscience, Inc. | Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes |
JP2006504795A (ja) * | 2002-10-03 | 2006-02-09 | サイプレス バイオサイエンス, インコーポレイテッド | 神経学的障害を処置するための抗うつ剤の投薬量の段階的な漸増ならびに毎日の分割した投薬 |
US7994220B2 (en) * | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
TW200911225A (en) * | 2007-05-22 | 2009-03-16 | Cypress Bioscience Inc | Methods for improving physical function in fibromyalgia |
WO2009025091A1 (ja) * | 2007-08-23 | 2009-02-26 | St. Marianna University School Of Medicine | 線維筋痛症治療用医薬組成物 |
JP5274071B2 (ja) * | 2008-03-28 | 2013-08-28 | 旭化成ファーマ株式会社 | 線維筋痛症治療剤 |
CA2740029C (en) * | 2008-05-16 | 2016-12-20 | Axis, Inc. | Pharmaceutical composition for treatment of fibromyalgia |
EP2344447B1 (en) | 2008-10-08 | 2016-06-08 | Xgene Pharmaceutical Inc | Gaba conjugates and methods of use thereof |
US20100197797A1 (en) * | 2009-02-05 | 2010-08-05 | Rao Srinivas G | Methods of managing fibromyalgia using milnacipran |
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WO2010129689A1 (en) * | 2009-05-05 | 2010-11-11 | Forest Laboratories Holdings Limited | Milnacipran formulations |
LT2501234T (lt) | 2009-11-20 | 2017-12-11 | Tonix Pharma Holdings Limited | Būdai ir kompozicijos, skirti simptomų, susijusių su potrauminiu streso sutrikimu, gydymui naudojant ciklobenzapriną |
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US11998516B2 (en) * | 2011-03-07 | 2024-06-04 | Tonix Pharma Holdings Limited | Methods and compositions for treating depression using cyclobenzaprine |
FR2978350B1 (fr) | 2011-07-28 | 2013-11-08 | Pf Medicament | Medicament a base de levomilnacipran pour la rehabilitation fonctionnelle apres accident neurologique aigu |
KR101991980B1 (ko) * | 2011-09-06 | 2019-06-21 | 큐알엔에이, 인크. | 소형 분자로 전압-개폐된 나트륨 채널 (SCNxA)의 알파 아단위에 관련된 질환의 치료 |
HRP20240648T1 (hr) | 2013-03-15 | 2024-08-02 | Tonix Pharma Holdings Limited | Eutektičke formulacije ciklobenzaprin hidroklorida i manitola |
CA2961822A1 (en) | 2014-09-18 | 2016-03-24 | Tonix Pharma Holdings Limited | Eutectic formulations of cyclobenzaprine hydrochloride |
CN118267382A (zh) | 2017-12-11 | 2024-07-02 | 通尼克斯制药控股有限公司 | 用于痴呆和神经变性病况中的激越、精神病和认知衰退的环苯扎林治疗 |
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- 2006-09-26 US US11/535,237 patent/US7994220B2/en active Active
- 2006-09-27 CA CA002624018A patent/CA2624018A1/en not_active Abandoned
- 2006-09-27 RU RU2008112192/15A patent/RU2437661C2/ru active
- 2006-09-27 CN CNA200680036203XA patent/CN101355930A/zh active Pending
- 2006-09-27 EP EP06804211A patent/EP1928446A4/en not_active Withdrawn
- 2006-09-27 SG SG10201807899PA patent/SG10201807899PA/en unknown
- 2006-09-27 KR KR1020087010241A patent/KR20080055967A/ko not_active Application Discontinuation
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- 2006-09-27 WO PCT/US2006/037714 patent/WO2007038620A2/en active Application Filing
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