GB999237A - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- GB999237A GB999237A GB2488763A GB2488763A GB999237A GB 999237 A GB999237 A GB 999237A GB 2488763 A GB2488763 A GB 2488763A GB 2488763 A GB2488763 A GB 2488763A GB 999237 A GB999237 A GB 999237A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- formula
- compounds
- compound
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- QNGUPQRODVPRDC-UHFFFAOYSA-N 7-chloroquinoline Chemical compound C1=CC=NC2=CC(Cl)=CC=C21 QNGUPQRODVPRDC-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 238000009833 condensation Methods 0.000 abstract 2
- 230000005494 condensation Effects 0.000 abstract 2
- 125000003916 ethylene diamine group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OVVDHASRRHVOPG-UHFFFAOYSA-N 2-[2-[2-(1,3-dioxoisoindol-2-yl)ethyl-ethylamino]ethyl]isoindole-1,3-dione Chemical compound C(C)N(CCN1C(C=2C(C1=O)=CC=CC=2)=O)CCN1C(C=2C(C1=O)=CC=CC=2)=O OVVDHASRRHVOPG-UHFFFAOYSA-N 0.000 abstract 1
- RXFCIXRFAJRBSG-UHFFFAOYSA-N 3,2,3-tetramine Chemical compound NCCCNCCNCCCN RXFCIXRFAJRBSG-UHFFFAOYSA-N 0.000 abstract 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 230000000078 anti-malarial effect Effects 0.000 abstract 1
- 239000003430 antimalarial agent Substances 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 238000010531 catalytic reduction reaction Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- LQAWSZYJRFRCHK-UHFFFAOYSA-N n'-(2-aminoethyl)-n'-ethylethane-1,2-diamine Chemical compound NCCN(CC)CCN LQAWSZYJRFRCHK-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- FYRHIOVKTDQVFC-UHFFFAOYSA-M potassium phthalimide Chemical compound [K+].C1=CC=C2C(=O)[N-]C(=O)C2=C1 FYRHIOVKTDQVFC-UHFFFAOYSA-M 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR901653 | 1962-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB999237A true GB999237A (en) | 1965-07-21 |
Family
ID=8781651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2488763A Expired GB999237A (en) | 1962-06-22 | 1963-06-21 | Quinoline derivatives |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT240364B (enrdf_load_stackoverflow) |
| CH (1) | CH424781A (enrdf_load_stackoverflow) |
| DE (1) | DE1296635B (enrdf_load_stackoverflow) |
| DK (2) | DK107807C (enrdf_load_stackoverflow) |
| ES (1) | ES289291A1 (enrdf_load_stackoverflow) |
| GB (1) | GB999237A (enrdf_load_stackoverflow) |
| LU (1) | LU43783A1 (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001044198A1 (de) * | 1999-12-17 | 2001-06-21 | G.O.T. Gesellschaft Für Therapieoptimierung Und Targeting Entwicklungs Mbh | Amphiphile chinolylpolyamine als transfermittel für biologisch aktive makromoleküle |
| WO2007097450A1 (ja) * | 2006-02-27 | 2007-08-30 | Nagoya City University | 抗マラリア活性化合物、及びそれを有効成分とする抗マラリア薬 |
| JP2014513101A (ja) * | 2011-04-29 | 2014-05-29 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 新規のビスアミノキノリン化合物、それから調製した医薬組成物、及びそれらの使用 |
| US10221140B2 (en) | 2014-08-08 | 2019-03-05 | The Trustees Of The University Of Pennsylvania | Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1052356A (fr) * | 1952-03-12 | 1954-01-25 | Rhone Poulenc Sa | Nouveaux dérivés de la quinoléïne et leur procédé de préparation |
-
1963
- 1963-05-21 LU LU43783D patent/LU43783A1/xx unknown
- 1963-06-14 CH CH742463A patent/CH424781A/fr unknown
- 1963-06-18 DE DE1963R0035446 patent/DE1296635B/de active Pending
- 1963-06-21 AT AT500663A patent/AT240364B/de active
- 1963-06-21 GB GB2488763A patent/GB999237A/en not_active Expired
- 1963-06-22 DK DK288564A patent/DK107807C/da active
- 1963-06-22 ES ES289291A patent/ES289291A1/es not_active Expired
- 1963-06-22 DK DK297463A patent/DK104735C/da active
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001044198A1 (de) * | 1999-12-17 | 2001-06-21 | G.O.T. Gesellschaft Für Therapieoptimierung Und Targeting Entwicklungs Mbh | Amphiphile chinolylpolyamine als transfermittel für biologisch aktive makromoleküle |
| WO2007097450A1 (ja) * | 2006-02-27 | 2007-08-30 | Nagoya City University | 抗マラリア活性化合物、及びそれを有効成分とする抗マラリア薬 |
| JP2014513101A (ja) * | 2011-04-29 | 2014-05-29 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 新規のビスアミノキノリン化合物、それから調製した医薬組成物、及びそれらの使用 |
| AU2012249646B2 (en) * | 2011-04-29 | 2017-06-08 | The Trustees Of The University Of Pennsylvania | Novel bisaminoquinoline compounds, pharmaceutical compositions prepared therefrom and their use |
| US10047052B2 (en) | 2011-04-29 | 2018-08-14 | The Trustees Of The University Of Pennsylvania | Bisaminoquinoline compounds, pharmaceutical compositions prepared therefrom and their use |
| US11591298B2 (en) | 2011-04-29 | 2023-02-28 | The Trustees Of The University Of Pennsylvania | Bisaminoquinoline compounds, pharmaceutical compositions prepared therefrom and their use |
| US10221140B2 (en) | 2014-08-08 | 2019-03-05 | The Trustees Of The University Of Pennsylvania | Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy |
| US11001558B2 (en) | 2014-08-08 | 2021-05-11 | The Trustees Of The University Of Pennsylvania | Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy |
| US11639335B2 (en) | 2014-08-08 | 2023-05-02 | The Trustees Of The University Of Pennsylvania | Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy |
Also Published As
| Publication number | Publication date |
|---|---|
| LU43783A1 (enrdf_load_stackoverflow) | 1963-07-22 |
| DK107807C (da) | 1967-07-10 |
| AT240364B (de) | 1965-05-25 |
| ES289291A1 (es) | 1963-12-16 |
| DK104735C (da) | 1966-06-27 |
| CH424781A (fr) | 1966-11-30 |
| DE1296635B (de) | 1969-09-18 |
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