GB9920910D0 - Novel chalcones - Google Patents
Novel chalconesInfo
- Publication number
- GB9920910D0 GB9920910D0 GBGB9920910.8A GB9920910A GB9920910D0 GB 9920910 D0 GB9920910 D0 GB 9920910D0 GB 9920910 A GB9920910 A GB 9920910A GB 9920910 D0 GB9920910 D0 GB 9920910D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- medicament
- prevention
- manufacture
- useful
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- DQFBYFPFKXHELB-UHFFFAOYSA-N Chalcone Natural products C=1C=CC=CC=1C(=O)C=CC1=CC=CC=C1 DQFBYFPFKXHELB-UHFFFAOYSA-N 0.000 title 1
- 150000001789 chalcones Chemical class 0.000 title 1
- 235000005513 chalcones Nutrition 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 208000017657 Menopausal disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 150000001788 chalcone derivatives Chemical class 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9920910.8A GB9920910D0 (en) | 1999-09-03 | 1999-09-03 | Novel chalcones |
| JP2001522211A JP2003508527A (ja) | 1999-09-03 | 2000-08-28 | 新規カルコン類 |
| CA002382130A CA2382130A1 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| HK02105661.5A HK1043999B (en) | 1999-09-03 | 2000-08-28 | New chalcone |
| SK311-2002A SK3112002A3 (en) | 1999-09-03 | 2000-08-28 | Derivatives of chalcones, pharmaceutical composition comprising them and their use |
| CZ2002787A CZ2002787A3 (cs) | 1999-09-03 | 2000-08-28 | Nové chalkony |
| HU0202579A HUP0202579A3 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| AU75109/00A AU776226B2 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| DK00964042T DK1212315T3 (da) | 1999-09-03 | 2000-08-28 | Nye chalconer |
| CNB008123039A CN1177843C (zh) | 1999-09-03 | 2000-08-28 | 新的查耳酮 |
| DE60001851T DE60001851T2 (de) | 1999-09-03 | 2000-08-28 | Neue chalchone |
| SI200030110T SI1212315T1 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| PL00353064A PL353064A1 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| EP00964042A EP1212315B1 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| ES00964042T ES2193106T3 (es) | 1999-09-03 | 2000-08-28 | Nuevas chalconas. |
| AT00964042T ATE235483T1 (de) | 1999-09-03 | 2000-08-28 | Neue chalchone |
| RU2002108566/04A RU2252938C2 (ru) | 1999-09-03 | 2000-08-28 | Халконы и фармацевтическая композиция на их основе |
| PCT/EP2000/008366 WO2001017988A1 (en) | 1999-09-03 | 2000-08-28 | Novel chalcones |
| PT00964042T PT1212315E (pt) | 1999-09-03 | 2000-08-28 | Novas calconas |
| KR1020027002798A KR100819576B1 (ko) | 1999-09-03 | 2000-08-28 | 신규 찰콘 화합물 |
| US10/075,626 US6620842B2 (en) | 1999-09-03 | 2002-02-15 | Chalcones |
| NO20021049A NO20021049L (no) | 1999-09-03 | 2002-03-01 | Nye chalkoner |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9920910.8A GB9920910D0 (en) | 1999-09-03 | 1999-09-03 | Novel chalcones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9920910D0 true GB9920910D0 (en) | 1999-11-10 |
Family
ID=10860346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9920910.8A Ceased GB9920910D0 (en) | 1999-09-03 | 1999-09-03 | Novel chalcones |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6620842B2 (https=) |
| EP (1) | EP1212315B1 (https=) |
| JP (1) | JP2003508527A (https=) |
| KR (1) | KR100819576B1 (https=) |
| CN (1) | CN1177843C (https=) |
| AT (1) | ATE235483T1 (https=) |
| AU (1) | AU776226B2 (https=) |
| CA (1) | CA2382130A1 (https=) |
| CZ (1) | CZ2002787A3 (https=) |
| DE (1) | DE60001851T2 (https=) |
| DK (1) | DK1212315T3 (https=) |
| ES (1) | ES2193106T3 (https=) |
| GB (1) | GB9920910D0 (https=) |
| HK (1) | HK1043999B (https=) |
| HU (1) | HUP0202579A3 (https=) |
| NO (1) | NO20021049L (https=) |
| PL (1) | PL353064A1 (https=) |
| PT (1) | PT1212315E (https=) |
| RU (1) | RU2252938C2 (https=) |
| SK (1) | SK3112002A3 (https=) |
| WO (1) | WO2001017988A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ536190A (en) | 2002-04-17 | 2007-08-31 | Cytokinetics Inc | Compounds for treating cellular proliferative diseases by modulating the activity of the mitotic kinesin KSP |
| US7638554B2 (en) * | 2002-04-18 | 2009-12-29 | Sri International | Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
| US20030229136A1 (en) * | 2002-04-18 | 2003-12-11 | Nurulain Zaveri | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents |
| DE60326248D1 (de) | 2002-07-17 | 2009-04-02 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen |
| US6864264B1 (en) * | 2002-08-20 | 2005-03-08 | Gloria L. Anderson | 1-adamantyl chalcones for the treatment of proliferative disorders |
| CN100336797C (zh) * | 2005-08-19 | 2007-09-12 | 浙江大学 | 四取代查耳酮衍生物及制备方法和用途 |
| WO2013127361A1 (en) * | 2012-03-01 | 2013-09-06 | The Hong Kong Polytechnic University | Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU634994B2 (en) * | 1988-12-21 | 1993-03-11 | Pharmacia & Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
| US5023341A (en) * | 1989-09-19 | 1991-06-11 | Allergan, Inc. | Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity |
| US4996230A (en) * | 1990-02-16 | 1991-02-26 | Eli Lilly And Company | Leukotriene antagonists |
| CA2084208A1 (en) * | 1990-05-17 | 1991-11-18 | Barry Markaverich | Growth inhibitors and methods of treating cancer and cell proliferative diseases |
| IT1271301B (it) | 1994-12-20 | 1997-05-27 | Indena Spa | Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono |
| US5525625A (en) * | 1995-01-24 | 1996-06-11 | Warner-Lambert Company | 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders |
-
1999
- 1999-09-03 GB GBGB9920910.8A patent/GB9920910D0/en not_active Ceased
-
2000
- 2000-08-28 AT AT00964042T patent/ATE235483T1/de not_active IP Right Cessation
- 2000-08-28 PT PT00964042T patent/PT1212315E/pt unknown
- 2000-08-28 RU RU2002108566/04A patent/RU2252938C2/ru not_active IP Right Cessation
- 2000-08-28 JP JP2001522211A patent/JP2003508527A/ja not_active Withdrawn
- 2000-08-28 CN CNB008123039A patent/CN1177843C/zh not_active Expired - Fee Related
- 2000-08-28 PL PL00353064A patent/PL353064A1/xx not_active IP Right Cessation
- 2000-08-28 EP EP00964042A patent/EP1212315B1/en not_active Expired - Lifetime
- 2000-08-28 CZ CZ2002787A patent/CZ2002787A3/cs unknown
- 2000-08-28 SK SK311-2002A patent/SK3112002A3/sk unknown
- 2000-08-28 ES ES00964042T patent/ES2193106T3/es not_active Expired - Lifetime
- 2000-08-28 WO PCT/EP2000/008366 patent/WO2001017988A1/en not_active Ceased
- 2000-08-28 HK HK02105661.5A patent/HK1043999B/en unknown
- 2000-08-28 DK DK00964042T patent/DK1212315T3/da active
- 2000-08-28 AU AU75109/00A patent/AU776226B2/en not_active Ceased
- 2000-08-28 KR KR1020027002798A patent/KR100819576B1/ko not_active Expired - Fee Related
- 2000-08-28 CA CA002382130A patent/CA2382130A1/en not_active Abandoned
- 2000-08-28 DE DE60001851T patent/DE60001851T2/de not_active Expired - Fee Related
- 2000-08-28 HU HU0202579A patent/HUP0202579A3/hu unknown
-
2002
- 2002-02-15 US US10/075,626 patent/US6620842B2/en not_active Expired - Fee Related
- 2002-03-01 NO NO20021049A patent/NO20021049L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2382130A1 (en) | 2001-03-15 |
| CN1371372A (zh) | 2002-09-25 |
| HUP0202579A2 (hu) | 2002-11-28 |
| SK3112002A3 (en) | 2003-10-07 |
| PT1212315E (pt) | 2003-08-29 |
| DE60001851D1 (de) | 2003-04-30 |
| CZ2002787A3 (cs) | 2002-06-12 |
| WO2001017988A1 (en) | 2001-03-15 |
| NO20021049L (no) | 2002-05-03 |
| AU776226B2 (en) | 2004-09-02 |
| KR100819576B1 (ko) | 2008-04-22 |
| HK1043999B (en) | 2003-08-15 |
| ES2193106T3 (es) | 2003-11-01 |
| EP1212315B1 (en) | 2003-03-26 |
| EP1212315A1 (en) | 2002-06-12 |
| US6620842B2 (en) | 2003-09-16 |
| AU7510900A (en) | 2001-04-10 |
| US20030055056A1 (en) | 2003-03-20 |
| HK1043999A1 (en) | 2002-10-04 |
| HUP0202579A3 (en) | 2003-07-28 |
| KR20020031598A (ko) | 2002-05-02 |
| DE60001851T2 (de) | 2003-12-11 |
| PL353064A1 (en) | 2003-10-06 |
| JP2003508527A (ja) | 2003-03-04 |
| RU2252938C2 (ru) | 2005-05-27 |
| ATE235483T1 (de) | 2003-04-15 |
| CN1177843C (zh) | 2004-12-01 |
| NO20021049D0 (no) | 2002-03-01 |
| DK1212315T3 (da) | 2003-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |