DK1212315T3 - Nye chalconer - Google Patents

Nye chalconer

Info

Publication number
DK1212315T3
DK1212315T3 DK00964042T DK00964042T DK1212315T3 DK 1212315 T3 DK1212315 T3 DK 1212315T3 DK 00964042 T DK00964042 T DK 00964042T DK 00964042 T DK00964042 T DK 00964042T DK 1212315 T3 DK1212315 T3 DK 1212315T3
Authority
DK
Denmark
Prior art keywords
chalconer
new
medicament
prevention
manufacture
Prior art date
Application number
DK00964042T
Other languages
Danish (da)
English (en)
Inventor
Ezio Bombardelli
Piero Valenti
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1212315T3 publication Critical patent/DK1212315T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • C07D311/84Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK00964042T 1999-09-03 2000-08-28 Nye chalconer DK1212315T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9920910.8A GB9920910D0 (en) 1999-09-03 1999-09-03 Novel chalcones
PCT/EP2000/008366 WO2001017988A1 (en) 1999-09-03 2000-08-28 Novel chalcones

Publications (1)

Publication Number Publication Date
DK1212315T3 true DK1212315T3 (da) 2003-06-23

Family

ID=10860346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00964042T DK1212315T3 (da) 1999-09-03 2000-08-28 Nye chalconer

Country Status (21)

Country Link
US (1) US6620842B2 (https=)
EP (1) EP1212315B1 (https=)
JP (1) JP2003508527A (https=)
KR (1) KR100819576B1 (https=)
CN (1) CN1177843C (https=)
AT (1) ATE235483T1 (https=)
AU (1) AU776226B2 (https=)
CA (1) CA2382130A1 (https=)
CZ (1) CZ2002787A3 (https=)
DE (1) DE60001851T2 (https=)
DK (1) DK1212315T3 (https=)
ES (1) ES2193106T3 (https=)
GB (1) GB9920910D0 (https=)
HK (1) HK1043999B (https=)
HU (1) HUP0202579A3 (https=)
NO (1) NO20021049L (https=)
PL (1) PL353064A1 (https=)
PT (1) PT1212315E (https=)
RU (1) RU2252938C2 (https=)
SK (1) SK3112002A3 (https=)
WO (1) WO2001017988A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ536190A (en) 2002-04-17 2007-08-31 Cytokinetics Inc Compounds for treating cellular proliferative diseases by modulating the activity of the mitotic kinesin KSP
US7638554B2 (en) * 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US20030229136A1 (en) * 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
DE60326248D1 (de) 2002-07-17 2009-04-02 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen
US6864264B1 (en) * 2002-08-20 2005-03-08 Gloria L. Anderson 1-adamantyl chalcones for the treatment of proliferative disorders
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
WO2013127361A1 (en) * 2012-03-01 2013-09-06 The Hong Kong Polytechnic University Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634994B2 (en) * 1988-12-21 1993-03-11 Pharmacia & Upjohn Company Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
CA2084208A1 (en) * 1990-05-17 1991-11-18 Barry Markaverich Growth inhibitors and methods of treating cancer and cell proliferative diseases
IT1271301B (it) 1994-12-20 1997-05-27 Indena Spa Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
US5525625A (en) * 1995-01-24 1996-06-11 Warner-Lambert Company 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders

Also Published As

Publication number Publication date
CA2382130A1 (en) 2001-03-15
CN1371372A (zh) 2002-09-25
HUP0202579A2 (hu) 2002-11-28
SK3112002A3 (en) 2003-10-07
PT1212315E (pt) 2003-08-29
DE60001851D1 (de) 2003-04-30
CZ2002787A3 (cs) 2002-06-12
WO2001017988A1 (en) 2001-03-15
NO20021049L (no) 2002-05-03
AU776226B2 (en) 2004-09-02
KR100819576B1 (ko) 2008-04-22
HK1043999B (en) 2003-08-15
ES2193106T3 (es) 2003-11-01
EP1212315B1 (en) 2003-03-26
EP1212315A1 (en) 2002-06-12
US6620842B2 (en) 2003-09-16
AU7510900A (en) 2001-04-10
GB9920910D0 (en) 1999-11-10
US20030055056A1 (en) 2003-03-20
HK1043999A1 (en) 2002-10-04
HUP0202579A3 (en) 2003-07-28
KR20020031598A (ko) 2002-05-02
DE60001851T2 (de) 2003-12-11
PL353064A1 (en) 2003-10-06
JP2003508527A (ja) 2003-03-04
RU2252938C2 (ru) 2005-05-27
ATE235483T1 (de) 2003-04-15
CN1177843C (zh) 2004-12-01
NO20021049D0 (no) 2002-03-01

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