GB991140A - Manufacture of naphthalene derivatives - Google Patents

Manufacture of naphthalene derivatives

Info

Publication number
GB991140A
GB991140A GB1984562A GB1984562A GB991140A GB 991140 A GB991140 A GB 991140A GB 1984562 A GB1984562 A GB 1984562A GB 1984562 A GB1984562 A GB 1984562A GB 991140 A GB991140 A GB 991140A
Authority
GB
United Kingdom
Prior art keywords
stands
radical
acid addition
formula
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1984562A
Inventor
Ralph Howe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB1984562A priority Critical patent/GB991140A/en
Publication of GB991140A publication Critical patent/GB991140A/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the general formula <FORM:0991140/C2/1> (wherein R1 stands for a hydrogen atom or a methyl radical and R2 stands for a branched chain propyl or butyl radical) and non-toxic, pharmaceutically-acceptable acid addition salts thereof are prepared by (a) reducing an aminoacetylnaphthalene derivative of the formula <FORM:0991140/C2/2> or an acid addition salt thereof with lithium aluminium hydride; or (b)-in the case of compounds wherein R1 stands for a hydrogen atom and R2 stands for an isopropyl, isobutyl or S-butyl radical-interacting an amino compound of the formula <FORM:0991140/C2/3> (wherein A stands for the radical CO or CHOH) or an acid addition salt thereof with a carbonyl compound of the formula R3COR4 (wherein R3 stands for a hydrogen atom and R4 stands for an isopropyl radical, or R3 stands for a methyl radical and R4 stands for a methyl or ethyl radical) and an alkali metal borohydride, optionally followed in either case by acid addition salt formation. The starting materials for process (a) may be prepared from a 2-naphthacyl halide and the appropriate amine.
GB1984562A 1962-05-23 1962-05-23 Manufacture of naphthalene derivatives Expired GB991140A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1984562A GB991140A (en) 1962-05-23 1962-05-23 Manufacture of naphthalene derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1984562A GB991140A (en) 1962-05-23 1962-05-23 Manufacture of naphthalene derivatives

Publications (1)

Publication Number Publication Date
GB991140A true GB991140A (en) 1965-05-05

Family

ID=10136176

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1984562A Expired GB991140A (en) 1962-05-23 1962-05-23 Manufacture of naphthalene derivatives

Country Status (1)

Country Link
GB (1) GB991140A (en)

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