GB991140A - Manufacture of naphthalene derivatives - Google Patents
Manufacture of naphthalene derivativesInfo
- Publication number
- GB991140A GB991140A GB1984562A GB1984562A GB991140A GB 991140 A GB991140 A GB 991140A GB 1984562 A GB1984562 A GB 1984562A GB 1984562 A GB1984562 A GB 1984562A GB 991140 A GB991140 A GB 991140A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stands
- radical
- acid addition
- formula
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compounds of the general formula <FORM:0991140/C2/1> (wherein R1 stands for a hydrogen atom or a methyl radical and R2 stands for a branched chain propyl or butyl radical) and non-toxic, pharmaceutically-acceptable acid addition salts thereof are prepared by (a) reducing an aminoacetylnaphthalene derivative of the formula <FORM:0991140/C2/2> or an acid addition salt thereof with lithium aluminium hydride; or (b)-in the case of compounds wherein R1 stands for a hydrogen atom and R2 stands for an isopropyl, isobutyl or S-butyl radical-interacting an amino compound of the formula <FORM:0991140/C2/3> (wherein A stands for the radical CO or CHOH) or an acid addition salt thereof with a carbonyl compound of the formula R3COR4 (wherein R3 stands for a hydrogen atom and R4 stands for an isopropyl radical, or R3 stands for a methyl radical and R4 stands for a methyl or ethyl radical) and an alkali metal borohydride, optionally followed in either case by acid addition salt formation. The starting materials for process (a) may be prepared from a 2-naphthacyl halide and the appropriate amine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1984562A GB991140A (en) | 1962-05-23 | 1962-05-23 | Manufacture of naphthalene derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1984562A GB991140A (en) | 1962-05-23 | 1962-05-23 | Manufacture of naphthalene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB991140A true GB991140A (en) | 1965-05-05 |
Family
ID=10136176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1984562A Expired GB991140A (en) | 1962-05-23 | 1962-05-23 | Manufacture of naphthalene derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB991140A (en) |
-
1962
- 1962-05-23 GB GB1984562A patent/GB991140A/en not_active Expired
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