GB990860A - N,n-disubstituted sulfamylureas and compositions thereof - Google Patents
N,n-disubstituted sulfamylureas and compositions thereofInfo
- Publication number
- GB990860A GB990860A GB484762A GB484762A GB990860A GB 990860 A GB990860 A GB 990860A GB 484762 A GB484762 A GB 484762A GB 484762 A GB484762 A GB 484762A GB 990860 A GB990860 A GB 990860A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- group
- appropriate
- thiamorpholino
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 13
- -1 piperazino Chemical group 0.000 abstract 9
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical class NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- XKAFKUGMXFMRCC-UHFFFAOYSA-N 1,1-diphenylurea Chemical class C=1C=CC=CC=1N(C(=O)N)C1=CC=CC=C1 XKAFKUGMXFMRCC-UHFFFAOYSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 125000004803 chlorobenzyl group Chemical group 0.000 abstract 1
- 235000009508 confectionery Nutrition 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 229940126904 hypoglycaemic agent Drugs 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 239000007937 lozenge Substances 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 125000001326 naphthylalkyl group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB484762A GB990860A (en) | 1962-02-08 | 1962-02-08 | N,n-disubstituted sulfamylureas and compositions thereof |
| BE660736A BE660736A (enExample) | 1962-02-08 | 1965-03-05 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB484762A GB990860A (en) | 1962-02-08 | 1962-02-08 | N,n-disubstituted sulfamylureas and compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB990860A true GB990860A (en) | 1965-05-05 |
Family
ID=9784917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB484762A Expired GB990860A (en) | 1962-02-08 | 1962-02-08 | N,n-disubstituted sulfamylureas and compositions thereof |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE660736A (enExample) |
| GB (1) | GB990860A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992008694A1 (en) * | 1990-11-07 | 1992-05-29 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
-
1962
- 1962-02-08 GB GB484762A patent/GB990860A/en not_active Expired
-
1965
- 1965-03-05 BE BE660736A patent/BE660736A/xx unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992008694A1 (en) * | 1990-11-07 | 1992-05-29 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| US5214206A (en) * | 1990-11-07 | 1993-05-25 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| US5288757A (en) * | 1990-11-07 | 1994-02-22 | Warner-Lambert Company | Aminosulfonyl urea ACAT inhibitors and a method of lowering blood cholesterol levels therewith |
Also Published As
| Publication number | Publication date |
|---|---|
| BE660736A (enExample) | 1965-07-01 |
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