GB985634A - Novel steroid esters, their preparation and employment - Google Patents
Novel steroid esters, their preparation and employmentInfo
- Publication number
- GB985634A GB985634A GB31436/63A GB3143663A GB985634A GB 985634 A GB985634 A GB 985634A GB 31436/63 A GB31436/63 A GB 31436/63A GB 3143663 A GB3143663 A GB 3143663A GB 985634 A GB985634 A GB 985634A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hexahydrobenzyloxycarbonyloxy
- preparation
- estra
- triene
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 steroid esters Chemical class 0.000 title abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- CZMFJPMSMGCQGL-VMBLQBCYSA-N [(8R,9S,13S,14S,17S)-17-(cyclohexylmethoxycarbonyloxy)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate Chemical compound C(C)(=O)OC1=CC=2CC[C@H]3[C@@H]4CC[C@@H]([C@@]4(C)CC[C@@H]3C2C=C1)OC(=O)OCC1CCCCC1 CZMFJPMSMGCQGL-VMBLQBCYSA-N 0.000 abstract 1
- RIRJSPYWCQLBKX-JJAANBCZSA-N cyclohexylmethyl [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] carbonate Chemical compound C(C1CCCCC1)OC(=O)O[C@@H]1CC2=CC[C@H]3[C@@H]4CCC([C@@]4(C)CC[C@@H]3[C@]2(CC1)C)=O RIRJSPYWCQLBKX-JJAANBCZSA-N 0.000 abstract 1
- AOQONNCNKUWWRI-UHFFFAOYSA-N cyclohexylmethyl carbonochloridate Chemical compound ClC(=O)OCC1CCCCC1 AOQONNCNKUWWRI-UHFFFAOYSA-N 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 239000007927 intramuscular injection Substances 0.000 abstract 1
- 238000010255 intramuscular injection Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007929 subcutaneous injection Substances 0.000 abstract 1
- 238000010254 subcutaneous injection Methods 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR907178A FR1421227A (fr) | 1962-08-17 | 1962-08-17 | Hexahydrobenzyl carbonates stéroïdes et procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB985634A true GB985634A (en) | 1965-03-10 |
Family
ID=8785329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31436/63A Expired GB985634A (en) | 1962-08-17 | 1963-08-08 | Novel steroid esters, their preparation and employment |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE636216A (enrdf_load_stackoverflow) |
| CA (1) | CA745995A (enrdf_load_stackoverflow) |
| CH (1) | CH405303A (enrdf_load_stackoverflow) |
| DE (1) | DE1300110B (enrdf_load_stackoverflow) |
| ES (1) | ES290864A1 (enrdf_load_stackoverflow) |
| FR (2) | FR1421227A (enrdf_load_stackoverflow) |
| GB (1) | GB985634A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531089A1 (fr) * | 1982-07-27 | 1984-02-03 | Pharmascience Lab | Nouveaux derives oestraniques destines a des applications pharmacologiques par voie topique, et leur procede de preparation |
| WO1995001988A1 (de) * | 1993-07-03 | 1995-01-19 | Jenapharm Gmbh | ORAL ESTROGEN WIRKSAME ESTER DES 14α,15α-METHYLEN-ESTRADIOLS |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6740646B2 (en) | 2002-01-16 | 2004-05-25 | Biotest Laboratories, Llc | Bioavailable prodrugs of androgenic steroids and related method |
| US6818668B2 (en) | 2002-04-12 | 2004-11-16 | Biotest Laboratories, Llc | 5-alkyl-7-alkylcarbonate-isoflavone ester and related method |
-
0
- CA CA745995A patent/CA745995A/en not_active Expired
-
1962
- 1962-08-17 FR FR907178A patent/FR1421227A/fr not_active Expired
- 1962-11-16 FR FR915659A patent/FR2444M/fr not_active Expired
-
1963
- 1963-08-05 CH CH965563A patent/CH405303A/fr unknown
- 1963-08-08 GB GB31436/63A patent/GB985634A/en not_active Expired
- 1963-08-12 DE DER35893A patent/DE1300110B/de active Pending
- 1963-08-14 BE BE636216A patent/BE636216A/fr unknown
- 1963-08-16 ES ES0290864A patent/ES290864A1/es not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531089A1 (fr) * | 1982-07-27 | 1984-02-03 | Pharmascience Lab | Nouveaux derives oestraniques destines a des applications pharmacologiques par voie topique, et leur procede de preparation |
| WO1995001988A1 (de) * | 1993-07-03 | 1995-01-19 | Jenapharm Gmbh | ORAL ESTROGEN WIRKSAME ESTER DES 14α,15α-METHYLEN-ESTRADIOLS |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1300110B (de) | 1969-07-31 |
| FR1421227A (fr) | 1965-12-17 |
| FR2444M (enrdf_load_stackoverflow) | 1964-05-08 |
| CA745995A (en) | 1966-11-08 |
| ES290864A1 (es) | 1963-11-16 |
| CH405303A (fr) | 1966-01-15 |
| BE636216A (fr) | 1964-02-14 |
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