GB982613A - New aminopyrazoles and process for preparing same - Google Patents
New aminopyrazoles and process for preparing sameInfo
- Publication number
- GB982613A GB982613A GB1435/63A GB143563A GB982613A GB 982613 A GB982613 A GB 982613A GB 1435/63 A GB1435/63 A GB 1435/63A GB 143563 A GB143563 A GB 143563A GB 982613 A GB982613 A GB 982613A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- pyridyl
- group
- compounds
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JVVRJMXHNUAPHW-UHFFFAOYSA-N 1h-pyrazol-5-amine Chemical class NC=1C=CNN=1 JVVRJMXHNUAPHW-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 150000003938 benzyl alcohols Chemical class 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- OAKJQQAXSVQMHS-UHFFFAOYSA-N hydrazine Substances NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- -1 monosubstituted acetonitrile Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH78762A CH440293A (de) | 1962-01-23 | 1962-01-23 | Verfahren zur Herstellung neuer Aminopyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB982613A true GB982613A (en) | 1965-02-10 |
Family
ID=4195173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1435/63A Expired GB982613A (en) | 1962-01-23 | 1963-01-11 | New aminopyrazoles and process for preparing same |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US3228947A (en:Method) |
| BE (2) | BE627394A (en:Method) |
| CH (1) | CH440293A (en:Method) |
| DE (2) | DE1445580A1 (en:Method) |
| GB (1) | GB982613A (en:Method) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1295560B (de) * | 1963-07-24 | 1969-05-22 | Heyden Chem Fab | Verfahren zur Herstellung von substituierten 5-Aminopyrazolen |
| US4347251A (en) * | 1981-07-13 | 1982-08-31 | American Cyanamid Company | Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines |
| AU2011238616B2 (en) | 2010-03-30 | 2016-08-04 | Verseon Corporation | Multisubstituted aromatic compounds as inhibitors of thrombin |
| EA026692B1 (ru) | 2010-06-30 | 2017-05-31 | Айронвуд Фармасьютикелз, Инк. | Стимуляторы sgc |
| ES2572803T3 (es) | 2010-11-09 | 2016-06-02 | Ironwood Pharmaceuticals, Inc. | Estimuladores de GCs |
| CA2861804C (en) | 2011-12-27 | 2021-10-26 | Ironwood Pharmaceuticals, Inc. | 2-benzyl,3(pyrimidin-2-yl)substituted pyrazoles useful as sgc stimulators |
| WO2014060381A1 (de) * | 2012-10-18 | 2014-04-24 | Bayer Cropscience Ag | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
| US9533970B2 (en) | 2013-03-15 | 2017-01-03 | Verseon Corporation | Multisubstituted aromatic compounds as serine protease inhibitors |
| CN110423221A (zh) | 2013-03-15 | 2019-11-08 | 维颂公司 | 作为凝血酶抑制剂的卤代吡唑 |
| BR112017004704A2 (pt) | 2014-09-17 | 2018-01-23 | Verseon Corp | composto, composição farmacêutica, e, método para tratar uma doença ou distúrbio em um indivíduo |
| PT3261639T (pt) | 2015-02-27 | 2022-11-25 | Verseon Int Corporation | Compostos de pirazol substituídos como inibidores de serina protéase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3014038A (en) * | 1961-12-19 | Xnhxs | ||
| US2833779A (en) * | 1956-10-29 | 1958-05-06 | American Cyanamid Co | Substituted pyrazoles |
| NL253320A (en:Method) * | 1959-07-03 | |||
| US3041343A (en) * | 1959-10-14 | 1962-06-26 | Sandoz Ltd | 4-(thienyl-2'')-and 4-(pyridyl-3'')-5-aminopyrazoles |
-
0
- BE BE627393D patent/BE627393A/xx unknown
- BE BE627394D patent/BE627394A/xx unknown
-
1962
- 1962-01-23 CH CH78762A patent/CH440293A/de unknown
- 1962-11-21 US US240198A patent/US3228947A/en not_active Expired - Lifetime
-
1963
- 1963-01-11 GB GB1435/63A patent/GB982613A/en not_active Expired
- 1963-01-15 US US251496A patent/US3250761A/en not_active Expired - Lifetime
- 1963-01-18 DE DE19631445580 patent/DE1445580A1/de active Pending
- 1963-01-18 DE DE19631545699 patent/DE1545699A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3228947A (en) | 1966-01-11 |
| BE627393A (en:Method) | |
| CH440293A (de) | 1967-07-31 |
| DE1445580A1 (de) | 1969-03-13 |
| US3250761A (en) | 1966-05-10 |
| BE627394A (en:Method) | |
| DE1545699A1 (de) | 1969-06-26 |
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