GB980777A - ª‡-amino-substituted penicillins - Google Patents
ª‡-amino-substituted penicillinsInfo
- Publication number
- GB980777A GB980777A GB44728/62A GB4472862A GB980777A GB 980777 A GB980777 A GB 980777A GB 44728/62 A GB44728/62 A GB 44728/62A GB 4472862 A GB4472862 A GB 4472862A GB 980777 A GB980777 A GB 980777A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- hydroxy
- sodium
- amino
- aldehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930182555 Penicillin Natural products 0.000 title abstract 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 6
- -1 N-protected amino-substituted carboxylic acid Chemical class 0.000 abstract 6
- 239000011734 sodium Substances 0.000 abstract 6
- 229910052708 sodium Inorganic materials 0.000 abstract 6
- NTCCNERMXRIPTR-UHFFFAOYSA-N 2-hydroxy-1-naphthaldehyde Chemical compound C1=CC=CC2=C(C=O)C(O)=CC=C21 NTCCNERMXRIPTR-UHFFFAOYSA-N 0.000 abstract 4
- SMQUZDBALVYZAC-UHFFFAOYSA-N salicylaldehyde Chemical compound OC1=CC=CC=C1C=O SMQUZDBALVYZAC-UHFFFAOYSA-N 0.000 abstract 4
- SNDPXSYFESPGGJ-UHFFFAOYSA-N 2-aminopentanoic acid Chemical compound CCCC(N)C(O)=O SNDPXSYFESPGGJ-UHFFFAOYSA-N 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 2
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 2
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- YZAIBLBSRBVPIU-UHFFFAOYSA-N 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]-4-methylsulfanylbutanoic acid Chemical compound OC1=C(C2=CC=CC=C2C=C1)C=NC(CCSC)C(=O)O YZAIBLBSRBVPIU-UHFFFAOYSA-N 0.000 abstract 1
- YEMXJBMTPUAREO-UHFFFAOYSA-N 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]pentanoic acid Chemical compound OC1=C(C2=CC=CC=C2C=C1)C=NC(CCC)C(=O)O YEMXJBMTPUAREO-UHFFFAOYSA-N 0.000 abstract 1
- DJCVELDWDCGLML-UHFFFAOYSA-N 2-[(3,5-dichloro-2-hydroxyphenyl)methylideneamino]pentanoic acid Chemical compound ClC1=C(C(C=NC(CCC)C(=O)O)=CC(=C1)Cl)O DJCVELDWDCGLML-UHFFFAOYSA-N 0.000 abstract 1
- FABVMBDCVAJXMB-UHFFFAOYSA-N 3,5-dichloro-2-hydroxybenzaldehyde Chemical compound OC1=C(Cl)C=C(Cl)C=C1C=O FABVMBDCVAJXMB-UHFFFAOYSA-N 0.000 abstract 1
- NVLPDIRQWJSXLZ-UHFFFAOYSA-N 3-hydroxypyridine-4-carbaldehyde Chemical compound OC1=CN=CC=C1C=O NVLPDIRQWJSXLZ-UHFFFAOYSA-N 0.000 abstract 1
- FUGKCSRLAQKUHG-UHFFFAOYSA-N 5-chloro-2-hydroxybenzaldehyde Chemical compound OC1=CC=C(Cl)C=C1C=O FUGKCSRLAQKUHG-UHFFFAOYSA-N 0.000 abstract 1
- WUDICNXHPWIORK-UHFFFAOYSA-N ClC1=C(C(C=O)=CC(=C1)Cl)O.ClC1=CC=C(C(C=O)=C1)O Chemical compound ClC1=C(C(C=O)=CC(=C1)Cl)O.ClC1=CC=C(C(C=O)=C1)O WUDICNXHPWIORK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004470 DL Methionine Substances 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical group N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- AOGYCOYQMAVAFD-UHFFFAOYSA-N chlorocarbonic acid Chemical compound OC(Cl)=O AOGYCOYQMAVAFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 235000006109 methionine Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL300841D NL300841A (enExample) | 1962-11-27 | ||
| GB44728/62A GB980777A (en) | 1962-11-27 | 1962-11-27 | ª‡-amino-substituted penicillins |
| BR154617/63A BR6354617D0 (pt) | 1962-11-27 | 1963-11-19 | Processo para a preparacao de penicilinas d-amino substituidas |
| FR954869A FR1393286A (fr) | 1962-11-27 | 1963-11-25 | Procédé de préparation de pénicillines |
| BE640432D BE640432A (enExample) | 1962-11-27 | 1963-11-26 | |
| US326249A US3230214A (en) | 1962-11-27 | 1963-11-26 | Preparation of 6-aminoacylpenicillanic acids |
| FI632313A FI42331C (fi) | 1962-11-27 | 1963-11-26 | Menetelmä alfa-amino-substituoitujen penisilliinien valmistamiseksi |
| AT945363A AT249860B (de) | 1962-11-27 | 1963-11-26 | Verfahren zur Herstellung von α-Aminoacyl-6-aminopenicillansäurederivaten |
| CH1447663A CH435289A (de) | 1962-11-27 | 1963-11-26 | Verfahren zur Herstellung von Penicillinen |
| ES0293930A ES293930A1 (es) | 1962-11-27 | 1963-11-27 | Un procedimiento para la preparaciën de penicilinas |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB44728/62A GB980777A (en) | 1962-11-27 | 1962-11-27 | ª‡-amino-substituted penicillins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB980777A true GB980777A (en) | 1965-01-20 |
Family
ID=10434500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44728/62A Expired GB980777A (en) | 1962-11-27 | 1962-11-27 | ª‡-amino-substituted penicillins |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3230214A (enExample) |
| AT (1) | AT249860B (enExample) |
| BE (1) | BE640432A (enExample) |
| BR (1) | BR6354617D0 (enExample) |
| CH (1) | CH435289A (enExample) |
| ES (1) | ES293930A1 (enExample) |
| FI (1) | FI42331C (enExample) |
| FR (1) | FR1393286A (enExample) |
| GB (1) | GB980777A (enExample) |
| NL (1) | NL300841A (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3304301A (en) * | 1962-12-27 | 1967-02-14 | Rit Rech Ind Therapeut | Derivatives of 6-aminopenicillanic acid |
| FR2014689A1 (en) * | 1968-07-23 | 1970-04-17 | Erasme | Enzymatic prepn of semi-synthetic penicillins |
| US3886140A (en) * | 1972-05-30 | 1975-05-27 | Squibb & Sons Inc | Penicillin derivatives |
| US4317775A (en) * | 1980-01-07 | 1982-03-02 | Hoffmann-La Roche Inc. | Amoxicillin derivatives |
| FR2495617A1 (fr) * | 1980-12-05 | 1982-06-11 | Dong A Pharm Co Ltd | Procede de preparation de derives d'antibiotiques de la serie des b-lactames, intermediaires nouveaux et procede pour les preparer |
| US6993292B2 (en) * | 2002-02-26 | 2006-01-31 | 3M Innovative Properties Company | Self-monitoring radio network |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2985648A (en) * | 1958-10-06 | 1961-05-23 | Doyle Frank Peter | Alpha-aminobenzylpenicillins |
-
0
- NL NL300841D patent/NL300841A/xx unknown
-
1962
- 1962-11-27 GB GB44728/62A patent/GB980777A/en not_active Expired
-
1963
- 1963-11-19 BR BR154617/63A patent/BR6354617D0/pt unknown
- 1963-11-25 FR FR954869A patent/FR1393286A/fr not_active Expired
- 1963-11-26 FI FI632313A patent/FI42331C/fi active
- 1963-11-26 CH CH1447663A patent/CH435289A/de unknown
- 1963-11-26 AT AT945363A patent/AT249860B/de active
- 1963-11-26 BE BE640432D patent/BE640432A/xx unknown
- 1963-11-26 US US326249A patent/US3230214A/en not_active Expired - Lifetime
- 1963-11-27 ES ES0293930A patent/ES293930A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI42331C (fi) | 1970-07-10 |
| NL300841A (enExample) | 1900-01-01 |
| BR6354617D0 (pt) | 1973-07-12 |
| BE640432A (enExample) | 1964-05-26 |
| FI42331B (enExample) | 1970-03-31 |
| ES293930A1 (es) | 1964-03-01 |
| CH435289A (de) | 1967-05-15 |
| US3230214A (en) | 1966-01-18 |
| FR1393286A (fr) | 1965-03-26 |
| AT249860B (de) | 1966-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1412130A (en) | 3-substituted-morphinan derivatives | |
| ES299038A1 (es) | Procedimiento de preparaciën de nuevas penicilinas | |
| GB980777A (en) | ª‡-amino-substituted penicillins | |
| GB1334705A (en) | Pharmaceutical compositions containing kynurenic acid derivatives | |
| GB1209326A (en) | The preparation of 3-methyl-5-pyrazole carboxylic acid amides | |
| GB991586A (en) | Process for the preparation of penicillins | |
| GB1326360A (en) | Nitrofuryl-pyrazolopyrimidinones | |
| GB1314628A (en) | Method for preparing penicillin sulphoxides | |
| GB1398800A (en) | Trisubstituted imidazoles | |
| GB1244191A (en) | Process for the manufacture of 7-aminocephalosporanic acid | |
| ES410018A1 (es) | Procedimiento para la obtencion de acido benzoxazol-2-car- boxilico. | |
| GB894460A (en) | Improvements in or relating to penicillins | |
| GB1081093A (en) | Improvements in or relating to 6-[d(-)-alpha-(amino-phenylacetamido)]-penicillanic acid derivatives | |
| ES329449A1 (es) | Un procedimiento para la preparacion de penicilinas. | |
| GB1347979A (en) | Penicillins | |
| GB1040166A (en) | Penicillins | |
| ES395419A1 (es) | Un procedimiento para la preparacion de derivados del acido6-aminopenicilanico. | |
| ES398825A1 (es) | Procedimiento para la preparacion de alfa-amino-acil peni- cilinas. | |
| ES356159A1 (es) | Un procedimiento para la preparacion de derivados de acido penicilanico. | |
| ES258756A1 (es) | Proceso para la preparaciën de compuestos de agentes antibacterianos | |
| GB1219848A (en) | NOVEL N-SUBSTITUTED-o-PHENYLENE AMINES, AND PROCESSES FOR THEIR PREPARATION | |
| GB1061566A (en) | Phenoxymethyl penicillins | |
| GB1270741A (en) | Dihydroxyarylene-bis-mercapto-acetic acid bis-lactones | |
| GB1048907A (en) | Penicillins | |
| GB1063364A (en) | Oxazine compounds and the preparation thereof |