GB975495A - Process for the production of alkali metal salts of nitrilo triacetic acid - Google Patents

Process for the production of alkali metal salts of nitrilo triacetic acid

Info

Publication number
GB975495A
GB975495A GB35509/63A GB3550963A GB975495A GB 975495 A GB975495 A GB 975495A GB 35509/63 A GB35509/63 A GB 35509/63A GB 3550963 A GB3550963 A GB 3550963A GB 975495 A GB975495 A GB 975495A
Authority
GB
United Kingdom
Prior art keywords
alkali metal
hydrogen cyanide
formaldehyde
metal salts
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB35509/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB975495A publication Critical patent/GB975495A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Alkali metal salts of nitrilotriacetic acid are prepared by adding a mixture of hydrogen cyanide and formaldehyde to a solution of aqueous ammonia and an alkali metal hydroxide while maintaining the temperature at 40 to 55 DEG C., subsequently raising the temperature to 100-105 DEG C., adding sufficient formaldehyde to eliminate excess hydrogen cyanide and recovering the reaction product. The mixture of hydrogen cyanide and formaldehyde contains an excess of about 10 to 20% of hydrogen cyanide and is added at a constant rate to the aqueous alkaline solution. Sodium hydroxide is the preferred alkali metal hydroxide. Nitrilotriacetic acid may be obtained from its trisodium salt by treatment with hydrochloric acid. Examples describe the preparation of trisodium nitrilotriacetate and its conversion to the free acid. Disodium iminodiacetate and sodium glycinate are obtained as by-products.
GB35509/63A 1962-09-10 1963-09-09 Process for the production of alkali metal salts of nitrilo triacetic acid Expired GB975495A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22261862A 1962-09-10 1962-09-10

Publications (1)

Publication Number Publication Date
GB975495A true GB975495A (en) 1964-11-18

Family

ID=22832984

Family Applications (1)

Application Number Title Priority Date Filing Date
GB35509/63A Expired GB975495A (en) 1962-09-10 1963-09-09 Process for the production of alkali metal salts of nitrilo triacetic acid

Country Status (2)

Country Link
CH (1) CH419165A (en)
GB (1) GB975495A (en)

Also Published As

Publication number Publication date
CH419165A (en) 1966-08-31

Similar Documents

Publication Publication Date Title
US2387735A (en) Method of forming carboxylic amino acids
US3393234A (en) Purification of an alkali metal salt of nitrilotriacetic acid
ES441912A1 (en) Process for the production of pure carboxylic acid-1-monoglycerides
GB1182405A (en) Process for Preparing Sarcosinonitrile
GB975495A (en) Process for the production of alkali metal salts of nitrilo triacetic acid
US3415878A (en) Process for the production of alkali metal salts of nitrilo triacetic acid
SE7501023L (en)
GB976319A (en) Process for the production of alkali metal salts of nitrilo triacetic acid
JPS5668649A (en) Preparation of gamma-amino-beta-hydroxybutyric acid
ES320841A1 (en) Process for preparing azines
GB953387A (en) 5-allyl-5-(ª‰-hydroxypropyl)-barbituric acid and a process for the production thereof
US3833650A (en) Preparation of nitrilotriacetic acid
SU502862A1 (en) The method of producing propylene chlorohydrin
GB854997A (en) Process for the production of hydrazine, hydrazine hydrate or hydrazine salts
ES444508A1 (en) Process for the preparation of phloroglucinol
GB1022733A (en) Triaminobenzene
GB1419335A (en) Process for the production of 1,1,2-triacetoxy ethane
GB1181615A (en) Process for preparing Alkali Metal Nitrilotriacetates
JPS52111496A (en) Production of basic aluminum chloride solution
US3402199A (en) Method for producing threonine
GB814238A (en) Process for the preparation of acrylonitrile
GB887666A (en) Process for the purification of 2-ethyl-cis-crotonoylurea
JPS55122747A (en) Production of iminodiacetic acid derivative
GB1041052A (en) Process for the production of alkynols
GB1199614A (en) Process for Producing 2-Amino-4-Substituted Butyric Acids and the Corresponding Hydantoins