GB973533A - New basic derivatives of 6, 9-endoxo-3-azabicyclo-[4.3.0]-nonane - Google Patents
New basic derivatives of 6, 9-endoxo-3-azabicyclo-[4.3.0]-nonaneInfo
- Publication number
- GB973533A GB973533A GB666462A GB666462A GB973533A GB 973533 A GB973533 A GB 973533A GB 666462 A GB666462 A GB 666462A GB 666462 A GB666462 A GB 666462A GB 973533 A GB973533 A GB 973533A
- Authority
- GB
- United Kingdom
- Prior art keywords
- endoxo
- azabicyclo
- nonane
- reacting
- aminoalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention comprises compounds of general formula <FORM:0973533/C1/1> wherein n is 2 or 3; non-toxic acid addition salts thereof; and their preparation by reacting a corresponding 3-aminoalkyl compound with a compound of formula <FORM:0973533/C1/2> where NX represents an imino group and Y a radical which is easily split off, such as alkylmercapto, alkoxy or a pyrazole radical, or in which X and Y may form together an additional linkage to form a nitrile group. 3-(Aminoalkyl)-6, 9-endoxo-3-azabicyclo-(4,3,0)-nonane starting materials may be obtained by reacting 3, 6-endoxo-hexahydrophthalimide with an appropriate halogenated or unsaturated aliphatic nitrile to form an N-cyanoalkyl-3, 6-endoxohexahydrophthalimide which is then reduced with lithium aluminium hydride.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH306361A CH399467A (en) | 1961-03-14 | 1961-03-14 | Manufacturing process for new basic derivatives of 6,9-endoxo-3-aza-bicyclo- (4.3.0) -nonane |
Publications (1)
Publication Number | Publication Date |
---|---|
GB973533A true GB973533A (en) | 1964-10-28 |
Family
ID=4247788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB666462A Expired GB973533A (en) | 1961-03-14 | 1962-02-21 | New basic derivatives of 6, 9-endoxo-3-azabicyclo-[4.3.0]-nonane |
Country Status (2)
Country | Link |
---|---|
CH (1) | CH399467A (en) |
GB (1) | GB973533A (en) |
-
1961
- 1961-03-14 CH CH306361A patent/CH399467A/en unknown
-
1962
- 1962-02-21 GB GB666462A patent/GB973533A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CH399467A (en) | 1965-09-30 |
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