GB9723835D0 - Interleukin knockout - Google Patents

Interleukin knockout

Info

Publication number
GB9723835D0
GB9723835D0 GBGB9723835.6A GB9723835A GB9723835D0 GB 9723835 D0 GB9723835 D0 GB 9723835D0 GB 9723835 A GB9723835 A GB 9723835A GB 9723835 D0 GB9723835 D0 GB 9723835D0
Authority
GB
United Kingdom
Prior art keywords
knockout
interleukin
interleukin knockout
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9723835.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GBGB9723835.6A priority Critical patent/GB9723835D0/en
Publication of GB9723835D0 publication Critical patent/GB9723835D0/en
Priority to TR2000/01356T priority patent/TR200001356T2/xx
Priority to PCT/US1998/024287 priority patent/WO1999025857A2/en
Priority to EP98962809A priority patent/EP1030926A2/en
Priority to KR1020007005243A priority patent/KR20010015814A/ko
Priority to IL13601398A priority patent/IL136013A0/xx
Priority to AU17966/99A priority patent/AU1796699A/en
Priority to US09/647,826 priority patent/US6437216B1/en
Priority to BR9814142-2A priority patent/BR9814142A/pt
Priority to PL98340829A priority patent/PL340829A1/xx
Priority to CA002309807A priority patent/CA2309807A1/en
Priority to HU0004352A priority patent/HUP0004352A2/hu
Priority to JP2000521220A priority patent/JP2001523467A/ja
Priority to NO20002477A priority patent/NO20002477L/no
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0325—Animal model for autoimmune diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0368—Animal model for inflammation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
GBGB9723835.6A 1997-11-13 1997-11-13 Interleukin knockout Ceased GB9723835D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB9723835.6A GB9723835D0 (en) 1997-11-13 1997-11-13 Interleukin knockout
JP2000521220A JP2001523467A (ja) 1997-11-13 1998-11-13 炎症性疾患のトランスジェニックモデル
AU17966/99A AU1796699A (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
BR9814142-2A BR9814142A (pt) 1997-11-13 1998-11-13 Organismo não humano transgênico, célula ou linha de célula do mesmo, método para produzir um mamìfero não humano com uma interrupção dirigida em um gene antagonista receptor da interleucina-1 (il-1rn), construção nocaute de antagonista receptor il-1, construção nocaute il-1rn e método para testar um agente quanto a efetividade contra uma condição inflamatória.
EP98962809A EP1030926A2 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
KR1020007005243A KR20010015814A (ko) 1997-11-13 1998-11-13 염증 질병의 형질전환된 모델
IL13601398A IL136013A0 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
TR2000/01356T TR200001356T2 (tr) 1997-11-13 1998-11-13 Ateşli hastalıkların transjenerik modelleri
US09/647,826 US6437216B1 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
PCT/US1998/024287 WO1999025857A2 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
PL98340829A PL340829A1 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory diseases
CA002309807A CA2309807A1 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
HU0004352A HUP0004352A2 (en) 1997-11-13 1998-11-13 Transgenic models of inflammatory disease
NO20002477A NO20002477L (no) 1997-11-13 2000-05-12 Transgene modeller av inflammatoriske sykdommer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9723835.6A GB9723835D0 (en) 1997-11-13 1997-11-13 Interleukin knockout

Publications (1)

Publication Number Publication Date
GB9723835D0 true GB9723835D0 (en) 1998-01-07

Family

ID=10821919

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9723835.6A Ceased GB9723835D0 (en) 1997-11-13 1997-11-13 Interleukin knockout

Country Status (13)

Country Link
EP (1) EP1030926A2 (ja)
JP (1) JP2001523467A (ja)
KR (1) KR20010015814A (ja)
AU (1) AU1796699A (ja)
BR (1) BR9814142A (ja)
CA (1) CA2309807A1 (ja)
GB (1) GB9723835D0 (ja)
HU (1) HUP0004352A2 (ja)
IL (1) IL136013A0 (ja)
NO (1) NO20002477L (ja)
PL (1) PL340829A1 (ja)
TR (1) TR200001356T2 (ja)
WO (1) WO1999025857A2 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437216B1 (en) 1997-11-13 2002-08-20 Interleukin Genetics Inc. Transgenic models of inflammatory disease
WO2001056606A1 (fr) * 2000-01-31 2001-08-09 Santen Pharmaceutical Co., Ltd. Remedes pour troubles ophtalmiques
KR20030067204A (ko) * 2002-02-07 2003-08-14 한국생명공학연구원 퍼록시레독신-ⅱ 유전자 결손 생쥐 및 이의 생산방법
WO2005078098A1 (en) * 2004-02-12 2005-08-25 The Walter And Eliza Hall Institute Of Medical Research Modified cells that co-express blimp1 and a reporter molecule and methods of using the same
JP2009183176A (ja) * 2008-02-05 2009-08-20 Univ Of Tokyo Ｉｌ−１タイプｉｉレセプター遺伝子の欠損変異体マウス
JP5186637B2 (ja) * 2009-07-30 2013-04-17 国立大学法人富山大学 トランスジェニック非ヒト哺乳動物およびその利用
WO2019235839A1 (ko) * 2018-06-05 2019-12-12 사회복지법인 삼성생명공익재단 그레이브스 안병증 표현형 동물 모델, 그의 제조방법 및 그레이브스 안병증 치료물질 스크리닝 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1269989B (it) * 1994-09-21 1997-04-16 Dompe Spa Antagonisti recettoriali di il-1 ad aumentata attivita' inibitoria
JPH10507637A (ja) * 1994-10-20 1998-07-28 メルク エンド カンパニー インコーポレーテッド インターロイキン−１β欠損トランスジェニック動物
US6210877B1 (en) * 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease

Also Published As

Publication number Publication date
IL136013A0 (en) 2001-05-20
BR9814142A (pt) 2000-10-03
JP2001523467A (ja) 2001-11-27
AU1796699A (en) 1999-06-07
TR200001356T2 (tr) 2000-08-21
NO20002477D0 (no) 2000-05-12
WO1999025857A3 (en) 1999-07-15
PL340829A1 (en) 2001-02-26
NO20002477L (no) 2000-07-12
EP1030926A2 (en) 2000-08-30
CA2309807A1 (en) 1999-05-27
HUP0004352A2 (en) 2001-03-28
KR20010015814A (ko) 2001-02-26
WO1999025857A2 (en) 1999-05-27

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)