GB968870A - Esters of the androstane series and process for their manufacture - Google Patents
Esters of the androstane series and process for their manufactureInfo
- Publication number
- GB968870A GB968870A GB1801/61A GB180161A GB968870A GB 968870 A GB968870 A GB 968870A GB 1801/61 A GB1801/61 A GB 1801/61A GB 180161 A GB180161 A GB 180161A GB 968870 A GB968870 A GB 968870A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetate
- methallyl
- give
- monosulphobenzoic
- diol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001441 androstanes Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 methallyl magnesium chloride Chemical compound 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- CBMYJHIOYJEBSB-WZDBAGNOSA-N (5s,8r,9s,10s,13s,14s)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthrene-3,17-diol Chemical class C1C(O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)O)[C@@H]4[C@@H]3CC[C@H]21 CBMYJHIOYJEBSB-WZDBAGNOSA-N 0.000 abstract 1
- SBNLPRGISFUZQE-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical class C1C=C2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 SBNLPRGISFUZQE-VMXHOPILSA-N 0.000 abstract 1
- ZMPRRFPMMJQXPP-UHFFFAOYSA-N 2-sulfobenzoic acid Chemical class OC(=O)C1=CC=CC=C1S(O)(=O)=O ZMPRRFPMMJQXPP-UHFFFAOYSA-N 0.000 abstract 1
- QMWGSOMVXSRXQX-UHFFFAOYSA-N 3-sulfobenzoic acid Chemical class OC(=O)C1=CC=CC(S(O)(=O)=O)=C1 QMWGSOMVXSRXQX-UHFFFAOYSA-N 0.000 abstract 1
- HWAQOZGATRIYQG-UHFFFAOYSA-N 4-sulfobenzoic acid Chemical class OC(=O)C1=CC=C(S(O)(=O)=O)C=C1 HWAQOZGATRIYQG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- QADHLRWLCPCEKT-LOVVWNRFSA-N androst-5-ene-3beta,17beta-diol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC=C21 QADHLRWLCPCEKT-LOVVWNRFSA-N 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000002804 anti-anaphylactic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L magnesium chloride Substances [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 1
- 229950005326 prasterone acetate Drugs 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH37560A CH383362A (de) | 1960-01-14 | 1960-01-14 | Verfahren zur Herstellung von neuen Estern der Androstanreihe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB968870A true GB968870A (en) | 1964-09-02 |
Family
ID=4185579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1801/61A Expired GB968870A (en) | 1960-01-14 | 1961-01-16 | Esters of the androstane series and process for their manufacture |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH383362A (enExample) |
| FR (2) | FR944M (enExample) |
| GB (1) | GB968870A (enExample) |
-
1960
- 1960-01-14 CH CH37560A patent/CH383362A/de unknown
-
1961
- 1961-01-16 GB GB1801/61A patent/GB968870A/en not_active Expired
- 1961-02-20 FR FR853218A patent/FR944M/fr active Active
- 1961-03-28 FR FR856970A patent/FR1029M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1029M (fr) | 1962-01-02 |
| CH383362A (de) | 1964-10-31 |
| FR944M (enExample) | 1961-11-20 |
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