GB964449A - Derivatives of 6-amino penicillanic acid - Google Patents
Derivatives of 6-amino penicillanic acidInfo
- Publication number
- GB964449A GB964449A GB6084962A GB6084962A GB964449A GB 964449 A GB964449 A GB 964449A GB 6084962 A GB6084962 A GB 6084962A GB 6084962 A GB6084962 A GB 6084962A GB 964449 A GB964449 A GB 964449A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- compound
- radical
- formula
- trimethylsilyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical class [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 6
- -1 alkyl radical Chemical class 0.000 abstract 4
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 4
- FFUAGWLWBBFQJT-UHFFFAOYSA-N hexamethyldisilazane Chemical compound C[Si](C)(C)N[Si](C)(C)C FFUAGWLWBBFQJT-UHFFFAOYSA-N 0.000 abstract 4
- 150000003254 radicals Chemical class 0.000 abstract 4
- 229930182555 Penicillin Natural products 0.000 abstract 3
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 2
- 238000006136 alcoholysis reaction Methods 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000005051 trimethylchlorosilane Substances 0.000 abstract 2
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001805 chlorine compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 229910052710 silicon Inorganic materials 0.000 abstract 1
- 239000010703 silicon Substances 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEC23708A DE1159449B (de) | 1961-03-22 | 1961-03-22 | Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen |
| DEC0025516 | 1961-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB964449A true GB964449A (en) | 1964-07-22 |
Family
ID=25969395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6084962A Expired GB964449A (en) | 1961-03-22 | 1962-03-21 | Derivatives of 6-amino penicillanic acid |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH421110A (enExample) |
| DK (1) | DK120595B (enExample) |
| GB (1) | GB964449A (enExample) |
| MY (1) | MY6900129A (enExample) |
| SE (1) | SE322512B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2100925A1 (enExample) * | 1970-07-17 | 1972-03-24 | Hoffmann La Roche | |
| US4182709A (en) * | 1976-01-15 | 1980-01-08 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
-
1962
- 1962-03-05 SE SE239562A patent/SE322512B/xx unknown
- 1962-03-20 CH CH328262A patent/CH421110A/de unknown
- 1962-03-21 DK DK130162A patent/DK120595B/da unknown
- 1962-03-21 GB GB6084962A patent/GB964449A/en not_active Expired
-
1969
- 1969-12-31 MY MY6900129A patent/MY6900129A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2100925A1 (enExample) * | 1970-07-17 | 1972-03-24 | Hoffmann La Roche | |
| US4182709A (en) * | 1976-01-15 | 1980-01-08 | Glaxo Group Limited | Manufacture of semi-synthetic penicillin antibiotics |
Also Published As
| Publication number | Publication date |
|---|---|
| MY6900129A (en) | 1969-12-31 |
| SE322512B (enExample) | 1970-04-13 |
| DK120595B (da) | 1971-06-21 |
| CH421110A (de) | 1966-09-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3499909A (en) | Process for production of 6-aminopenicillanic acid | |
| GB1340208A (en) | Process for producing 6-aminopenicillanic acid | |
| GB964449A (en) | Derivatives of 6-amino penicillanic acid | |
| GB1339605A (en) | Penicillin synthesis | |
| GB1008468A (en) | N-substituted 6-amino penicillanic acids | |
| KR830001945A (ko) | β-락탐을 함유하는 항박테리아제 및 β-락타메이즈 억제물질의 제조방법 | |
| US3676429A (en) | Imino compounds of penicillins and silyl esters thereof | |
| ES385437A1 (es) | Metodo para la preparacion de nuevos derivados de acido pe-nicilanico. | |
| GB959853A (en) | Penicillins | |
| GB1297299A (enExample) | ||
| ES395922A1 (es) | Un procedimiento para la produccion de acidos 7-aminocefa- losporanicos. | |
| GB1431327A (en) | Cephalosporins and methods of production | |
| SE7908285L (sv) | Forbettringar vid eller med avseende pa framstellning av halvsyntetiska penicillinantibiotika | |
| GB653238A (en) | A process for the manufacture of alkoxy chlorosilanes | |
| ES484320A1 (es) | Un procedimiento para la preparacion de cefalosporinas | |
| ATE18194T1 (de) | Verfahren zur herstellung von carbonsaeureanhydriden. | |
| GB1361525A (en) | Colour stabilization of dicarboxylic acid anhydrides | |
| GB876708A (en) | Process for producing alkylhydrosilanes | |
| GB1185918A (en) | Bifunctional Carboxylic Acid Halides and a Process for their Production | |
| GB1049031A (en) | Malonic acid derivatives | |
| GB1254339A (en) | Quinoxaline-di-n-oxide-lactones | |
| GB961627A (en) | Penicillins | |
| IE42384L (en) | Oxothiodimethylamides | |
| GB993826A (en) | Resinous compositions | |
| GB960896A (en) | Production of penicillins |