ES484320A1 - Un procedimiento para la preparacion de cefalosporinas - Google Patents
Un procedimiento para la preparacion de cefalosporinasInfo
- Publication number
- ES484320A1 ES484320A1 ES484320A ES484320A ES484320A1 ES 484320 A1 ES484320 A1 ES 484320A1 ES 484320 A ES484320 A ES 484320A ES 484320 A ES484320 A ES 484320A ES 484320 A1 ES484320 A1 ES 484320A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- group
- cephalosporin
- phosphonocarbamoyloxymethyl
- alicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 5
- 229940124587 cephalosporin Drugs 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- -1 cephalosporin compounds Chemical class 0.000 title abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 4
- 125000002723 alicyclic group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Un procedimiento para la preparación de cefalosporinas que tienen un grupo fosfonocarbamoiloximetilo en la posición 3, así como de sus sales, que comprende hacer reaccionar una cefalosporina que tiene en la posición 3 un grupo de formula **fórmula ** (En la que R4 y R5 , que pueden ser iguales o diferentes, representan cada uno un grupo alcohilo, aralcohilo, aliciclico o arilo o R4 y R5 forman juntos un grupo divalente con al menos tres átomos de carbono que unen los átomos de oxigeno) con un compuesto de fórmula **fórmula** (en la que R6, R7 y r8 , que pueden ser iguales o diferentes, representan cada uno un grupo alcohilo, aralcohilo, alicíclico o arilo, y dos cuales quiera de R6, R7 y R8 forman juntos un grupo divalente, que contiene al menos átomos de carbono, y X representa un átomo de cloro, bromo o yodo) seguido de hidrólisis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7837675 | 1978-09-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484320A1 true ES484320A1 (es) | 1980-10-01 |
Family
ID=10499829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484320A Expired ES484320A1 (es) | 1978-09-21 | 1979-09-20 | Un procedimiento para la preparacion de cefalosporinas |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4284766A (es) |
| JP (1) | JPS5559194A (es) |
| AT (1) | AT365195B (es) |
| BE (1) | BE878898A (es) |
| DE (1) | DE2937951A1 (es) |
| DK (1) | DK392779A (es) |
| ES (1) | ES484320A1 (es) |
| FR (1) | FR2436788A1 (es) |
| IT (1) | IT1162665B (es) |
| NL (1) | NL7906999A (es) |
| SE (1) | SE7907814L (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8005041A (nl) * | 1980-09-05 | 1982-04-01 | Gist Brocades Nv | Werkwijze voor de bereiding van thioethers, alsmede gesilyleerde thiolen voor toepassing bij deze werkwijze. |
| YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
| AT411996B (de) * | 2000-09-11 | 2004-08-26 | Sandoz Ag | Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1128930A (en) * | 1978-04-07 | 1982-08-03 | Stuart B. Laing | Cephalosporin compounds |
-
1979
- 1979-09-20 US US06/077,757 patent/US4284766A/en not_active Expired - Lifetime
- 1979-09-20 DE DE19792937951 patent/DE2937951A1/de not_active Withdrawn
- 1979-09-20 BE BE0/197234A patent/BE878898A/fr unknown
- 1979-09-20 IT IT50308/79A patent/IT1162665B/it active
- 1979-09-20 SE SE7907814A patent/SE7907814L/ not_active Application Discontinuation
- 1979-09-20 NL NL7906999A patent/NL7906999A/nl not_active Application Discontinuation
- 1979-09-20 JP JP12021279A patent/JPS5559194A/ja active Pending
- 1979-09-20 FR FR7923470A patent/FR2436788A1/fr active Granted
- 1979-09-20 DK DK392779A patent/DK392779A/da not_active Application Discontinuation
- 1979-09-20 AT AT0619779A patent/AT365195B/de not_active IP Right Cessation
- 1979-09-20 ES ES484320A patent/ES484320A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2436788B1 (es) | 1984-03-09 |
| DK392779A (da) | 1980-03-22 |
| ATA619779A (de) | 1981-05-15 |
| DE2937951A1 (de) | 1980-04-17 |
| AT365195B (de) | 1981-12-28 |
| SE7907814L (sv) | 1980-03-22 |
| JPS5559194A (en) | 1980-05-02 |
| BE878898A (fr) | 1980-03-20 |
| NL7906999A (nl) | 1980-03-25 |
| US4284766A (en) | 1981-08-18 |
| IT1162665B (it) | 1987-04-01 |
| IT7950308A0 (it) | 1979-09-20 |
| FR2436788A1 (fr) | 1980-04-18 |
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