GB962943A - Improvements in or relating to the preparation of penicillins - Google Patents

Improvements in or relating to the preparation of penicillins

Info

Publication number
GB962943A
GB962943A GB568862A GB568862A GB962943A GB 962943 A GB962943 A GB 962943A GB 568862 A GB568862 A GB 568862A GB 568862 A GB568862 A GB 568862A GB 962943 A GB962943 A GB 962943A
Authority
GB
United Kingdom
Prior art keywords
penicillins
phenyl
carbobenzoxy
relating
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB568862A
Inventor
Emilio Testa
Giorgio Cignarella
Giorgio Pifferi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Priority to GB568862A priority Critical patent/GB962943A/en
Priority to BR14113362A priority patent/BR6241133D0/en
Priority to ES0280754A priority patent/ES280754A1/en
Priority to NO14572162A priority patent/NO119272B/no
Priority to BR14313362A priority patent/BR6243133D0/en
Priority to SE10276/62A priority patent/SE308313B/en
Priority to CH1127062A priority patent/CH398601A/en
Publication of GB962943A publication Critical patent/GB962943A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Penicillins of the general formula: <FORM:0962943/C1/1> wherein X represents an alkylene group may be prepared by reacting 6-aminopenicillamic acid with a mixed anhydride obtained from the appropriate a -phenyl-o -carbobenzoxy-aminoacid and an ester of chlorocarbonic acid, in the presence of a tertiary amine and splitting off the carbobenzoxy group by catalytic hydrogenation. Examples describe the production of (-)-b -amino-a -phenylethyl-, a -phenyl-g -aminopropyl- and a -phenyl-d -aminobutyl-penicillins. Specification 960,896 is referred to.
GB568862A 1962-02-14 1962-02-14 Improvements in or relating to the preparation of penicillins Expired GB962943A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GB568862A GB962943A (en) 1962-02-14 1962-02-14 Improvements in or relating to the preparation of penicillins
BR14113362A BR6241133D0 (en) 1962-02-14 1962-07-19 NEW MARINE DEVICES
ES0280754A ES280754A1 (en) 1962-02-14 1962-09-13 Improvements in or relating to the preparation of penicillins
NO14572162A NO119272B (en) 1962-02-14 1962-09-14
BR14313362A BR6243133D0 (en) 1962-02-14 1962-09-17 NEW PHARMACOLOGICALLY ACTIVE COMPOUNDS AND PREPARATION PROCESS
SE10276/62A SE308313B (en) 1962-02-14 1962-09-25 Method of preparing penicillin derivatives
CH1127062A CH398601A (en) 1962-02-14 1962-09-25 Process for the preparation of pharmacologically active compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB568862A GB962943A (en) 1962-02-14 1962-02-14 Improvements in or relating to the preparation of penicillins

Publications (1)

Publication Number Publication Date
GB962943A true GB962943A (en) 1964-07-08

Family

ID=9800780

Family Applications (1)

Application Number Title Priority Date Filing Date
GB568862A Expired GB962943A (en) 1962-02-14 1962-02-14 Improvements in or relating to the preparation of penicillins

Country Status (6)

Country Link
BR (2) BR6241133D0 (en)
CH (1) CH398601A (en)
ES (1) ES280754A1 (en)
GB (1) GB962943A (en)
NO (1) NO119272B (en)
SE (1) SE308313B (en)

Also Published As

Publication number Publication date
SE308313B (en) 1969-02-10
BR6241133D0 (en) 1973-05-31
ES280754A1 (en) 1963-02-01
NO119272B (en) 1970-04-27
CH398601A (en) 1966-03-15
BR6243133D0 (en) 1973-06-14

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