Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21864/61A
Inventor
Livio Zeller-Celso
Amato Vitangelo D
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Gruppo Lepetit SpA
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Lepetit SpA
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Publication date
Application filed by Lepetit SpAfiledCriticalLepetit SpA
Priority to GB21864/61ApriorityCriticalpatent/GB950515A/en
Publication of GB950515ApublicationCriticalpatent/GB950515A/en
C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
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Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Chemical Kinetics & Catalysis
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
The invention comprises chloramphenicol hemidiglycolate of the formula: <FORM:0950515/C2/1> and its preparation by reacting, at -15 to 0 DEG C., diglycolic anhydride with chloramphenicol in anhydrous pyridine. Pharmaceutical compositions of the watersoluble antibiotic ester are mentioned for parenteral administration in liquid form.
Procedure for the preparation of new derivatives of the acid range-trimethylamine - beta - hydroxibutirico with therapeutic properties. (Machine-translation by Google Translate, not legally binding)