GB949988A - Preparation of salcicylic acid and its alkali metal salts - Google Patents

Preparation of salcicylic acid and its alkali metal salts

Info

Publication number
GB949988A
GB949988A GB2145261A GB2145261A GB949988A GB 949988 A GB949988 A GB 949988A GB 2145261 A GB2145261 A GB 2145261A GB 2145261 A GB2145261 A GB 2145261A GB 949988 A GB949988 A GB 949988A
Authority
GB
United Kingdom
Prior art keywords
phenate
phenol
alkali metal
solution
metal salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2145261A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of GB949988A publication Critical patent/GB949988A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Salicylic acid and its alkali metal salts are prepared by the carboxylation of an alkali metal phenate in the presence of a substantial proportion of phenol wherein the carboxylation reaction is carried out at a temperature in the range of 140 DEG to 175 DEG C. under a pressure of 2 to 36 atmospheres absolute using an anhydrous phenolphenate solution which is vigorously stirred to provide fresh solution surfaces for the carbon dioxide absorption and combination with the phenate. The process is preferably continuous, the unreacted phenol-phenate solution being recycled. The product is recovered by sedimentation and filtration and is preferably washed with solvents such as toluene, xylene or chlorobenzenes the filtrate being used to dry the phenol-phenate starting material by azeotropic distillation. In an example a mixture of 1 mole of sodium phenate and 3.5 moles of phenol is dried by azeotropic distillation and carbonated at 165 DEG C. under 5 atmospheres pressure for 1 hour with stirring to give sodium salicylate. Specifications 384,619 and 774,387 are referred to.
GB2145261A 1960-06-17 1961-06-14 Preparation of salcicylic acid and its alkali metal salts Expired GB949988A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3674760A 1960-06-17 1960-06-17

Publications (1)

Publication Number Publication Date
GB949988A true GB949988A (en) 1964-02-19

Family

ID=21890412

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2145261A Expired GB949988A (en) 1960-06-17 1961-06-14 Preparation of salcicylic acid and its alkali metal salts

Country Status (2)

Country Link
DE (1) DE1215173B (en)
GB (1) GB949988A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072095A1 (en) * 1981-07-07 1983-02-16 Gert Jansen Production of sodium salicylate
CN113416137A (en) * 2021-06-22 2021-09-21 宁夏万香源生物科技有限公司 Preparation method of benzyl salicylate
CN114874092A (en) * 2022-06-13 2022-08-09 扬州大学 Method for preparing sodium salicylate through sodium phenolate carboxylation reaction

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109553236A (en) * 2018-05-31 2019-04-02 张庆华 The process flow containing ammonia nitrogen, phenol wastewater is administered in controllable concentration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824892A (en) * 1956-04-02 1958-02-25 Monsanto Chemicals Method of carboxylating phenols

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072095A1 (en) * 1981-07-07 1983-02-16 Gert Jansen Production of sodium salicylate
CN113416137A (en) * 2021-06-22 2021-09-21 宁夏万香源生物科技有限公司 Preparation method of benzyl salicylate
CN113416137B (en) * 2021-06-22 2024-01-02 宁夏万香源生物科技有限公司 Preparation method of benzyl salicylate
CN114874092A (en) * 2022-06-13 2022-08-09 扬州大学 Method for preparing sodium salicylate through sodium phenolate carboxylation reaction

Also Published As

Publication number Publication date
DE1215173B (en) 1966-04-28

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