GB855880A - Production of alpha hydroxyisobutyric acid - Google Patents
Production of alpha hydroxyisobutyric acidInfo
- Publication number
- GB855880A GB855880A GB1353857A GB1353857A GB855880A GB 855880 A GB855880 A GB 855880A GB 1353857 A GB1353857 A GB 1353857A GB 1353857 A GB1353857 A GB 1353857A GB 855880 A GB855880 A GB 855880A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxidation
- acid
- hydrolysis
- hydroxyisobutyric acid
- dinitrogen tetroxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/02—Preparation of esters of nitric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
- C07C51/27—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with oxides of nitrogen or nitrogen-containing mineral acids
- C07C51/275—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with oxides of nitrogen or nitrogen-containing mineral acids of hydrocarbyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
a -Hydroxyisobutyric acid is produced by reacting isobutylene with dinitrogen tetroxide in a mole ratio of at least one mole of dinitrogen tetroxide per mole of isobutylene at a temperature below 40 DEG C. to produce a -nitratoisobutyric anhydride or a -nitratoisobutyraldehyde and mixtures thereof, and converting these products by oxidation and hydrolysis into a -hydroxyisobutyric acid. The dinitrogen tetroxide may be employed in the form of a mixture with dinitrogen trioxide. The further oxidation and/or hydrolysis of the intermediates may be carried out at temperatures between 0 DEG C. and 150 DEG C. The intermediates may be separated from the reaction mixture and subsequently converted or they may be treated in situ. Thus the only further treatment may be an additional standing at an elevated temperature. Nitric acid may be added to facilitate the oxidation and the hydrolysis may be accomplished by use of water, aqueous acid solutions or aqueous alkali metal hydroxide solutions. The oxidation and hydrolysis may be carried out separately or as one step. Subsequent to the oxidation there can be recovered both a -nitrato- and a -hydroxyisobutyric acid. The a -nitratoisobutyric acid may be precipitated selectively by cooling the reaction mixture, and the resulting solution may be evaporated to obtain a -hydroxyisobutyric acid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1353857A GB855880A (en) | 1957-04-29 | 1957-04-29 | Production of alpha hydroxyisobutyric acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1353857A GB855880A (en) | 1957-04-29 | 1957-04-29 | Production of alpha hydroxyisobutyric acid |
Publications (1)
Publication Number | Publication Date |
---|---|
GB855880A true GB855880A (en) | 1960-12-07 |
Family
ID=10024793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1353857A Expired GB855880A (en) | 1957-04-29 | 1957-04-29 | Production of alpha hydroxyisobutyric acid |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB855880A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3449385A (en) * | 1965-10-12 | 1969-06-10 | Chemie Linz Ag | Process for the manufacture of aliphatic alpha-hydroxycarboxylic acids |
-
1957
- 1957-04-29 GB GB1353857A patent/GB855880A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3449385A (en) * | 1965-10-12 | 1969-06-10 | Chemie Linz Ag | Process for the manufacture of aliphatic alpha-hydroxycarboxylic acids |
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