GB947494A - New dialkyl xanthine derivatives and a process for the preparation thereof - Google Patents
New dialkyl xanthine derivatives and a process for the preparation thereofInfo
- Publication number
- GB947494A GB947494A GB14251/60A GB1425160A GB947494A GB 947494 A GB947494 A GB 947494A GB 14251/60 A GB14251/60 A GB 14251/60A GB 1425160 A GB1425160 A GB 1425160A GB 947494 A GB947494 A GB 947494A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- xanthine
- dialkyl
- benzyl
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229940083747 low-ceiling diuretics xanthine derivative Drugs 0.000 title 1
- 229940075420 xanthine Drugs 0.000 abstract 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14251/60A GB947494A (en) | 1960-04-22 | 1960-04-22 | New dialkyl xanthine derivatives and a process for the preparation thereof |
| LU40044A LU40044A1 (enrdf_load_stackoverflow) | 1960-04-22 | 1961-04-20 | |
| BE602887A BE602887A (fr) | 1960-04-22 | 1961-04-21 | Nouveaux dérivés de 8-benzylxanthines et leur préparation. |
| CH471761A CH417605A (fr) | 1960-04-22 | 1961-04-21 | Procédé de préparation de dérivés de la 8-benzylxanthine |
| ES0266787A ES266787A1 (es) | 1960-04-22 | 1961-04-21 | Un procedimiento de preparar un derivado de 8-bencil xantina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14251/60A GB947494A (en) | 1960-04-22 | 1960-04-22 | New dialkyl xanthine derivatives and a process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB947494A true GB947494A (en) | 1964-01-22 |
Family
ID=10037767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB14251/60A Expired GB947494A (en) | 1960-04-22 | 1960-04-22 | New dialkyl xanthine derivatives and a process for the preparation thereof |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE602887A (enrdf_load_stackoverflow) |
| CH (1) | CH417605A (enrdf_load_stackoverflow) |
| ES (1) | ES266787A1 (enrdf_load_stackoverflow) |
| GB (1) | GB947494A (enrdf_load_stackoverflow) |
| LU (1) | LU40044A1 (enrdf_load_stackoverflow) |
-
1960
- 1960-04-22 GB GB14251/60A patent/GB947494A/en not_active Expired
-
1961
- 1961-04-20 LU LU40044A patent/LU40044A1/xx unknown
- 1961-04-21 ES ES0266787A patent/ES266787A1/es not_active Expired
- 1961-04-21 CH CH471761A patent/CH417605A/fr unknown
- 1961-04-21 BE BE602887A patent/BE602887A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE602887A (fr) | 1961-10-23 |
| CH417605A (fr) | 1966-07-31 |
| ES266787A1 (es) | 1961-12-01 |
| LU40044A1 (enrdf_load_stackoverflow) | 1961-10-20 |
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