GB924014A - New hemiacetals and hemiacetal esters of the androstane series and a method for their production - Google Patents

New hemiacetals and hemiacetal esters of the androstane series and a method for their production

Info

Publication number
GB924014A
GB924014A GB22062/60A GB2206260A GB924014A GB 924014 A GB924014 A GB 924014A GB 22062/60 A GB22062/60 A GB 22062/60A GB 2206260 A GB2206260 A GB 2206260A GB 924014 A GB924014 A GB 924014A
Authority
GB
United Kingdom
Prior art keywords
group
hydroxy group
hemiacetal
radical
ochr6r7
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB22062/60A
Inventor
Poul Borrevang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KNUD ABILDGAARD
Original Assignee
KNUD ABILDGAARD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KNUD ABILDGAARD filed Critical KNUD ABILDGAARD
Priority to GB22062/60A priority Critical patent/GB924014A/en
Priority to AT472261A priority patent/AT242872B/en
Priority to CH732461A priority patent/CH406203A/en
Priority to NL266255A priority patent/NL107269C/xx
Priority to BE605291A priority patent/BE605291A/en
Priority to ES0268561A priority patent/ES268561A1/en
Priority to FR873408A priority patent/FR1326M/en
Publication of GB924014A publication Critical patent/GB924014A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises steroid hemiacetals of the general formulae:- <FORM:0924014/IV(a)/1> <FORM:0924014/IV(a)/2> (in which R1 is a hydrogen atom, a lower saturated aliphatic group or an unsaturated group, the said group containing not more than 3 carbon atoms; R2 is a b -hydroxy group or a radical connected in the b -position to the steroid molecule and having the formula:-OCHR6R7, in which R6 is an aliphatic radical unsubstituted or substituted with halogen atoms or aromatic or heterocyclic groups, and R7 is a free or esterified hydroxy group; R3 is a hydrogen atom or, together with R4, an oxygen atom, R4 is an a -hydroxy group, a b -hydroxy group or the radical -OCHR6R7, provided that when R2 is not -OCHR6R7, R4 must be the said radical; R5 is a hydrogen or halogen atom or a hydroxy group; y is a single or double bond, and x is a single bond when y is a single bond, and either a single or a double bond when y is a double bond) testosterone chloral-hemiacetal and testosterone chloral-hemiacetal esters being excluded, together with a process for their preparation by reacting a compound of the above general formulae (in which R2 is a b -hydroxy group and R4 is an a -hydroxy group, a b -hydroxy group or together with R3 is an oxygen atom, the other symbols being as defined above) with an aliphatic aldehyde, or its hydrate, which may contain as substituents at least halogen atoms, an aromatic group including a phenoxy group, or a heterocyclic group, and recovering the hemiacetal or dihemiacetal produced. The invention is illustrated by 23 detailed examples. The Provisional Specification refers to Specification 862,531.
GB22062/60A 1960-06-23 1960-06-23 New hemiacetals and hemiacetal esters of the androstane series and a method for their production Expired GB924014A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GB22062/60A GB924014A (en) 1960-06-23 1960-06-23 New hemiacetals and hemiacetal esters of the androstane series and a method for their production
AT472261A AT242872B (en) 1960-06-23 1961-06-19 Process for the production of new derivatives of the androstane series
CH732461A CH406203A (en) 1960-06-23 1961-06-22 Process for the production of new derivatives of the androstane series
NL266255A NL107269C (en) 1960-06-23 1961-06-22
BE605291A BE605291A (en) 1960-06-23 1961-06-22 New derivatives of the androstane series and method for the production of these derivatives.
ES0268561A ES268561A1 (en) 1960-06-23 1961-06-23 New hemiacetals and hemiacetal esters of the androstane series and a method for their production
FR873408A FR1326M (en) 1960-06-23 1961-09-16 3- or 17-semiacetals or 3,17-disemiacetals of steroids of the androstane series.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB22062/60A GB924014A (en) 1960-06-23 1960-06-23 New hemiacetals and hemiacetal esters of the androstane series and a method for their production

Publications (1)

Publication Number Publication Date
GB924014A true GB924014A (en) 1963-04-18

Family

ID=10173292

Family Applications (1)

Application Number Title Priority Date Filing Date
GB22062/60A Expired GB924014A (en) 1960-06-23 1960-06-23 New hemiacetals and hemiacetal esters of the androstane series and a method for their production

Country Status (7)

Country Link
AT (1) AT242872B (en)
BE (1) BE605291A (en)
CH (1) CH406203A (en)
ES (1) ES268561A1 (en)
FR (1) FR1326M (en)
GB (1) GB924014A (en)
NL (1) NL107269C (en)

Also Published As

Publication number Publication date
NL107269C (en) 1963-12-17
CH406203A (en) 1966-01-31
ES268561A1 (en) 1962-04-01
FR1326M (en) 1962-05-21
AT242872B (en) 1965-10-11
BE605291A (en) 1961-12-22

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