GB923414A - Therapeutic compositions comprising asiatic and arjunolic acids - Google Patents
Therapeutic compositions comprising asiatic and arjunolic acidsInfo
- Publication number
- GB923414A GB923414A GB13220/60A GB1322060A GB923414A GB 923414 A GB923414 A GB 923414A GB 13220/60 A GB13220/60 A GB 13220/60A GB 1322060 A GB1322060 A GB 1322060A GB 923414 A GB923414 A GB 923414A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- ethanol
- arjunolic
- asiatic
- asiaticoside
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 16
- 235000019441 ethanol Nutrition 0.000 abstract 7
- RWNHLTKFBKYDOJ-DDHMHSPCSA-N arjunolic acid Chemical compound C1[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C RWNHLTKFBKYDOJ-DDHMHSPCSA-N 0.000 abstract 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 4
- RWNHLTKFBKYDOJ-UHFFFAOYSA-N (-)-arjunolic acid Natural products C1C(O)C(O)C(C)(CO)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C RWNHLTKFBKYDOJ-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- WYQVAPGDARQUBT-FGWHUCSPSA-N Madecassol Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(CC[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O WYQVAPGDARQUBT-FGWHUCSPSA-N 0.000 abstract 2
- JXSVIVRDWWRQRT-UYDOISQJSA-N asiatic acid Chemical compound C1[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C JXSVIVRDWWRQRT-UYDOISQJSA-N 0.000 abstract 2
- LBGFKBYMNRAMFC-PYSQTNCISA-N asiatic acid Natural products C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@]2(C)[C@H]1C)C(=O)O LBGFKBYMNRAMFC-PYSQTNCISA-N 0.000 abstract 2
- WYQVAPGDARQUBT-XCWYDTOWSA-N asiaticoside Natural products O=C(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](CO)O2)O1)[C@@]12[C@@H]([C@@H](C)[C@H](C)CC1)C=1[C@](C)([C@@]3(C)[C@@H]([C@@]4(C)[C@H]([C@@](CO)(C)[C@@H](O)[C@H](O)C4)CC3)CC=1)CC2 WYQVAPGDARQUBT-XCWYDTOWSA-N 0.000 abstract 2
- 229940022757 asiaticoside Drugs 0.000 abstract 2
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 abstract 2
- CLXOLTFMHAXJST-UHFFFAOYSA-N esculentic acid Natural products C12CC=C3C4CC(C)(C(O)=O)CCC4(C(O)=O)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(CO)C CLXOLTFMHAXJST-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 244000146462 Centella asiatica Species 0.000 abstract 1
- 235000004032 Centella asiatica Nutrition 0.000 abstract 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 235000010654 Melissa officinalis Nutrition 0.000 abstract 1
- 244000062730 Melissa officinalis Species 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 241001534869 Terminalia Species 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940011658 asiatic acid Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000865 liniment Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000003182 parenteral nutrition solution Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB13220/60A GB923414A (en) | 1960-04-13 | 1960-04-13 | Therapeutic compositions comprising asiatic and arjunolic acids |
| FR850453A FR884M (enrdf_load_stackoverflow) | 1960-04-13 | 1961-01-23 | |
| FR850454A FR885M (enrdf_load_stackoverflow) | 1960-04-13 | 1961-01-23 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB13220/60A GB923414A (en) | 1960-04-13 | 1960-04-13 | Therapeutic compositions comprising asiatic and arjunolic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB923414A true GB923414A (en) | 1963-04-10 |
Family
ID=10019010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13220/60A Expired GB923414A (en) | 1960-04-13 | 1960-04-13 | Therapeutic compositions comprising asiatic and arjunolic acids |
Country Status (2)
| Country | Link |
|---|---|
| FR (2) | FR884M (enrdf_load_stackoverflow) |
| GB (1) | GB923414A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4606911A (en) * | 1984-07-27 | 1986-08-19 | Rohto Pharmaceutical Co. Ltd. | Pharmaceutical composition for the prevention of dental caries |
| WO1998023278A1 (en) * | 1996-11-27 | 1998-06-04 | Dong Kook Pharmaceutical Co., Ltd. | Medicines for treating dementia or cognitive disorder, which comprises asiatic acid derivatives |
| WO1998037899A1 (en) * | 1997-02-28 | 1998-09-03 | Dong Kook Pharmaceutical Co., Ltd. | Liver protection or treatment agents comprising asiatic acid derivatives as the active component |
| WO2002017904A1 (en) * | 2000-08-29 | 2002-03-07 | Government Of Malaysia | Use of asiatic acid or asiaticoside for treatment of cancer |
-
1960
- 1960-04-13 GB GB13220/60A patent/GB923414A/en not_active Expired
-
1961
- 1961-01-23 FR FR850453A patent/FR884M/fr active Active
- 1961-01-23 FR FR850454A patent/FR885M/fr active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4606911A (en) * | 1984-07-27 | 1986-08-19 | Rohto Pharmaceutical Co. Ltd. | Pharmaceutical composition for the prevention of dental caries |
| WO1998023278A1 (en) * | 1996-11-27 | 1998-06-04 | Dong Kook Pharmaceutical Co., Ltd. | Medicines for treating dementia or cognitive disorder, which comprises asiatic acid derivatives |
| WO1998037899A1 (en) * | 1997-02-28 | 1998-09-03 | Dong Kook Pharmaceutical Co., Ltd. | Liver protection or treatment agents comprising asiatic acid derivatives as the active component |
| WO2002017904A1 (en) * | 2000-08-29 | 2002-03-07 | Government Of Malaysia | Use of asiatic acid or asiaticoside for treatment of cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| FR884M (enrdf_load_stackoverflow) | 1961-10-23 |
| FR885M (enrdf_load_stackoverflow) | 1961-10-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101637667B (zh) | 一种三液相萃取天然产物有效成分的方法 | |
| CA1090781A (en) | Chrysanthellum plant extract | |
| AU2004216521B2 (en) | Method for the production of flavonoid-containing compositions and use thereof | |
| ES354478A1 (es) | Un procedimiento industrial de extraccion de antocianosi- dos. | |
| CN101967083A (zh) | 一种分离精制银杏浸膏中聚戊烯醇的方法 | |
| GB923414A (en) | Therapeutic compositions comprising asiatic and arjunolic acids | |
| KR20190058168A (ko) | 금목서 추출물을 포함하는 항산화 또는 항염증용 조성물 | |
| CN107929337A (zh) | 一种屏边三七抗炎有效部位的制备方法及应用 | |
| GB991663A (en) | Method for producing stable horse-chestnut seed extracts containing saponin | |
| GB934554A (en) | Methods of obtaining substantially stable concentrated extracts of red vine (vitis vinifera) and the extracts resulting therefrom | |
| CN111171106A (zh) | 一种24-羟基硬脂醇甘草亭酸酯的制备方法 | |
| CN107383129B (zh) | 一种香豆素苷类化合物及其制备方法和应用 | |
| Utrilla et al. | Isolation of a saikosaponin responsible for the antiinflammatory activity of Bupleurum gibraltaricum Lam. root extract | |
| US4132782A (en) | Method for suppressing herpes simplex virus | |
| JPS56120621A (en) | Preparation of substance having wound remedying action | |
| KR890001237B1 (ko) | 자근 색소의 추출방법 | |
| GB1177645A (en) | Plant Extracts and Compositions Containing Same. | |
| US3033877A (en) | Process of preparing same | |
| GB782469A (en) | Anti-t.b. factor | |
| PT106278B (pt) | Método para a obtenção de um extrato rico em ácidos triterpénicos a partir da casca de eucalipto | |
| GB1378278A (en) | Total saponin extracts from panax ginseng c a meyer and process for the production thereof | |
| DE2436479A1 (de) | Verfahren zur reinigung von steroidheterosiden | |
| CN104861024B (zh) | 从龙葵植株中制备β‑谷甾醇亚油酸酯的方法 | |
| US2799618A (en) | Glycosidal material having activity on the heart and vascular vessels and its preparation from plant sources | |
| JPS5444012A (en) | Preparation of purgative containing sennoside |