GB913716A - Sulphonamides - Google Patents
SulphonamidesInfo
- Publication number
- GB913716A GB913716A GB23622/61A GB2362261A GB913716A GB 913716 A GB913716 A GB 913716A GB 23622/61 A GB23622/61 A GB 23622/61A GB 2362261 A GB2362261 A GB 2362261A GB 913716 A GB913716 A GB 913716A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- pyrimidines
- guanidine
- methoxy
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises sulphonamides of the formula <FORM:0913716/IV (b)/1> wherein R is an alkyl radical of 2-5 carbon atoms and X is hydrogen, halogen e.g. Cl, or an alkyl or alkoxy e.g. methyl or methoxy, radical, and their preparation either by reacting a 2-amino-5-alkoxy-pyrimidine with the appropriate benzenesulphonyl chloride, or by condensing the reaction product of an alkoxyaldehyde acetal or a 1,2-dialkoxyethylene an N,N-disubstituted formamide and an inorganic acid chloride such as phosgene (Vilsmeier reaction) with the appropriate benzenesulphonyl - guanidine. Specified products include 2-benzenesulphonamido- and 2-p-methyl-, p-methoxy- and p-chlorobenzenesulphonamido - 5 - ethoxy-, -propoxy- and -butoxy-pyrimidines. 2-Amino-5-alkoxy-pyrimidines are made by treating an a -alkoxy-b -dimethylamino-acrolein with guanidine in the presence of an alkali-metal alcoholate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF0031592 | 1960-07-06 | ||
DEF0031983 | 1960-08-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB913716A true GB913716A (en) | 1962-12-28 |
Family
ID=25974711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB23622/61A Expired GB913716A (en) | 1960-07-06 | 1961-07-29 | Sulphonamides |
Country Status (5)
Country | Link |
---|---|
US (1) | US3207758A (en) |
CH (2) | CH431536A (en) |
DE (2) | DE1302650C2 (en) |
FR (1) | FR2757M (en) |
GB (1) | GB913716A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3331841A (en) * | 1961-02-22 | 1967-07-18 | Schering Ag | Certain derivatives of 2-amino-5-alkoxypyrimidine |
US3293259A (en) * | 1965-08-13 | 1966-12-20 | American Home Prod | Certain 1-arylsulfonyl-1, 2, 4-triazoles |
US3980781A (en) * | 1966-03-31 | 1976-09-14 | Imperial Chemical Industries Limited | Fungicidal composition and method containing 2-amino-pyrimidines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2535635A (en) * | 1948-05-06 | 1950-12-26 | American Cyanamid Co | Substituted pyrimidines and preparation of the same |
US2563725A (en) * | 1949-05-10 | 1951-08-07 | American Cyanamid Co | Phenolsulfonamides |
BE583938A (en) * | 1958-10-25 | 1959-11-14 |
-
1960
- 1960-07-06 DE DE19601302650D patent/DE1302650C2/en not_active Expired
- 1960-08-26 DE DE19601445028 patent/DE1445028B1/en active Pending
-
1961
- 1961-05-23 CH CH598661A patent/CH431536A/en unknown
- 1961-05-23 CH CH272566A patent/CH437311A/en unknown
- 1961-06-21 US US118534A patent/US3207758A/en not_active Expired - Lifetime
- 1961-07-29 GB GB23622/61A patent/GB913716A/en not_active Expired
-
1962
- 1962-12-17 FR FR918862A patent/FR2757M/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CH437311A (en) | 1967-06-15 |
DE1302650B (en) | 1973-07-12 |
CH431536A (en) | 1967-03-15 |
DE1302650C2 (en) | 1974-02-07 |
US3207758A (en) | 1965-09-21 |
DE1445028B1 (en) | 1970-03-26 |
FR2757M (en) | 1964-08-31 |
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