GB903866A - Therapeutic preparations containing 7-substituted theophylline derivatives - Google Patents

Therapeutic preparations containing 7-substituted theophylline derivatives

Info

Publication number
GB903866A
GB903866A GB1687461A GB1687461A GB903866A GB 903866 A GB903866 A GB 903866A GB 1687461 A GB1687461 A GB 1687461A GB 1687461 A GB1687461 A GB 1687461A GB 903866 A GB903866 A GB 903866A
Authority
GB
United Kingdom
Prior art keywords
theophylline
beta
substituted
component
therapeutic preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1687461A
Inventor
Don Pierre Rene Luc Giudicelli
Charles Henri Genot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DAUSSE LAB
Original Assignee
DAUSSE LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DAUSSE LAB filed Critical DAUSSE LAB
Priority to GB1687461A priority Critical patent/GB903866A/en
Publication of GB903866A publication Critical patent/GB903866A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine

Abstract

A therapeutic preparation for the treatment of asthma comprises (a) a purine component having a musculotropic action which is a water-soluble 7-substituted thiophylline derivative and (b) an adrenergic component which is the hydrochloride of 1-(3,4-dihydroxyphenyl)-2-methyl-amino-1-propanol. Specified theophylline derivatives are 7-beta-hydroxyethyl theophylline, 7-beta-gamma dihydroxypropyl theophylline and a salt of theophylline-7-ethanoic acid. The preparation may be used orally, e.g. as a tablet, parenterally, e.g. in aqueous solution, as an aerosol or as a suppository. Optional ingredients are (a) barbiturate drugs such as butobarbital and butylethyl-malonylurea, (b) antioxidant or reducing agent, e.g. sodium bisulphite or sodium formaldehyde sulphoxylate, (c) theophylline, theophylline ethylenediamine and caffeine.
GB1687461A 1961-05-09 1961-05-09 Therapeutic preparations containing 7-substituted theophylline derivatives Expired GB903866A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1687461A GB903866A (en) 1961-05-09 1961-05-09 Therapeutic preparations containing 7-substituted theophylline derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1687461A GB903866A (en) 1961-05-09 1961-05-09 Therapeutic preparations containing 7-substituted theophylline derivatives

Publications (1)

Publication Number Publication Date
GB903866A true GB903866A (en) 1962-08-22

Family

ID=10085233

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1687461A Expired GB903866A (en) 1961-05-09 1961-05-09 Therapeutic preparations containing 7-substituted theophylline derivatives

Country Status (1)

Country Link
GB (1) GB903866A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000000184A2 (en) * 1998-06-26 2000-01-06 Delack Elaine A Use of histamine h2 mimicking substances for the treatment of multiple sclerosis
WO2003057188A1 (en) * 2001-11-21 2003-07-17 Alexza Molecular Delivery Corporation Delivery of caffeine through an inhalation route
US7232830B2 (en) 1998-06-26 2007-06-19 Elaine A Delack Method for treatment of neurodegenerative diseases and effects of aging
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US7981401B2 (en) 2002-11-26 2011-07-19 Alexza Pharmaceuticals, Inc. Diuretic aerosols and methods of making and using them
US7987846B2 (en) 2002-05-13 2011-08-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US8235037B2 (en) 2001-05-24 2012-08-07 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US8333197B2 (en) 2004-06-03 2012-12-18 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US8387612B2 (en) 2003-05-21 2013-03-05 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000000184A2 (en) * 1998-06-26 2000-01-06 Delack Elaine A Use of histamine h2 mimicking substances for the treatment of multiple sclerosis
WO2000000184A3 (en) * 1998-06-26 2000-11-09 Elaine A Delack Use of histamine h2 mimicking substances for the treatment of multiple sclerosis
US7232830B2 (en) 1998-06-26 2007-06-19 Elaine A Delack Method for treatment of neurodegenerative diseases and effects of aging
US9440034B2 (en) 2001-05-24 2016-09-13 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US9211382B2 (en) 2001-05-24 2015-12-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US8235037B2 (en) 2001-05-24 2012-08-07 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US10350157B2 (en) 2001-05-24 2019-07-16 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7942147B2 (en) 2001-06-05 2011-05-17 Alexza Pharmaceuticals, Inc. Aerosol forming device for use in inhalation therapy
US9687487B2 (en) 2001-06-05 2017-06-27 Alexza Pharmaceuticals, Inc. Aerosol forming device for use in inhalation therapy
US9439907B2 (en) 2001-06-05 2016-09-13 Alexza Pharmaceutical, Inc. Method of forming an aerosol for inhalation delivery
US8074644B2 (en) 2001-06-05 2011-12-13 Alexza Pharmaceuticals, Inc. Method of forming an aerosol for inhalation delivery
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US9308208B2 (en) 2001-06-05 2016-04-12 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US8955512B2 (en) 2001-06-05 2015-02-17 Alexza Pharmaceuticals, Inc. Method of forming an aerosol for inhalation delivery
US7078016B2 (en) 2001-11-21 2006-07-18 Alexza Pharmaceuticals, Inc. Delivery of caffeine through an inhalation route
WO2003057188A1 (en) * 2001-11-21 2003-07-17 Alexza Molecular Delivery Corporation Delivery of caffeine through an inhalation route
US7987846B2 (en) 2002-05-13 2011-08-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7981401B2 (en) 2002-11-26 2011-07-19 Alexza Pharmaceuticals, Inc. Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US9370629B2 (en) 2003-05-21 2016-06-21 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same
US8387612B2 (en) 2003-05-21 2013-03-05 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same
US8991387B2 (en) 2003-05-21 2015-03-31 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same
US8333197B2 (en) 2004-06-03 2012-12-18 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols

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