GB894339A - Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide - Google Patents
Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxideInfo
- Publication number
- GB894339A GB894339A GB12089/59A GB1208959A GB894339A GB 894339 A GB894339 A GB 894339A GB 12089/59 A GB12089/59 A GB 12089/59A GB 1208959 A GB1208959 A GB 1208959A GB 894339 A GB894339 A GB 894339A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphamyl
- benzothiadiazine
- dihydro
- chloro
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A pharmaceutical preparation comprises 6-chloro - g - sulphamyl - 3,4 - dihydro - 1,2,4 - benzothiadiazine - 1,1 - dioxide (A) or a physiologically tolerable salt thereof and carboethoxy syringate of methyl reserpate (syrosingopine) (B) or a physiologically tolerable salt thereof. Salts of (A) are the alkali metal salts such as sodium and potassium. Salts of (B) are the hydrochloride and sulphate. The preparations are put up in the form of tablet, capsule or pill for oral use. The preparations contain 1 to 20 and preferably 2.0 to 10 and particularly 2.5% of (A) and 0.02 to 0.6 and preferably 0.04 to 0.3 and particularly 0.5% of (B). In oral dosage form, the units comprise 10 to 200 mg. and preferably 20 to 100 mg. and particularly 25 mg. of (A) and 0.2 to 6.0 mg. and preferably 0.4 to 3.0 mg, and especially 0.5 mg. of (B). In one example, (B) is mixed with starch, and (A) is mixed with silica, lactose, sugar and stearic acid powder, the powders are mixed and granulated with aqueous starch paste and 50% alcohol. Specifications 744,290 and 847,064 are referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US894339XA | 1958-04-09 | 1958-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB894339A true GB894339A (en) | 1962-04-18 |
Family
ID=22217617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12089/59A Expired GB894339A (en) | 1958-04-09 | 1959-04-09 | Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB894339A (en) |
-
1959
- 1959-04-09 GB GB12089/59A patent/GB894339A/en not_active Expired
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