GB879882A - Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide - Google Patents

Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide

Info

Publication number
GB879882A
GB879882A GB12091/59A GB1209159A GB879882A GB 879882 A GB879882 A GB 879882A GB 12091/59 A GB12091/59 A GB 12091/59A GB 1209159 A GB1209159 A GB 1209159A GB 879882 A GB879882 A GB 879882A
Authority
GB
United Kingdom
Prior art keywords
sulphamyl
benzothiadiazine
dihydro
chloro
dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12091/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB879882A publication Critical patent/GB879882A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutical preparation for the treatment of hypertension comprises 6-chloro-7-sulphamyl - 3 : 4 - dihydro - 1,2 : 4 - benzothiadiazine-1 : 1-dioxide (A) or a physiologically tolerable salt thereof and a 1-hydrazinophthalazine (B) or a physiologically tolerable salt thereof. Specified salts of (A) are the alkali metal salts such as sodium and potassium and salts of (B) are the sulphate, hydrochloride, hydrobromide and methane sulphonate. The compositions may be in dosage unit form for oral administration e.g. tablet, capsule or pill and contain 1 to 20, and especially 2 to 10%, of (A) and 1 to 60 and especially 2.5 to 5.0% of (B). Alternatively, the dosage unit contains 10 to 200 and especially 20 to 100 mg. particularly 25 mg. of (A) with 10 to 1000 and especially 25 to 150 mg. particularly 50 mg. of (B). The examples relate to tablets of (A) and (B) with conventional adjuvants. A core of (A) with conventional adjuvants may be coated with (B) admixed with conventional adjuvants. Specified 1-hydrazino-phthalazines are 1-hydrazinophthalazine and 1,4-dihydrazino-phthalazine. Specifications 629,177, 654,821 and 847,064 are referred to.
GB12091/59A 1958-04-09 1959-04-09 Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide Expired GB879882A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US879882XA 1958-04-09 1958-04-09

Publications (1)

Publication Number Publication Date
GB879882A true GB879882A (en) 1961-10-11

Family

ID=22208440

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12091/59A Expired GB879882A (en) 1958-04-09 1959-04-09 Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide

Country Status (1)

Country Link
GB (1) GB879882A (en)

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