GB879882A - Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide - Google Patents
Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxideInfo
- Publication number
- GB879882A GB879882A GB12091/59A GB1209159A GB879882A GB 879882 A GB879882 A GB 879882A GB 12091/59 A GB12091/59 A GB 12091/59A GB 1209159 A GB1209159 A GB 1209159A GB 879882 A GB879882 A GB 879882A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphamyl
- benzothiadiazine
- dihydro
- chloro
- dioxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A pharmaceutical preparation for the treatment of hypertension comprises 6-chloro-7-sulphamyl - 3 : 4 - dihydro - 1,2 : 4 - benzothiadiazine-1 : 1-dioxide (A) or a physiologically tolerable salt thereof and a 1-hydrazinophthalazine (B) or a physiologically tolerable salt thereof. Specified salts of (A) are the alkali metal salts such as sodium and potassium and salts of (B) are the sulphate, hydrochloride, hydrobromide and methane sulphonate. The compositions may be in dosage unit form for oral administration e.g. tablet, capsule or pill and contain 1 to 20, and especially 2 to 10%, of (A) and 1 to 60 and especially 2.5 to 5.0% of (B). Alternatively, the dosage unit contains 10 to 200 and especially 20 to 100 mg. particularly 25 mg. of (A) with 10 to 1000 and especially 25 to 150 mg. particularly 50 mg. of (B). The examples relate to tablets of (A) and (B) with conventional adjuvants. A core of (A) with conventional adjuvants may be coated with (B) admixed with conventional adjuvants. Specified 1-hydrazino-phthalazines are 1-hydrazinophthalazine and 1,4-dihydrazino-phthalazine. Specifications 629,177, 654,821 and 847,064 are referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US879882XA | 1958-04-09 | 1958-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB879882A true GB879882A (en) | 1961-10-11 |
Family
ID=22208440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12091/59A Expired GB879882A (en) | 1958-04-09 | 1959-04-09 | Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxide |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB879882A (en) |
-
1959
- 1959-04-09 GB GB12091/59A patent/GB879882A/en not_active Expired
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