GB879881A - Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide - Google Patents

Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide

Info

Publication number
GB879881A
GB879881A GB12090/59A GB1209059A GB879881A GB 879881 A GB879881 A GB 879881A GB 12090/59 A GB12090/59 A GB 12090/59A GB 1209059 A GB1209059 A GB 1209059A GB 879881 A GB879881 A GB 879881A
Authority
GB
United Kingdom
Prior art keywords
dioxide
sulphamyl
benzothiadiazine
dihydro
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12090/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB879881A publication Critical patent/GB879881A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical preparation comprises 6-chloro - 7 - sulphamyl - 3,4 - dihydro - 1,2,4-benzothiadiazine - 1,1 - dioxide (A) or a physiologically tolerable salt thereof and an indole alkaloid of the Apocyanacene family (B) or a physiologically tolerable salt thereof. Salts of (A) are the alkali metal salts such as sodium and potassium mono and polysalts. Salts of (B) are the hydrochloride and sulphate. The preparation may be put up in the form of a tablet, capsule or pill for oral use. The preparations contain 1 to 20, and preferably 2.5 to 10, and particularly 2.5% of (A), and 0.005 to 0.5, and preferably 0.01 to 0.04, and particularly 0.01% of (B). In oral dosage form, the units comprise 10 to 200 mg. and preferably 25 to 100 mg. and particularly 25 mg. of (A) and 0.05 to 5.0 mg. and preferably 0.1 to 0.4 mg. and particularly 0.1 mg. of (B). Specified alkaloids are reserpine, deserpidine and rescinnamine. In one example, (A) and (B) are mixed with silicon dioxide, magnesium stearate and starch, granulated with aqueous starch paste and sufficient 50% aqueous alcohol, and compressed into tablets. Specification 847,064 is referred to.
GB12090/59A 1958-04-09 1959-04-09 Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide Expired GB879881A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US879881XA 1958-04-09 1958-04-09

Publications (1)

Publication Number Publication Date
GB879881A true GB879881A (en) 1961-10-11

Family

ID=22208439

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12090/59A Expired GB879881A (en) 1958-04-09 1959-04-09 Pharmaceutical preparations containing 6-chloro-7-sulphamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide

Country Status (1)

Country Link
GB (1) GB879881A (en)

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