GB8908085D0 - New therapeutic use - Google Patents

New therapeutic use

Info

Publication number
GB8908085D0
GB8908085D0 GB898908085A GB8908085A GB8908085D0 GB 8908085 D0 GB8908085 D0 GB 8908085D0 GB 898908085 A GB898908085 A GB 898908085A GB 8908085 A GB8908085 A GB 8908085A GB 8908085 D0 GB8908085 D0 GB 8908085D0
Authority
GB
United Kingdom
Prior art keywords
therapeutic use
new therapeutic
dopamine neurones
neurones
imidazolidinon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB898908085A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10654774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB8908085(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to GB898908085A priority Critical patent/GB8908085D0/en
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of GB8908085D0 publication Critical patent/GB8908085D0/en
Priority to IE105190A priority patent/IE81157B1/en
Priority to AT90610022T priority patent/ATE157005T1/de
Priority to DK90610022T priority patent/DK0392959T3/da
Priority to DE1998175011 priority patent/DE19875011I2/de
Priority to SG1996008153A priority patent/SG48234A1/en
Priority to DE69031290T priority patent/DE69031290T2/de
Priority to EP90610022A priority patent/EP0392959B1/en
Priority to NZ243765A priority patent/NZ243765A/en
Priority to NZ233179A priority patent/NZ233179A/en
Priority to IL9402190A priority patent/IL94021A/en
Priority to JP2090502A priority patent/JP2775191B2/ja
Priority to CA002014208A priority patent/CA2014208C/en
Priority to AU53037/90A priority patent/AU621735B2/en
Priority to ZA902785A priority patent/ZA902785B/xx
Priority to KR1019900004984A priority patent/KR920008703B1/ko
Priority to US07/508,240 priority patent/US5112838A/en
Priority to US07/876,040 priority patent/US5238945A/en
Priority to LV960117A priority patent/LV5824B4/xx
Priority to NL980008C priority patent/NL980008I1/nl
Priority to HK98101302.4A priority patent/HK1002825B/en
Priority to CY9802082A priority patent/CY2082B1/xx
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
GB898908085A 1989-04-11 1989-04-11 New therapeutic use Pending GB8908085D0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GB898908085A GB8908085D0 (en) 1989-04-11 1989-04-11 New therapeutic use
IE105190A IE81157B1 (en) 1989-04-11 1990-03-21 Use of sertindole for the treatment of schizophrenia
EP90610022A EP0392959B1 (en) 1989-04-11 1990-03-30 Use of sertindole for the treatment of schizophrenia
DE69031290T DE69031290T2 (de) 1989-04-11 1990-03-30 Verwendung von Sertindol zur Behandlung von Schizophrenie
DK90610022T DK0392959T3 (da) 1989-04-11 1990-03-30 Anvendelse af Sertindole til behandling af skizofreni
AT90610022T ATE157005T1 (de) 1989-04-11 1990-03-30 Verwendung von sertindol zur behandlung von schizophrenie
DE1998175011 DE19875011I2 (de) 1989-04-11 1990-03-30 Verwendung von Sertindol zur Behandlung von Schiz ophrenie.
SG1996008153A SG48234A1 (en) 1989-04-11 1990-03-30 Use of sertindole for the treatment of schizophrenia
NZ243765A NZ243765A (en) 1989-04-11 1990-04-03 Use of 5-chloro-1-(4-fluorophenyl)-3-(1-(2-(2-imidazolidinon-1-yl)ethyl)-4-piper idyl)-1h-indole to prepare medicaments for blocking dopamine neurones in the brain
NZ233179A NZ233179A (en) 1989-04-11 1990-04-03 Selectively blocking dopamine neurones using 5-chloro-1-(4-fluorophenyl) -3-(2(2-imidazolinon-1-yl)ethyl-4-piperidyl)-1-h-indole (lu 23-174)
IL9402190A IL94021A (en) 1989-04-11 1990-04-05 Atypical neuroleptic composition comprising 5-chloro-1- (4-fluorophenyl) -3-(1-(2-(2-imidazolidinon-1-yl) ethyl)-4-piperidyl) -1h-indole
JP2090502A JP2775191B2 (ja) 1989-04-11 1990-04-06 ５―クロロ―１―（４―フルオロフェニル） ―３―（１―（２― （２―イミダゾリジノン―１―イル）エチル） ―４―ピペリジル）―１ｈ―インドールまたはその薬学的に容認できる酸付加塩を使用する方法
CA002014208A CA2014208C (en) 1989-04-11 1990-04-09 Selective blocking of spontaneously-active dopamine neurones in ventral tegmental area
AU53037/90A AU621735B2 (en) 1989-04-11 1990-04-10 Method of treating menial disorders
ZA902785A ZA902785B (en) 1989-04-11 1990-04-11 Method of treating mental disorders
KR1019900004984A KR920008703B1 (ko) 1989-04-11 1990-04-11 사람의 정신질환 치료용 제약학적 조성물
US07/508,240 US5112838A (en) 1989-04-11 1990-04-11 Method of treating psychoses in human beings with the atypical neuroleptic 5-chloro-1-(4-fluorophenyl)-3-(1-(2-(2-imidazolidinon-1-yl)ethyl-4-piperidyl)1h-indole
US07/876,040 US5238945A (en) 1989-04-11 1992-04-30 Method of treating psychoses
LV960117A LV5824B4 (lv) 1989-04-11 1996-04-16 Cilveku psihozes arstesanas panemiens
NL980008C NL980008I1 (nl) 1989-04-11 1998-02-18 Gebruik van sertindool voor de behandeling van schizofrenie.
HK98101302.4A HK1002825B (en) 1989-04-11 1998-02-19 Use of sertindole for the treatment of schizophrenia
CY9802082A CY2082B1 (en) 1989-04-11 1998-10-16 Use of sertindole for the treatment of schizophrenia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898908085A GB8908085D0 (en) 1989-04-11 1989-04-11 New therapeutic use

Publications (1)

Publication Number Publication Date
GB8908085D0 true GB8908085D0 (en) 1989-05-24

Family

ID=10654774

Family Applications (1)

Application Number Title Priority Date Filing Date
GB898908085A Pending GB8908085D0 (en) 1989-04-11 1989-04-11 New therapeutic use

Country Status (17)

Country Link
US (1) US5112838A (enExample)
EP (1) EP0392959B1 (enExample)
JP (1) JP2775191B2 (enExample)
KR (1) KR920008703B1 (enExample)
AT (1) ATE157005T1 (enExample)
AU (1) AU621735B2 (enExample)
CA (1) CA2014208C (enExample)
CY (1) CY2082B1 (enExample)
DE (2) DE19875011I2 (enExample)
DK (1) DK0392959T3 (enExample)
GB (1) GB8908085D0 (enExample)
IE (1) IE81157B1 (enExample)
IL (1) IL94021A (enExample)
NL (1) NL980008I1 (enExample)
NZ (2) NZ243765A (enExample)
SG (1) SG48234A1 (enExample)
ZA (1) ZA902785B (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238945A (en) * 1989-04-11 1993-08-24 H. Lundbeck A/S Method of treating psychoses
DK238190D0 (da) * 1990-10-03 1990-10-03 Lundbeck & Co As H Depotderivater
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK206591D0 (da) * 1991-12-23 1991-12-23 Lundbeck & Co As H Behandling af psykoser
DK8492D0 (da) * 1992-01-23 1992-01-23 Lundbeck & Co As H Behandling af psykoser
DK123493D0 (da) * 1993-11-01 1993-11-01 Lundbeck & Co As H Compounds
EP0906104A4 (en) * 1996-03-25 2003-12-10 Lilly Co Eli PAIN TREATMENT PROCESS
ZA973433B (en) * 1996-04-24 1997-12-10 Shionogi & Co A sertindole-containing preparation and a method for producing the same.
DK1026950T3 (da) * 1997-10-27 2006-06-26 Univ California Behandling af skizofreni med ampakiner og neuroleptika
GB9805716D0 (en) * 1998-03-17 1998-05-13 Merck Sharp & Dohme Therapeutic agents
US6489341B1 (en) 1999-06-02 2002-12-03 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
US20040023951A1 (en) * 2001-06-18 2004-02-05 Bymaster Franklin Porter Combination therapy for treatment of psychoses
DE60239634D1 (de) * 2001-12-10 2011-05-12 Novartis Ag Verfahren zur behandlung von psychosen und schizophrenie auf der basis eines polymorphismus im cntf gen
MXPA04009365A (es) * 2002-03-27 2005-01-25 Lundbeck & Co As H Metodo para la manufactura de sertindol.
CA2525366A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
GB0326148D0 (en) 2003-11-10 2003-12-17 Lilly Co Eli Morpholine derivatives
EP1737473A4 (en) * 2004-04-19 2009-08-26 Noven Therapeutics Llc COMBINATIONS OF LITHIUM AND USES THEREOF
MXPA06013163A (es) * 2004-05-11 2007-02-13 Pfizer Prod Inc Combinacion de antipsicoticos atipicos y antagonistas del receptor 5-ht1b.
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
AR049646A1 (es) * 2004-06-16 2006-08-23 Janssen Pharmaceutica Nv Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados
TW200616608A (en) * 2004-07-09 2006-06-01 Forest Laboratories Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients
DE602005008084D1 (de) * 2004-08-24 2008-08-21 Janssen Pharmaceutica Nv Als antikonvulsive mittel geeignete neue benzokondensierte heteroarylsulfamidderivate
KR20080012360A (ko) * 2005-05-20 2008-02-11 얀센 파마슈티카 엔.브이. 설파미드 유도체의 제조 방법
US20070212412A1 (en) * 2005-09-08 2007-09-13 H. Lundbeck A/S Stable solid formulation of sertindole
US20070155824A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis
US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
US8497298B2 (en) * 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US20070155823A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents
US8492431B2 (en) * 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8691867B2 (en) * 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US20070191474A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine
US20070191450A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Mania and Bipolar Disorder
US20070191451A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives as neuroprotective agents
US20070191460A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Disease Modification / Epileptogenesis
EA200870556A1 (ru) * 2006-05-19 2009-06-30 Янссен Фармацевтика Н.В. Комбинированная терапия в лечении эпилепсии и родственных расстройств
TW200821296A (en) * 2006-06-01 2008-05-16 Lundbeck & Co As H Use of sertindole for the preventive treatment of suicidal behaviour
EP2041304B1 (en) * 2006-06-12 2011-09-07 Hadasit Medical Research Services & Development Limited Rgs2 genotypes associated with extrapyramidal symptoms induced by antipsychotic medication
PL2083811T3 (pl) 2006-11-22 2017-05-31 Clinical Research Associates, Llc Sposoby leczenia zespołu downa, zespołu łamliwego chromosomu x oraz autyzmu
WO2008106144A2 (en) * 2007-02-28 2008-09-04 Nupathe Inc. Implants for the treatment of psychiatric states
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
EP2288345B1 (en) 2008-04-18 2015-06-10 University College Dublin National University Of Ireland, Dublin Psycho-pharmaceuticals
EA018567B1 (ru) 2008-06-23 2013-08-30 Янссен Фармацевтика Нв Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида
CA2727573A1 (en) * 2008-06-25 2009-12-30 Pfizer Inc. Diaryl compounds and uses thereof
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
US8252801B1 (en) 2009-06-03 2012-08-28 Abbott Laboratories Treatment of schizophrenia and related disorders
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
ZA891901B (en) * 1988-03-17 1989-11-29 Merrell Dow Pharma Method for the treatment of the extrapyramidal side effects associated with neuroleptic therapy

Also Published As

Publication number Publication date
EP0392959A3 (en) 1992-05-06
IE901051L (en) 1990-10-11
IE81157B1 (en) 2000-05-03
AU621735B2 (en) 1992-03-19
NZ243765A (en) 1997-09-22
JP2775191B2 (ja) 1998-07-16
US5112838A (en) 1992-05-12
DK0392959T3 (da) 1999-03-29
AU5303790A (en) 1990-10-18
EP0392959B1 (en) 1997-08-20
CA2014208C (en) 1996-03-19
KR900015730A (ko) 1990-11-10
ZA902785B (en) 1991-06-26
DE69031290D1 (de) 1997-09-25
CY2082B1 (en) 1998-10-16
IL94021A (en) 1994-01-25
CA2014208A1 (en) 1990-10-11
JPH02290872A (ja) 1990-11-30
NL980008I1 (nl) 1998-05-06
DE19875011I2 (de) 2004-07-01
DE69031290T2 (de) 1998-01-02
NZ233179A (en) 1996-12-20
IL94021A0 (enExample) 1991-01-31
HK1002825A1 (en) 1998-09-18
KR920008703B1 (ko) 1992-10-08
EP0392959A2 (en) 1990-10-17
ATE157005T1 (de) 1997-09-15
SG48234A1 (en) 1998-04-17

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