GB888968A - Improvements in or relating to tetracycline derivatives - Google Patents
Improvements in or relating to tetracycline derivativesInfo
- Publication number
- GB888968A GB888968A GB10886/59A GB1088659A GB888968A GB 888968 A GB888968 A GB 888968A GB 10886/59 A GB10886/59 A GB 10886/59A GB 1088659 A GB1088659 A GB 1088659A GB 888968 A GB888968 A GB 888968A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetracycline
- betahydroxyethyl
- diamino
- diethylene
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004098 Tetracycline Substances 0.000 title abstract 4
- 229960002180 tetracycline Drugs 0.000 title abstract 4
- 229930101283 tetracycline Natural products 0.000 title abstract 4
- 235000019364 tetracycline Nutrition 0.000 title abstract 4
- 150000003522 tetracyclines Chemical class 0.000 title abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- NWXMGUDVXFXRIG-WESIUVDSSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O NWXMGUDVXFXRIG-WESIUVDSSA-N 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- LHIJANUOQQMGNT-UHFFFAOYSA-N aminoethylethanolamine Chemical compound NCCNCCO LHIJANUOQQMGNT-UHFFFAOYSA-N 0.000 abstract 1
- -1 betahydroxyethyl Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- JMMWKPVZQRWMSS-UHFFFAOYSA-N isopropanol acetate Natural products CC(C)OC(C)=O JMMWKPVZQRWMSS-UHFFFAOYSA-N 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G11/00—Antibiotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB10886/59A GB888968A (en) | 1959-03-31 | 1959-03-31 | Improvements in or relating to tetracycline derivatives |
| FR1584701D FR1584701A (en)) | 1959-03-31 | 1960-03-15 | |
| BE588705A BE588705A (fr) | 1959-03-31 | 1960-03-16 | Dérivé nouveau de la tétracycline et son procédé de fabrication |
| CH301260A CH394214A (fr) | 1959-03-31 | 1960-03-17 | Procédé de fabrication d'un dérivé nouveau de la tétracycline |
| BR118004/60A BR6018004D0 (pt) | 1959-03-31 | 1960-03-23 | Processo de fabricacao da n2 (ou 9,ou7) -4 (beta hidroxietil) dietilenodiamino-metil tetraciclina |
| DE1960S0067726 DE1129494C2 (de) | 1959-03-31 | 1960-03-24 | Verfahren zur herstellung eines wasserloeslichen aminomethyltetracyclinderivats |
| FR835978A FR520M (en)) | 1959-03-31 | 1960-08-17 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB10886/59A GB888968A (en) | 1959-03-31 | 1959-03-31 | Improvements in or relating to tetracycline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB888968A true GB888968A (en) | 1962-02-07 |
Family
ID=9976122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB10886/59A Expired GB888968A (en) | 1959-03-31 | 1959-03-31 | Improvements in or relating to tetracycline derivatives |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE588705A (en)) |
| BR (1) | BR6018004D0 (en)) |
| CH (1) | CH394214A (en)) |
| FR (2) | FR1584701A (en)) |
| GB (1) | GB888968A (en)) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1196648B (de) * | 1961-03-27 | 1965-07-15 | Leo Ind Chim Farm Spa | Verfahren zur Herstellung wasserloeslicher Derivate von Tetracyclinen |
-
1959
- 1959-03-31 GB GB10886/59A patent/GB888968A/en not_active Expired
-
1960
- 1960-03-15 FR FR1584701D patent/FR1584701A/fr not_active Expired
- 1960-03-16 BE BE588705A patent/BE588705A/fr unknown
- 1960-03-17 CH CH301260A patent/CH394214A/fr unknown
- 1960-03-23 BR BR118004/60A patent/BR6018004D0/pt unknown
- 1960-08-17 FR FR835978A patent/FR520M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BE588705A (fr) | 1960-07-18 |
| BR6018004D0 (pt) | 1973-05-24 |
| CH394214A (fr) | 1965-06-30 |
| FR1584701A (en)) | 1970-01-02 |
| FR520M (en)) | 1961-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES316768A1 (es) | Procedimiento para la preparacion de una nueva poliamida. | |
| GB859510A (en) | Stabilized acrylonitrile polymers | |
| GB1386150A (en) | 6-acylaminophenyl-4,5-dihydropyridazones | |
| GB888968A (en) | Improvements in or relating to tetracycline derivatives | |
| SE7512538L (sv) | Hydrering av ftalonitriler | |
| ES400452A1 (es) | Procedimiento para la obtencion de un medio para regular el crecimiento de las plantas a base de acidos 2-halogenoe- tano sulfinicos. | |
| ES403486A1 (es) | Procedimiento para la preparacion de derivados de piperazi-na. | |
| GB974718A (en) | Maleimide derivative | |
| GB980778A (en) | Process for the production of methyl-(hydroxymethyl)-siloxanes | |
| GB980277A (en) | Improvements in or relating to preparation of cyclic amines | |
| ES256969A1 (es) | Procedimiento para la obtenciën de fenoximetilpenicilinato de n2 (09 ,07)-4-(beta-hidroxietil) - dietilendiamino - metiltetracilina, de acciën antibiëtica | |
| GB674807A (en) | Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof | |
| GB1126994A (en) | Guanidine derivatives and processes for preparing the same | |
| GB986644A (en) | Novel derivatives of salicylic acid and preparations thereof | |
| GB1058917A (en) | Monohydrate of the equimolecular complex of ascorbic acid and pyridoxine base, and process for its preparation | |
| GB681904A (en) | Solutions of thiosemicarbazones | |
| GB989332A (en) | Process for the preparation of n-(5-nitrofurfurylidene)-aminohydantoin | |
| GB995482A (en) | Process for the production of aliphatic diamines | |
| GB578251A (en) | Derivatives of pantothenic acid | |
| ES274978A1 (es) | Un procedimiento para la n-alcohilaciën de acil-anilidas halogenadas en el nucleo | |
| GB794965A (en) | Process for the preparation of indole and homologues thereof | |
| GB817777A (en) | Nitropropanediol dicarbamates | |
| GB897826A (en) | Improvements in or relating to tetracycline derivatives | |
| GB731956A (en) | New pyrimidine compounds | |
| GB973913A (en) | Derivatives of 8-azaoestrane and 8-aza-d-homooestrane |