GB888180A - - Google Patents
Info
- Publication number
- GB888180A GB888180A GB888180DA GB888180A GB 888180 A GB888180 A GB 888180A GB 888180D A GB888180D A GB 888180DA GB 888180 A GB888180 A GB 888180A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oil
- water
- type
- vaccines
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000839 emulsion Substances 0.000 abstract 6
- 235000019198 oils Nutrition 0.000 abstract 6
- 239000003921 oil Substances 0.000 abstract 5
- 229960005486 vaccine Drugs 0.000 abstract 5
- 230000000890 antigenic effect Effects 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- 239000000080 wetting agent Substances 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 2
- 241000607142 Salmonella Species 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- -1 fatty acid esters Chemical class 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 150000005846 sugar alcohols Polymers 0.000 abstract 2
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 abstract 1
- WGKYSFRFMQHMOF-UHFFFAOYSA-N 3-bromo-5-methylpyridine-2-carbonitrile Chemical compound CC1=CN=C(C#N)C(Br)=C1 WGKYSFRFMQHMOF-UHFFFAOYSA-N 0.000 abstract 1
- 235000003911 Arachis Nutrition 0.000 abstract 1
- 244000105624 Arachis hypogaea Species 0.000 abstract 1
- 241000589562 Brucella Species 0.000 abstract 1
- 206010008631 Cholera Diseases 0.000 abstract 1
- 241000710777 Classical swine fever virus Species 0.000 abstract 1
- 241001112695 Clostridiales Species 0.000 abstract 1
- PYGXAGIECVVIOZ-UHFFFAOYSA-N Dibutyl decanedioate Chemical compound CCCCOC(=O)CCCCCCCCC(=O)OCCCC PYGXAGIECVVIOZ-UHFFFAOYSA-N 0.000 abstract 1
- LVGKNOAMLMIIKO-UHFFFAOYSA-N Elaidinsaeure-aethylester Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC LVGKNOAMLMIIKO-UHFFFAOYSA-N 0.000 abstract 1
- 241000186810 Erysipelothrix rhusiopathiae Species 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- PMGCQNGBLMMXEW-UHFFFAOYSA-N Isoamyl salicylate Chemical compound CC(C)CCOC(=O)C1=CC=CC=C1O PMGCQNGBLMMXEW-UHFFFAOYSA-N 0.000 abstract 1
- 241001215120 Leptospirales Species 0.000 abstract 1
- 241000710769 Louping ill virus Species 0.000 abstract 1
- 240000007817 Olea europaea Species 0.000 abstract 1
- 208000000474 Poliomyelitis Diseases 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 235000003434 Sesamum indicum Nutrition 0.000 abstract 1
- 244000000231 Sesamum indicum Species 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 208000003217 Tetany Diseases 0.000 abstract 1
- 206010044302 Tracheitis Diseases 0.000 abstract 1
- BJXXCOMGRRCAGN-XPWSMXQVSA-N [2,2-bis(hydroxymethyl)-3-[(e)-octadec-9-enoyl]oxypropyl] (e)-octadec-9-enoate Chemical compound CCCCCCCC\C=C\CCCCCCCC(=O)OCC(CO)(CO)COC(=O)CCCCCCC\C=C\CCCCCCCC BJXXCOMGRRCAGN-XPWSMXQVSA-N 0.000 abstract 1
- 206010000210 abortion Diseases 0.000 abstract 1
- 231100000176 abortion Toxicity 0.000 abstract 1
- 239000002156 adsorbate Substances 0.000 abstract 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 abstract 1
- 229940001007 aluminium phosphate Drugs 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- CEGOLXSVJUTHNZ-UHFFFAOYSA-K aluminium tristearate Chemical compound [Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CEGOLXSVJUTHNZ-UHFFFAOYSA-K 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 229960001212 bacterial vaccine Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- ZCZLQYAECBEUBH-UHFFFAOYSA-L calcium;octadec-9-enoate Chemical compound [Ca+2].CCCCCCCCC=CCCCCCCCC([O-])=O.CCCCCCCCC=CCCCCCCCC([O-])=O ZCZLQYAECBEUBH-UHFFFAOYSA-L 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012343 cottonseed oil Nutrition 0.000 abstract 1
- 239000002385 cottonseed oil Substances 0.000 abstract 1
- 206010013023 diphtheria Diseases 0.000 abstract 1
- LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 abstract 1
- 229940093471 ethyl oleate Drugs 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 150000002191 fatty alcohols Chemical class 0.000 abstract 1
- 239000003349 gelling agent Substances 0.000 abstract 1
- 238000000265 homogenisation Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940057995 liquid paraffin Drugs 0.000 abstract 1
- 150000004668 long chain fatty acids Chemical class 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 229920000847 nonoxynol Polymers 0.000 abstract 1
- 239000008041 oiling agent Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 abstract 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000008262 pumice Substances 0.000 abstract 1
- 239000000344 soap Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229960005078 sorbitan sesquioleate Drugs 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- 229960004854 viral vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB888180A true GB888180A (enrdf_load_stackoverflow) | 1900-01-01 |
Family
ID=1753037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB888180D Expired GB888180A (enrdf_load_stackoverflow) |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB888180A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149036A (en) * | 1961-10-16 | 1964-09-15 | Merck & Co Inc | Adjuvant vaccine with aluminum monostearate, mannide monooleate, vegetable oil, and an aqueous phase immunolgical agent |
| EP0129923A1 (en) * | 1983-06-06 | 1985-01-02 | Duphar International Research B.V | Method of preparing adjuvanted live vaccines and adjuvanted live vaccines thus obtained |
| EP0108316A3 (de) * | 1982-11-06 | 1986-10-08 | Bayer Ag | Vakzinen mit Zuschlagstoffen |
| EP0399843A3 (en) * | 1989-05-25 | 1992-09-02 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| GB2544395A (en) * | 2015-09-25 | 2017-05-17 | Mitsubishi Materials Corp | Precious metal clay regeneration solution and method for regenerating precious metal clay |
-
0
- GB GB888180D patent/GB888180A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149036A (en) * | 1961-10-16 | 1964-09-15 | Merck & Co Inc | Adjuvant vaccine with aluminum monostearate, mannide monooleate, vegetable oil, and an aqueous phase immunolgical agent |
| EP0108316A3 (de) * | 1982-11-06 | 1986-10-08 | Bayer Ag | Vakzinen mit Zuschlagstoffen |
| US4698221A (en) * | 1982-11-06 | 1987-10-06 | Bayer Aktiengesellschaft | Vaccines containing fat soluble vitamins, zinc compounds and selenium compounds |
| EP0129923A1 (en) * | 1983-06-06 | 1985-01-02 | Duphar International Research B.V | Method of preparing adjuvanted live vaccines and adjuvanted live vaccines thus obtained |
| EP0399843A3 (en) * | 1989-05-25 | 1992-09-02 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| GB2544395A (en) * | 2015-09-25 | 2017-05-17 | Mitsubishi Materials Corp | Precious metal clay regeneration solution and method for regenerating precious metal clay |
| US9868669B2 (en) | 2015-09-25 | 2018-01-16 | Mitsubishi Materials Corporation | Precious metal clay regeneration solution and method for regenerating precious metal clay |
| GB2544395B (en) * | 2015-09-25 | 2019-05-22 | Mitsubishi Materials Corp | Method for regenerating precious metal clay |
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