GB875948A - Quinone derivatives - Google Patents

Quinone derivatives

Info

Publication number
GB875948A
GB875948A GB41931/59A GB4193159A GB875948A GB 875948 A GB875948 A GB 875948A GB 41931/59 A GB41931/59 A GB 41931/59A GB 4193159 A GB4193159 A GB 4193159A GB 875948 A GB875948 A GB 875948A
Authority
GB
United Kingdom
Prior art keywords
acid
monoguanylhydrazone
benzoquinone
reacting
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB41931/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB875948A publication Critical patent/GB875948A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises the compound of the formula <FORM:0875948/IV (b)/1> and its acid addition salts, and pharmaceutical preparations containing them (see Group VI), and the preparation of the compounds by reacting p-benzoquinone monoguanylhydrazone monothiosemicarbazone with chloracetic or bromacetic acid or a salt or the methyl or ethyl ester thereof, or by reacting p-benzoquinone monoguanylhydrazone with 4-hydroxythiazolyl-(2)-hydrazine or its N-isopropylidene derivative. Both reactions are advantageously effected in the presence of an aqueous mineral acid to give the product in the form of an addition salt with the acid.ALSO:Pharmaceutical preparations having bacteriostatic or bactericidal activity comprise the compound of the formula <FORM:0875948/VI/1> or the hydrate or an acid addition salt (e.g. the nitrate) thereof, and an organic or inorganic solid or liquid vehicle. They may be in tablet, spray or powder form and may contain other pharmaceutical agents, e.g. sulphadiazin.
GB41931/59A 1958-12-11 1959-12-09 Quinone derivatives Expired GB875948A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE875948X 1958-12-11

Publications (1)

Publication Number Publication Date
GB875948A true GB875948A (en) 1961-08-23

Family

ID=6817494

Family Applications (1)

Application Number Title Priority Date Filing Date
GB41931/59A Expired GB875948A (en) 1958-12-11 1959-12-09 Quinone derivatives

Country Status (1)

Country Link
GB (1) GB875948A (en)

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