GB875023A - New succinimides and process for their manufacture - Google Patents

New succinimides and process for their manufacture

Info

Publication number
GB875023A
GB875023A GB36105/58A GB3610558A GB875023A GB 875023 A GB875023 A GB 875023A GB 36105/58 A GB36105/58 A GB 36105/58A GB 3610558 A GB3610558 A GB 3610558A GB 875023 A GB875023 A GB 875023A
Authority
GB
United Kingdom
Prior art keywords
amino group
acylated
acid addition
compound
succinimide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB36105/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB875023A publication Critical patent/GB875023A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

The invention comprises the compound of the formula <FORM:0875023/IV (b)/1> and acid addition salts and derivatives acylated at the amino group by a fatty acid having 1-5 carbon atoms, and pharmaceutical preparations (see Group VI) containing these compounds. The basic compound is obtained by converting into an amino group the substituent X in a compound of the formula <FORM:0875023/IV (b)/2> in which X represents a substituent convertible into an amino group, and if desired the free base may be converted into an acid addition salt or it may be acylated. The compounds have an anticonvulsive action. a -(p-Nitrophenyl)-a -ethyl-succinimide is prepared by appropriate nitration.ALSO:Pharmaceutical compositions comprise a -(p-aminophenyl) - a - ethyl - succinimide or an acid addition salt thereof or a derivative acylated at the amino group by a fatty acid having 1-5 carbon atoms in admixture with a pharmaceutical carrier. They may be in the form of tablets, dragees, solutions, suspensions or emulsions.
GB36105/58A 1957-11-08 1958-11-10 New succinimides and process for their manufacture Expired GB875023A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH875023X 1957-11-08

Publications (1)

Publication Number Publication Date
GB875023A true GB875023A (en) 1961-08-16

Family

ID=4544326

Family Applications (1)

Application Number Title Priority Date Filing Date
GB36105/58A Expired GB875023A (en) 1957-11-08 1958-11-10 New succinimides and process for their manufacture

Country Status (1)

Country Link
GB (1) GB875023A (en)

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