GB873533A - Antibacterial agents - Google Patents

Antibacterial agents

Info

Publication number
GB873533A
GB873533A GB8711/60A GB871160A GB873533A GB 873533 A GB873533 A GB 873533A GB 8711/60 A GB8711/60 A GB 8711/60A GB 871160 A GB871160 A GB 871160A GB 873533 A GB873533 A GB 873533A
Authority
GB
United Kingdom
Prior art keywords
reagent
phenyl
salt
general formula
penicillanic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8711/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Research Laboratories Ltd
Original Assignee
Beecham Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Research Laboratories Ltd filed Critical Beecham Research Laboratories Ltd
Publication of GB873533A publication Critical patent/GB873533A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Relates to compounds of the general formula: <FORM:0873533/IV (b)/1> wherein X is an oxygen or sulphur atom and R is a substituted or unsubstituted alkyl, cycloalkyl, aryl or aralkyl group and nontoxic salts thereof, and to their preparation by reacting 6-amino-penicillanic acid or an easily hydrolysed ester, an alkali or alkaline earth metal salt or tertiary amine salt thereof with a reagent of the general formula R-N =C=X wherein X and R are as above. The Specification refers to many compounds of the above formula, typical examples being 6-phenylureido-, 6-(3-chlorophenylureido)-, 6-(2-methoxyphenylureido)-, 6-cyclohexylureido-and 6-n-propylureido penicillanic acid, prepared by use as reagent of phenyl, m-chloro-phenyl, o-methoxyphenyl, cyclohexyl and n-propyl isocyanate respectively, and to salt thereof, particularly the triethylammonium and potassium salts.
GB8711/60A 1959-03-23 1960-03-11 Antibacterial agents Expired GB873533A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US873533XA 1959-03-23 1959-03-23

Publications (1)

Publication Number Publication Date
GB873533A true GB873533A (en) 1961-07-26

Family

ID=22204681

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8711/60A Expired GB873533A (en) 1959-03-23 1960-03-11 Antibacterial agents

Country Status (1)

Country Link
GB (1) GB873533A (en)

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