GB919124A - Piperidine derivatives - Google Patents

Piperidine derivatives

Info

Publication number
GB919124A
GB919124A GB668358A GB668358A GB919124A GB 919124 A GB919124 A GB 919124A GB 668358 A GB668358 A GB 668358A GB 668358 A GB668358 A GB 668358A GB 919124 A GB919124 A GB 919124A
Authority
GB
United Kingdom
Prior art keywords
morpholinoalkylamine
morpholinoalkyl
reacting
give
piperidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB668358A
Inventor
Geoffrey George Coker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB668358A priority Critical patent/GB919124A/en
Publication of GB919124A publication Critical patent/GB919124A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises compounds of the general formula: <FORM:0919124/IV (b)/1> wherein R1 is a C1-4-alkyl group and X is a straight or branched C1-4-hydrocarbon chain and their acid addition salts. The compounds are prepared by reacting a morpholinoalkylamine with ethyl acrylate to give N,N-di(2 - ethoxycarbonylethyl)-N-morpholinoalkylamine, cyclizing this with sodium ethoxide to the 1-morpholinoalkyl-4-piperidone, reacting the ketone with phenyl lithium to give the 4-hydroxy - 1-morpholinoalkyl-4-phenylpiperidine and acylating the free hydroxy group.
GB668358A 1958-03-03 1958-03-03 Piperidine derivatives Expired GB919124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB668358A GB919124A (en) 1958-03-03 1958-03-03 Piperidine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB668358A GB919124A (en) 1958-03-03 1958-03-03 Piperidine derivatives

Publications (1)

Publication Number Publication Date
GB919124A true GB919124A (en) 1963-02-20

Family

ID=9818904

Family Applications (1)

Application Number Title Priority Date Filing Date
GB668358A Expired GB919124A (en) 1958-03-03 1958-03-03 Piperidine derivatives

Country Status (1)

Country Link
GB (1) GB919124A (en)

Similar Documents

Publication Publication Date Title
GB1040545A (en) Improvements in or relating to therapeutic compounds and the manufacture thereof
GB1111989A (en) 2&#39;,3&#39;-dideoxyriboside-2&#39;,3&#39;-olefins
ES270293A1 (en) A procedure to produce dihydroantracen compounds (Machine-translation by Google Translate, not legally binding)
ES480721A1 (en) Lithium pseudomonate, process for its isolation and its hydrolysis.
ES482675A1 (en) New intermediates and their use for the preparation of new oxadiazolo-pyrimidine derivatives.
GB1213172A (en) Dibenzothiazepine derivatives and production of the same
GB919124A (en) Piperidine derivatives
GB1077936A (en) Substituted benzanilides
GB1347598A (en) Lincomycin derivatives and the manufacture thereof
GB918169A (en) New 6-amino-penicillanic acid derivatives
GB986579A (en) 5-ethylidene dibenzocycloheptadienes and the preparation thereof
GB1057697A (en) Penicillins
GB876508A (en) Improvements in or relating to substances having antibiotic activity
GB937378A (en) Production of phenylethylbenzoic acid compounds
GB1088880A (en) ª‡-cycloalkyleneimino-substituted esters
GB1085075A (en) 8-aza-steroid derivatives
GB1100959A (en) Anthranilic acid derivatives
GB1131022A (en) Herbicidal compositions and the manufacture thereof
GB878603A (en) Salicyclic acid derivatives
GB943608A (en) Penicillins
GB983599A (en) Substituted 4-phenylamino-7-chloroquinolines
GB1103155A (en) Improvements in and relating to quinazolines
GB1024904A (en) Novel psychotrine derivatives
GB1024385A (en) Khellin derivatives
GB1057336A (en) Novel 3-substituted-androst-11-ones and processes for their preparation