GB863765A - Preparation of l-threonine - Google Patents

Preparation of l-threonine

Info

Publication number
GB863765A
GB863765A GB7496/59A GB749659A GB863765A GB 863765 A GB863765 A GB 863765A GB 7496/59 A GB7496/59 A GB 7496/59A GB 749659 A GB749659 A GB 749659A GB 863765 A GB863765 A GB 863765A
Authority
GB
United Kingdom
Prior art keywords
nutrient medium
coli
per litre
threonine
diaminopimelic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7496/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB863765A publication Critical patent/GB863765A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L-Threonine is prepared by cultivating Escherichia coli A.T.C.C. 13070 or 13071 under submerged aerobic conditions at temperatures between 20 and 40 DEG C. and at a pH of between 6 and 8 in an aqueous nutrient medium comprising sorbitol or mannitol, sources of nitrogen, magnesium, potassium and trace metals together with from 100 to 140 mg. of diaminopimelic acid per litre of nutrient medium when E. coli A.T.C.C. 13071 is used, or with from 100 to 250 m. of diaminopimelic acid and up to 100 mg. of L-methionine per litre of nutrient medium when E. coli A.T.C.C. 13070 is used. Yields are improved by the addition of Llycine, sucrose, cornsteep liquor and/or crude beet molasses to the nutrient medium. The product is purified by ion exchange techniques, small amounts of glycine, serine and glutamic acid being separated as by-products. Specification 610,527 is referred to.
GB7496/59A 1958-03-10 1959-03-04 Preparation of l-threonine Expired GB863765A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US863765XA 1958-03-10 1958-03-10

Publications (1)

Publication Number Publication Date
GB863765A true GB863765A (en) 1961-03-29

Family

ID=22198161

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7496/59A Expired GB863765A (en) 1958-03-10 1959-03-04 Preparation of l-threonine

Country Status (1)

Country Link
GB (1) GB863765A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1806386B1 (en) * 1968-08-17 1970-07-23 Kyowa Hakko Kogyo Kk Process for the production of L-threonine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1806386B1 (en) * 1968-08-17 1970-07-23 Kyowa Hakko Kogyo Kk Process for the production of L-threonine

Similar Documents

Publication Publication Date Title
GB1097908A (en) A fermentation process for the production of l-threonine
GB863765A (en) Preparation of l-threonine
GB1178011A (en) A method of Recovering Lysine from Fermentation Broth
US3622453A (en) Process for producing l-threonine
GB1118719A (en) Process for producing l-lysine by fermentation
GB1379268A (en) Process for production of beta-alanine
GB1380936A (en) Fermentative preparation of l-arginine
GB1049434A (en) Oxytetracycline
GB820422A (en) Production of cephalosporin by fermentation
US3684654A (en) Process for producing l-threonine
JPS5272886A (en) Preparation of cephalosporin compound
GB1029978A (en) Improvements in or relating to the production of proteolytic enzymes
GB1147229A (en) Process for producing l-lysine from 5-(4-aminobutyl)-hydantoin
GB1100807A (en) 6-amino-penicillanic acid and a process for the preparation thereof
GB1443097A (en) L-asparate of cyclic erythromycin a 6,9-hemiacetal carbonate and process of preparing the same
GB1176741A (en) Process for Producing Xanthylic Acid.
ES250488A1 (en) A procedure to produce l-glutamic acid (Machine-translation by Google Translate, not legally binding)
GB1186988A (en) Process for producing L-Lysine
GB1076052A (en) Fermentative method for the production of l-glutamic acid
GB1118942A (en) A process for obtaining purified glutamic acid
GB962684A (en) Fermentation process for preparing l-glutamic acid
GB1181592A (en) Process for Producing L-Threonine by Fermentation.
GB1391088A (en) Production of d-alpha-amino-1,4-cyclohexadienyl methyl penicillin
GB853563A (en) Lysine racemase and the preparation of dl-lysine
GB955087A (en) Magnesium glutamate hydrobromide and processes for the production thereof