Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB11068/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex SA
Original Assignee
Syntex SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex SAfiledCriticalSyntex SA
Publication of GB854409ApublicationCriticalpatent/GB854409A/en
C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
Abstract
The invention comprises compounds of the formula : <FORM:0854409/IV(b)/1> wherein R1 is hydrogen or acyl and R2 is lower alkyl of up to 6 carbons, and their preparation by treating the corresponding 2-unsubstituted compounds with ethyl formate in the presence of sodium hydride and if required esterifying the resulting 2-hydroxy-methylene compound. The reaction is preferably effected in benzene under nitrogen, and specified products include 2-hy-droxymethylene-17a -methyl and ethyl-androstan17b -ol-3-ones and their 2-acetate, propionate, cyclopentylpropionate and benzoate esters.
GB11068/60A1956-02-071957-01-25New cyclopentanophenanthrene derivatives and process for the production thereof
ExpiredGB854409A
(en)
A procedure for preparing new derivatives of 6-methyl and 1,6-dimethyl-8- (alpha-hydroxy-alkyl) -ergoline i (Machine-translation by Google Translate, not legally binding)
Procedure for the acetilation of organic combinations by means of acetic anhydride associated with diocylphosphoric acid as a catalyst (Machine-translation by Google Translate, not legally binding)