GB851660A - Novel tertiary amines and processes for their production - Google Patents

Novel tertiary amines and processes for their production

Info

Publication number
GB851660A
GB851660A GB916/59A GB91659A GB851660A GB 851660 A GB851660 A GB 851660A GB 916/59 A GB916/59 A GB 916/59A GB 91659 A GB91659 A GB 91659A GB 851660 A GB851660 A GB 851660A
Authority
GB
United Kingdom
Prior art keywords
formula
reacting
compound
processes
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB916/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB851660A publication Critical patent/GB851660A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises compounds of the general formula: <FORM:0851660/IV(b)/1> and acid addition salts thereof, where Hal represents a halogen atom, <FORM:0851660/IV(b)/2> represents a piperidino or pyrrolidino radical and Y represents a straight or branched chain alkyl group, and the preparation thereof by reacting a compound of the formula : <FORM:0851660/IV(b)/3> with a nitrile of the formula : <FORM:0851660/IV(b)/4> or by reacting a nitrile of the formula : <FORM:0851660/IV(b)/5> with Y-Mg-Hal or by reductively aminating a ketone of the formula : <FORM:0851660/IV(b)/6> with piperidine or pyrrolidine or by reacting a compound of the formula : <FORM:0851660/IV(b)/7> with a 1,4-dihalogenobutane or a 1,5-dihalogenopentane or by reacting a compound of the formula : <FORM:0851660/IV(b)/8> with piperidine or pyrrolidine in the presence of an alkali-metal catalyst and, if desired, converting the products of any of the above processes into their acid-addition salts. The products are hypertensives.
GB916/59A 1958-01-10 1959-01-09 Novel tertiary amines and processes for their production Expired GB851660A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE851660X 1958-01-10

Publications (1)

Publication Number Publication Date
GB851660A true GB851660A (en) 1960-10-19

Family

ID=6781873

Family Applications (1)

Application Number Title Priority Date Filing Date
GB916/59A Expired GB851660A (en) 1958-01-10 1959-01-09 Novel tertiary amines and processes for their production

Country Status (2)

Country Link
ES (1) ES245955A1 (en)
GB (1) GB851660A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198833A (en) * 1960-11-05 1965-08-03 Snc Science Union & Compagnie 1-(trifluoromethylphenyl)-2-loweralkyl aminopropanes and acid addition salts thereof
US3261749A (en) * 1962-10-12 1966-07-19 Boehringer Sohn Ingelheim Method of curbing appetite
US3261750A (en) * 1962-10-12 1966-07-19 Boehringer Sohn Ingelheim Method of curbing appetite

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198833A (en) * 1960-11-05 1965-08-03 Snc Science Union & Compagnie 1-(trifluoromethylphenyl)-2-loweralkyl aminopropanes and acid addition salts thereof
US3261749A (en) * 1962-10-12 1966-07-19 Boehringer Sohn Ingelheim Method of curbing appetite
US3261750A (en) * 1962-10-12 1966-07-19 Boehringer Sohn Ingelheim Method of curbing appetite

Also Published As

Publication number Publication date
ES245955A1 (en) 1960-01-01

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