GB850479A - Acylated amino-acids and amino-sugars - Google Patents
Acylated amino-acids and amino-sugarsInfo
- Publication number
- GB850479A GB850479A GB27128/57A GB2712857A GB850479A GB 850479 A GB850479 A GB 850479A GB 27128/57 A GB27128/57 A GB 27128/57A GB 2712857 A GB2712857 A GB 2712857A GB 850479 A GB850479 A GB 850479A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- acid
- reacted
- amino
- taurine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention comprises compounds of the formula Ph.CH(C2H5) CO.NHR wherein Ph is a phenyl or biphenylylradical and -NHR is the residue of an amino acid or an amino sugar, and their preparation by reacting a -phenyl- or a -biphenylylbutyric acid or a reactive derivative thereof, e.g. a halide or the anhydride; with an amino acid, an ester thereof or an amino sugar and, if necessary, hydrolysing the product obtained. The process may be conducted in an aqueous solvent containing an acid acceptor, such as the hydroxide or carbonate of an alkali metal or alkaline earth metal. If the free substituted butyric acid or a salt thereof is used in the process, a catalyst such as ethyl dichlorophosphite, triethylamine or a carbodimide may also be added. In examples a -phenyl-butryl chloride is reacted with taurine, d-glucosamine hydrochloride and l-glutanic acid, a -phenyl-butyric acid is reacted with, separately, methyl and ethyl dl-methioninates and the initial products hydrolysed with sodium hydronide, p-bipherylyl-butryl chloride is reacted with taurine, dl-methionine and d-gluosamine and a -phenyl-butryl anhydride is reacted with taurine to give products of the above general formula, some of which are isolated as their sodium salts. The use of chondrosamine is also referred to. The subject-matter of Specification 766,246 is disclaimed.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP850479X | 1956-09-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB850479A true GB850479A (en) | 1960-10-05 |
Family
ID=13847762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB27128/57A Expired GB850479A (en) | 1956-09-05 | 1957-08-28 | Acylated amino-acids and amino-sugars |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB850479A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2480747A1 (en) * | 1980-04-17 | 1981-10-23 | Roques Bernard | AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION |
-
1957
- 1957-08-28 GB GB27128/57A patent/GB850479A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2480747A1 (en) * | 1980-04-17 | 1981-10-23 | Roques Bernard | AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION |
EP0038758A1 (en) * | 1980-04-17 | 1981-10-28 | Societe Civile Bioprojet | Amino-acids derivatives and their therapeutic use |
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