GB850479A - Acylated amino-acids and amino-sugars - Google Patents

Acylated amino-acids and amino-sugars

Info

Publication number
GB850479A
GB850479A GB27128/57A GB2712857A GB850479A GB 850479 A GB850479 A GB 850479A GB 27128/57 A GB27128/57 A GB 27128/57A GB 2712857 A GB2712857 A GB 2712857A GB 850479 A GB850479 A GB 850479A
Authority
GB
United Kingdom
Prior art keywords
phenyl
acid
reacted
amino
taurine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB27128/57A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of GB850479A publication Critical patent/GB850479A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

The invention comprises compounds of the formula Ph.CH(C2H5) CO.NHR wherein Ph is a phenyl or biphenylylradical and -NHR is the residue of an amino acid or an amino sugar, and their preparation by reacting a -phenyl- or a -biphenylylbutyric acid or a reactive derivative thereof, e.g. a halide or the anhydride; with an amino acid, an ester thereof or an amino sugar and, if necessary, hydrolysing the product obtained. The process may be conducted in an aqueous solvent containing an acid acceptor, such as the hydroxide or carbonate of an alkali metal or alkaline earth metal. If the free substituted butyric acid or a salt thereof is used in the process, a catalyst such as ethyl dichlorophosphite, triethylamine or a carbodimide may also be added. In examples a -phenyl-butryl chloride is reacted with taurine, d-glucosamine hydrochloride and l-glutanic acid, a -phenyl-butyric acid is reacted with, separately, methyl and ethyl dl-methioninates and the initial products hydrolysed with sodium hydronide, p-bipherylyl-butryl chloride is reacted with taurine, dl-methionine and d-gluosamine and a -phenyl-butryl anhydride is reacted with taurine to give products of the above general formula, some of which are isolated as their sodium salts. The use of chondrosamine is also referred to. The subject-matter of Specification 766,246 is disclaimed.
GB27128/57A 1956-09-05 1957-08-28 Acylated amino-acids and amino-sugars Expired GB850479A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP850479X 1956-09-05

Publications (1)

Publication Number Publication Date
GB850479A true GB850479A (en) 1960-10-05

Family

ID=13847762

Family Applications (1)

Application Number Title Priority Date Filing Date
GB27128/57A Expired GB850479A (en) 1956-09-05 1957-08-28 Acylated amino-acids and amino-sugars

Country Status (1)

Country Link
GB (1) GB850479A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480747A1 (en) * 1980-04-17 1981-10-23 Roques Bernard AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480747A1 (en) * 1980-04-17 1981-10-23 Roques Bernard AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
EP0038758A1 (en) * 1980-04-17 1981-10-28 Societe Civile Bioprojet Amino-acids derivatives and their therapeutic use

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