GB849072A - Improvements in or relating to steroids and the manufacture thereof - Google Patents

Improvements in or relating to steroids and the manufacture thereof

Info

Publication number
GB849072A
GB849072A GB1089/59A GB108959A GB849072A GB 849072 A GB849072 A GB 849072A GB 1089/59 A GB1089/59 A GB 1089/59A GB 108959 A GB108959 A GB 108959A GB 849072 A GB849072 A GB 849072A
Authority
GB
United Kingdom
Prior art keywords
dimethylandrostane
hydroxyandrostan
diol
hydroxy
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1089/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB849072A publication Critical patent/GB849072A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises a compound having the formula: <FORM:0849072/IV(b)/1> wherein R is keto or b -hydroxy and a process for the production thereof which comprises treating 6, 17a -dimethyltestosterone with a reducing agent selected from the group consisting of alkali metals in liquid ammonia and hydrogen over a palladium catalyst. Illustrative products of the invention are 6a , 17a -dimethylandrostane-3b , 17b -diol, 6b , 17a -dimethylandrostane-3b , 17b -diol, 6a , 17a -dimethyl-17b -hydroxyandrostan-3-one, 6b , 17a -dimethyl-17b -hydroxyandrostan-3-one.ALSO:Compounds having the formula:- <FORM:0849072/VI/1> wherein R represents keto or b -hydroxy, can be administered in the forms of pills, tablets, capsules, syrups or elixirs for oral use, or in liquid forms which are adaptable to the natural and synthetic cortical steroid hormones for injectable products.
GB1089/59A 1958-02-10 1959-01-12 Improvements in or relating to steroids and the manufacture thereof Expired GB849072A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US849072XA 1958-02-10 1958-02-10

Publications (1)

Publication Number Publication Date
GB849072A true GB849072A (en) 1960-09-21

Family

ID=22187955

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1089/59A Expired GB849072A (en) 1958-02-10 1959-01-12 Improvements in or relating to steroids and the manufacture thereof

Country Status (1)

Country Link
GB (1) GB849072A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126399A (en) * 1964-03-24 Lower alkanoyl

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126399A (en) * 1964-03-24 Lower alkanoyl

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