GB835836A - The preparation of 1, 4-pregnadienes - Google Patents

The preparation of 1, 4-pregnadienes

Info

Publication number
GB835836A
GB835836A GB3263/58A GB326358A GB835836A GB 835836 A GB835836 A GB 835836A GB 3263/58 A GB3263/58 A GB 3263/58A GB 326358 A GB326358 A GB 326358A GB 835836 A GB835836 A GB 835836A
Authority
GB
United Kingdom
Prior art keywords
pregnadienes
prepared
preparation
hydrogen
pregnadiene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3263/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB835836A publication Critical patent/GB835836A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,4-Pregnadienes of the general formula <FORM:0835836/IV (b)/1> wherein R and R1 represent hydrogen or alkanoyl radicals containing up to 6 carbon atoms and X represents a halogen, are prepared by reacting the corresponding 4-pregnene with selenium dioxide and, when required, converting R and R1 to hydrogen e.g. by reaction with an alkali metal alkoxide. In the examples 9a - fluoro - 11b ,16a ,17a ,21 - tetrahydroxy - 1,4 - pregnadiene - 3,20 - dione and the corresponding 16a ,21-diacetoxy compound are prepared. Specifications 824,351 and 835,557 are referred to.
GB3263/58A 1957-02-21 1958-01-31 The preparation of 1, 4-pregnadienes Expired GB835836A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US835836XA 1957-02-21 1957-02-21

Publications (1)

Publication Number Publication Date
GB835836A true GB835836A (en) 1960-05-25

Family

ID=22179280

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3263/58A Expired GB835836A (en) 1957-02-21 1958-01-31 The preparation of 1, 4-pregnadienes

Country Status (1)

Country Link
GB (1) GB835836A (en)

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